Patents by Inventor Jerome Aubert

Jerome Aubert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of naratriptan in the treatment of rosacea
    Patent number: 9889126
    Abstract: Described herein is a method of using a topical, pharmaceutical composition, particularly a dermatological composition, comprising naratriptan to treat rosacea and in particular erythematotelangiectatic rosacea.
    Type: Grant
    Filed: December 18, 2014
    Date of Patent: February 13, 2018
    Assignee: GALDERMA RESEARCH & DEVELOPMENT
    Inventors: Michel Rivier, Isabelle Carlavan, Jerome Aubert
  • MODULATORS AND METHODS FOR THE TREATMENT OF ROSACEA
    Publication number: 20160000800
    Abstract: An in vitro method of screening candidate compounds for the preventive or curative treatment of rosacea is described. The method can include determining the capacity of a compound to modulate the expression or activity of the Transient Receptor Potential (TRPs), as well as the use of modulators of the expression or activity of this transcription factor for the treatment of rosacea. The method can also include in vitro diagnosis or prognosis of this pathology.
    Type: Application
    Filed: February 5, 2015
    Publication date: January 7, 2016
    Inventors: Jerome AUBERT, Martin Steinhoff
  • NOVEL BENZENESULFONAMIDE COMPOUNDS, METHOD FOR SYNTHESIZING SAME, AND USE THEREOF IN MEDICINE AS WELL AS IN COSMETICS
    Publication number: 20140275108
    Abstract: Provided herein are novel benzenesulfonamide compounds having a structure of formula (I) below: as well as to the method for synthesizing same and to the use thereof in pharmaceutical compositions to be used in human or veterinary medicine, as well as to the use thereof. Also provided herein are methods of using the disclosed pharmaceutical compositions for the treatment of neuroinflammatory skin diseases such as acne.
    Type: Application
    Filed: March 15, 2013
    Publication date: September 18, 2014
    Applicant: GALDERMA RESEARCH & DEVELOPMENT
    Inventors: Carine MOUNIER, Isabelle Carlavan, Jerome Aubert, André Jomard, Patricia Rossio
  • MODULATORS AND METHODS FOR THE TREATMENT OF ROSACEA
    Publication number: 20140031341
    Abstract: An in vitro method of screening candidate compounds for the preventive or curative treatment of rosacea is described. The method can include determining the capacity of a compound to modulate the expression or activity of the Transient Receptor Potential (TRPs), as well as the use of modulators of the expression or activity of this transcription factor for the treatment of rosacea. The method can also include in vitro diagnosis or prognosis of this pathology.
    Type: Application
    Filed: December 19, 2011
    Publication date: January 30, 2014
    Applicants: UNIVERSITAT MUNSTER, GALDERMA RESEARCH & DEVELOPMENT
    Inventors: Jerome Aubert, Martin Steinhoff
  • PACAP SIGNALING PATHWAY MODULATORS FOR TREATING INFLAMMATORY SKIN DISEASES HAVING A NEUROGENIC COMPONENT, NOTABLY ROSACEA, AND COMPOSITIONS COMPRISED THEREOF
    Publication number: 20110229423
    Abstract: Modulators of specific PACAP receptors are useful for treating inflammatory skin diseases having a neurogenic component, and more particularly rosacea and/or facial erythema, compositions containing these and screening methods are described for identifying PACAP signaling pathway modulators.
    Type: Application
    Filed: July 17, 2009
    Publication date: September 22, 2011
    Applicant: Galderma Research & Development
    Inventors: Johannes Voegel, Michel Rivier, Jerome Aubert, Martin Steinhoff
  • Methods of modulating PPAR gamma-type receptors
    Patent number: 8022079
    Abstract: Novel compounds having the general formula (I) below: are useful in a wide variety of applications in human or veterinary medicine (in dermatology, and also in the fields of cardiovascular diseases, immune diseases and/or diseases associated with lipid metabolism), or, alternatively are formulated into cosmetic compositions.
    Type: Grant
    Filed: September 18, 2009
    Date of Patent: September 20, 2011
    Assignee: Galderma Research & Development
    Inventors: Laurence Clary, Etienne Thoreau, Michel Rivier, Jerome Aubert, Laurent Chantalat, Johannes Voegel
  • Methods for activating PPAR gamma-type receptors
    Patent number: 7973063
    Abstract: Novel biaromatic compounds having the following structural formula (I): are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine, in particular in dermatology as well as in the fields of cardiovascular diseases, immune diseases and/or diseases related to the metabolism of lipids, or, alternatively, into cosmetic compositions.
