Patents by Inventor Jeroen van Ameijde

Jeroen van Ameijde has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modified tyrosine amino acids, peptides containing them, and their use for detecting hydrolase enzyme activity
    Patent number: 9448237
    Abstract: The present invention relates to a method and tools which allow the kinetic monitoring of hydrolase enzyme activity. The present invention also aims to provide synthetic peptides and peptide residues modified such that they can be used in assays for monitoring hydrolase enzyme activity, and preferably phosphatase activity. Also claimed are modified tyrosine amino acid derivatives of formula (IV), wherein Y is chosen from —POy2? with y equal to 2 or 3 and esters thereof, —SOZ? with z equal to 2 or 3 and esters thereof, a carbohydrate or carbohydrate derivatives; and; wherein X1 and/or X2 is selected from —N3, —NO2, —CI, or —CN, —SCN, a C1 to C8 alkyl, or H, wherein either X1 or X2 is not H.
    Type: Grant
    Filed: May 18, 2012
    Date of Patent: September 20, 2016
    Assignees: PAMGENE B.V., UNIVERSITEIT UTRECHT HOLDING B.V.
    Inventors: Robby Ruijtenbeek, Jeroen van Ameijde, Robertus Matthias Joseph Liskamp
  • MODIFIED TYROSINE AMINO ACIDS, PEPTIDES CONTAINING THEM, AND THEIR USE FOR DETECTING HYDROLASE ENZYME ACTIVITY
    Publication number: 20140155286
    Abstract: The present invention relates to a method and tools which allow the kinetic monitoring of hydrolase enzyme activity. The present invention also aims to provide synthetic peptides and peptide residues modified such that they can be used in assays for monitoring hydrolase enzyme activity, and preferably phosphatase activity. Also claimed are modified tyrosine amino acid derivatives of formula (IV), wherein Y is chosen from —POy2? with y equal to 2 or 3 and esters thereof, —SOz? with z equal to 2 or 3 and esters thereof, a carbohydrate or carbohydrate derivatives; and; wherein X1 and/or X2 is selected from —N3, —NO2, —CI, or —CN, —SCN, a C1 to C8 alkyl, or H, wherein either X1 or X2 is not H.
    Type: Application
    Filed: May 18, 2012
    Publication date: June 5, 2014
    Applicant: PamGene B.V.
    Inventors: Robby Ruijtenbeek, Jeroen van Ameijde, Robertus Matthias Joseph Liskamp