Patents by Inventor Jerold Chun

Jerold Chun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12280063
    Abstract: Described herein are methods for inhibiting generation of one or more non-classical variant(s) of amyloid precursor protein (APP) gene. Provided herein are methods for diagnosing an individual having or suspected of having Alzheimer's-disease following identification of an expression profile or an activity profile of the one or more non-classical variant(s) and treating the individual using a reverse transcriptase inhibitor or salt thereof.
    Type: Grant
    Filed: June 20, 2019
    Date of Patent: April 22, 2025
    Assignee: SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE
    Inventors: Jerold Chun, William J. Romanow, Ming-Hsiang Lee, Victoria Blaho
  • Publication number: 20210267995
    Abstract: Described herein are methods for inhibiting generation of one or more non-classical variant(s) of amyloid precursor protein (APP) gene. Provided herein are methods for diagnosing an individual having or suspected of having Alzheimer's-disease following identification of an expression profile or an activity profile of the one or more non-classical variant(s) and treating the individual using a reverse transcriptase inhibitor or salt thereof.
    Type: Application
    Filed: June 20, 2019
    Publication date: September 2, 2021
    Inventors: Jerold CHUN, William J. ROMANOW, Ming-Hsiang LEE, Victoria BLAHO
  • Publication number: 20200080154
    Abstract: Described herein are methods for identifying and measuring one or more non-classical variant(s) of amyloid precursor protein (APP) gene. Provided herein are methods for diagnosing and treating an individual having or suspected of having Alzheimer's disease following identification of an expression profile or an activity profile of the one or more non-classical variant(s).
    Type: Application
    Filed: May 1, 2018
    Publication date: March 12, 2020
    Inventors: Jerold CHUN, Ming-Hsiang LEE
  • Publication number: 20080051372
    Abstract: The invention relates to methods of modulating neurite outgrowth, in culture or in a subject. The methods generally utilize cell-signaling phospholipids which interact and bind to the G protein-coupled cellular receptors (GPCRs). Such phospholipids include lysophospholipids, as well as synthetic lysophospholipid receptor agonists and antagonists that may be chemically distinct from lysophospholipids. The methods include contacting astrocytes with an effective amount of a lysophospholipid agent, and contacting neurons with the astrocytes. The methods also include treating neurons by contacting the neurons with astrocytes pretreated with a lysophospholipid agent. The methods further include contacting the neurons with an effective amount of an astrocyte-derived soluble factor (ADSF).
    Type: Application
    Filed: August 24, 2007
    Publication date: February 28, 2008
    Applicant: THE SCRIPPS RESEARCH INSTITUTE
    Inventor: Jerold Chun