    Type: Grant
    Filed: October 9, 2009
    Date of Patent: July 5, 2011
    Assignee: Galderma Research & Development
    Inventors: Jerome Aubert, Laurence Clary, Pascale Mauvais, Michel Rivier, Etienne Thoreau, Jean-Guy Boiteau
  • Compounds that modulate PPAR?-type receptors and cosmetic/pharmaceutical compositions comprising said compounds
    Patent number: 7968560
    Abstract: Novel compounds having the general formula (I) below: are useful in a wide variety of applications in human or veterinary medicine (in dermatology, and also in the fields of cardiovascular diseases, immune diseases and/or diseases associated with lipid metabolism), or, alternatively are formulated into cosmetic compositions.
    Type: Grant
    Filed: September 21, 2009
    Date of Patent: June 28, 2011
    Assignee: Galderma Research & Development
    Inventors: Laurence Clary, Etienne Thoreau, Michel Rivier, Jerome Aubert, Laurent Chantalat, Johannes Voegel
  • Compounds that modulate PPAR gamma-type receptors and cosmetic/pharmaceutical compositions comprising said compounds
    Publication number: 20100247468
    Abstract: Novel compounds having the general formula (I) below: are useful in a wide variety of applications in human or veterinary medicine (in dermatology, and also in the fields of cardiovascular diseases, immune diseases and/or diseases associated with lipid metabolism), or, alternatively are formulated into cosmetic compositions.
    Type: Application
    Filed: September 21, 2009
    Publication date: September 30, 2010
    Applicant: GALDERMA RESEARCH & DEVELOPMENT
    Inventors: Laurence Clary, Etienne Thoreau, Michel Rivier, Jerome Aubert, Laurent Chantalat, Johannes Voegel
  • METHODS OF MODULATING PPAR GAMMA-TYPE RECEPTORS
    Publication number: 20100099689
    Abstract: Novel compounds having the general formula (I) below: are useful in a wide variety of applications in human or veterinary medicine (in dermatology, and also in the fields of cardiovascular diseases, immune diseases and/or diseases associated with lipid metabolism), or, alternatively are formulated into cosmetic compositions.
    Type: Application
    Filed: September 18, 2009
    Publication date: April 22, 2010
    Applicant: GALDERMA RESEARCH & DEVELOPMENT
    Inventors: Laurence CLARY, Etienne Thoreau, Michel Rivier, Jerome Aubert, Laurent Chantalat, Johannes Voegel
  • Methods for activating PPAR gamma-type receptors
    Publication number: 20100035988
    Abstract: Novel biaromatic compounds having the following structural formula (I): are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine, in particular in dermatology as well as in the fields of cardiovascular diseases, immune diseases and/or diseases related to the metabolism of lipids, or, alternatively, into cosmetic compositions.
    Type: Application
    Filed: October 9, 2009
    Publication date: February 11, 2010
    Applicant: GALDERMA RESEARCH & DEVELOPMENT
    Inventors: Jerome Aubert, Laurence Clary, Pascale Mauvais, Michel Rivier, Etienne Thoreau, Jean-Guy Boiteau
  • Modulators of HSD17b7 for treating acne or hyperseborrhea
    Publication number: 20100028879
    Abstract: An in vitro method for screening candidate compounds for the preventive or curative treatment of acne, includes the determination of the capacity of a compound to modulate the expression or the activity of hydroxysteroid (17-beta) dehydrogenase type 7, and the use of modulators of the expression or activity of this enzyme for the treatment of acne or skin disorders associated with a hyperseborrhea; methods for the in vitro diagnosis or in vitro prognosis of these pathologies are also described.
    Type: Application
    Filed: January 21, 2009
    Publication date: February 4, 2010
    Applicant: GALDERMA RESEARCH & DEVELOPMENT
    Inventors: Fernand Labrie, Michel Rivier, Van Luu-The, Ezequiel L. Calvo, Jerome Aubert, Sophie Deret, Johannes Voegel
  • Modulators of SC4MOL for treating acne or hyperseborrhea
    Publication number: 20100021892
    Abstract: An in vitro method for screening candidate compounds for the preventive or curative treatment of acne, includes the determination of the capacity of a compound to modulate the expression or the activity of sterol-C4-methyl oxidase (SC4MOL), and the use of modulators of the expression or activity of this enzyme for the treatment of acne or skin disorders associated with a hyperseborrhea; methods for the in vitro diagnosis or prognosis of these pathologies are also described.
    Type: Application
    Filed: January 21, 2009
    Publication date: January 28, 2010
    Applicant: GALDERMA RESEARCH & DEVELOPMENT
    Inventors: Fernand Labrie, Mohamed El-Alfy, Van Luu-The, Ezequiel L. Calvo, Jerome Aubert, Isabelle Carlavan, Sophie Deret, Johannes Voegel
  • Modulators of lanosterol synthetase for treating acne or hyperseborrhea
    Publication number: 20100021893
    Abstract: An in vitro method for screening candidate compounds for the preventive or curative treatment of acne, includes the determination of the capacity of a compound to modulate the expression or the activity of lanosterol synthetase (LSS), and the use of modulators of the expression or activity of this enzyme for the treatment of acne or skin disorders associated with a hyperseborrhea; methods for the in vitro diagnosis or prognosis of these pathologies are also described.
    Type: Application
    Filed: January 21, 2009
    Publication date: January 28, 2010
    Applicant: GALDERMA RESEARCH & DEVELOPMENT
    Inventors: Fernand Labrie, Mohamed El-Alfy, Van Luu-The, Ezequiel L. Calvo, Jerome Aubert, Pascal Collette, Johannes Voegel
  • Biaromatic compounds which activate PPAR?-type receptors and cosmetic/pharmaceutical compositions comprised thereof
    Patent number: 7626054
    Abstract: Novel biaromatic compounds having the following structural formula (I): are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine, in particular in dermatology as well as in the fields of cardiovascular diseases, immune diseases and/or diseases related to the metabolism of lipids, or, alternatively, into cosmetic compositions.
    Type: Grant
    Filed: November 3, 2006
    Date of Patent: December 1, 2009
    Assignee: Galderma Research & Development
    Inventors: Jerome Aubert, Laurence Clary, Pascale Mauvais, Michel Rivier, Etienne Thoreau, Jean-Guy Boiteau
  • Compounds that modulate PPAR? type receptors and cosmetic/pharmaceutical compositions comprised thereof
    Patent number: 7625914
    Abstract: Novel compounds having the general formula (I) below: are useful in a wide variety of applications in human or veterinary medicine (in dermatology, and also in the fields of cardiovascular diseases, immune diseases and/or diseases associated with lipid metabolism), or, alternatively are formulated into cosmetic compositions.
    Type: Grant
    Filed: December 20, 2005
    Date of Patent: December 1, 2009
    Assignee: Galderma Research & Development
    Inventors: Laurence Clary, Etienne Thoreau, Michel Rivier, Jerome Aubert, Laurent Chantalat, Johannes Voegel
  • Modulators of scarb-1 for treating acne or hyperseborrhea
    Publication number: 20090246776
    Abstract: An in vitro method for screening candidate compounds for the preventive or curative treatment of acne, includes the determination of the capacity of a compound to modulate the expression or the activity of the SCARB-1 receptor, and the use of modulators of the expression or activity of this receptor for the treatment of acne or skin disorders associated with a hyperseborrhea; methods for the in vitro diagnosis or prognosis of these pathologies are also described.
    Type: Application
    Filed: January 21, 2009
    Publication date: October 1, 2009
    Applicant: GALDERMA RESEARCH & DEVELOPMENT
    Inventors: Fernand Labrie, Isabelle Carlavan, Pascal Collette, Ezequiel L. Calvo, Jerome Aubert, Johannes Voegel
  • 5-HT4 partial agonist pharmaceutical compositions
    Publication number: 20090104263
    Abstract: A solid pharmaceutical composition for oral administration comprising tegaserod in base or salt form in an amount of up to 10% by weight a bulking agent in an amount of 70 to 90% by weight a disintegrant in an amount of less than 15% by weight a glidant and a lubricant,
    Type: Application
    Filed: October 7, 2008
    Publication date: April 23, 2009
    Inventors: Jerome Aubert, Christian Vitzling
  • Novel biaromatic compounds which activate PPARy-type receptors and cosmetic/pharmaceutical compositions comprised thereof
    Publication number: 20070112070
    Abstract: Novel biaromatic compounds having the following structural formula (I): are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine, in particular in dermatology as well as in the fields of cardiovascular diseases, immune diseases and/or diseases related to the metabolism of lipids, or, alternatively, into cosmetic compositions.
    Type: Application
    Filed: November 3, 2006
    Publication date: May 17, 2007
    Applicant: GALDERMA RESEARCH & DEVELOPMENT
    Inventors: Jerome Aubert, Laurence Clary, Pascale Mauvais, Michel Rivier, Etienne Thoreau, Jean-Guy Boiteau
  • Novel compounds that modulate PPARy type receptors and cosmetic/pharmaceutical compositions comprised thereof
    Publication number: 20060148862
    Abstract: Novel compounds having the general formula (I) below: are useful in a wide variety of applications in human or veterinary medicine (in dermatology, and also in the fields of cardiovascular diseases, immune diseases and/or diseases associated with lipid metabolism), or, alternatively are formulated into cosmetic compositions.
    Type: Application
    Filed: December 20, 2005
    Publication date: July 6, 2006
    Applicant: GALDERMA RESEARCH & DEVELOPMENT, S.N.C.
    Inventors: Laurence Clary, Etienne Thoreau, Michel Rivier, Jerome Aubert, Laurent Chantalat, Johannes Voegel