Patents by Inventor Jerome B. Posner

Jerome B. Posner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ma family polypeptides and anti-Ma antibodies
    Patent number: 7026450
    Abstract: Ma family polypeptides Ma1, Ma2, Ma3, Ma4 and Ma5 are disclosed, as are nucleic acids encoding the Ma family polypeptides, antibodies that bind to Ma family polypeptides, and methods of diagnosis of paraneoplastic syndromes, by assessing a test sample from an individual for the presence or absence, or amount, of antibodies to Ma family polypeptides.
    Type: Grant
    Filed: January 4, 2002
    Date of Patent: April 11, 2006
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Jerome B. Posner, Josep O. Dalmau, Myrna R. Rosenfeld
  • Ma family polypeptides and anti-Ma antibodies
    Publication number: 20020123114
    Abstract: Ma family polypeptides Ma1, Ma2, Ma3, Ma4 and Ma5 are disclosed, as are nucleic acids encoding the Ma family polypeptides, antibodies that bind to Ma family polypeptides, and methods of diagnosis of paraneoplastic syndromes, by assessing a test sample from an individual for the presence or absence, or amount, of antibodies to Ma family polypeptides.
    Type: Application
    Filed: January 4, 2002
    Publication date: September 5, 2002
    Applicant: Sloan-Kettering Institute for Cancer Research
    Inventors: Jerome B. Posner, Josep O. Dalmau, Myrna R. Rosenfeld
  • Ma family polypeptides and anti-Ma antibodies
    Patent number: 6387639
    Abstract: Ma family polypeptides Ma1, Ma2, Ma3, Ma4 and Ma5 are disclosed, as are nucleic acids encoding the Ma family polypeptides, antibodies that bind to Ma family polypeptides, and methods of diagnosis of paraneoplastic syndromes, by assessing a test sample from an individual for the presence or absence, or amount, of antibodies to Ma family polypeptides.
    Type: Grant
    Filed: November 10, 1998
    Date of Patent: May 14, 2002
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Jerome B. Posner, Josep O. Dalmau, Myrna R. Rosenfeld
  • Antigen recognized by patients with antibody associated paraneoplastic sensory neuronopathy, DNA encoding same and uses thereof
    Patent number: 6193948
    Abstract: An isolated nucleic acid sequence encoding Hu paraneoplastic antigenic polypeptide is provided by this invention. This invention also provides a purified Hu antigenic polypeptide and compositions containing the purified Hu antigenic polypeptide. Further provided by this invention is a monoclonal antibody directed to an epitope on the Hu paraneoplastic antigenic polypeptide. Compositions containing this monoclonal antibody also are provided by this invention. This invention also provides methods of diagnosis and treatment using the compositions described hereinabove.
    Type: Grant
    Filed: May 21, 1998
    Date of Patent: February 27, 2001
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Jerome B. Posner, Henry M. Furneaux
  • Antigen recognized by patients with antibody associated cerebellar degeneration, DNA encoding same and uses thereof
    Patent number: 5925526
    Abstract: An isolated nucleic acid sequence encoding major Yo paraneoplastic antigenic polypeptide is provided by this invention. This invention also provides a purified major Yo antigenic polypeptide and compositions containing the purified major Yo antigenic polypeptide. Further provided by this invention is a monoclonal antibody directed to an epitope on the major Yo paraneoplastic antigenic polypeptide. Compositions containing this monoclonal antibody also are provided by this invention. This invention also provides methods of diagnosis and treatment using the compositions described hereinabove.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: July 20, 1999
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Jerome B. Posner, Henry M. Furneaux
  • Antigen recognized by patients with antibody associated paraneoplastic sensory neuronopathy, DNA encoding same and uses thereof
    Patent number: 5807705
    Abstract: An isolated nucleic acid sequence encoding Hu paraneoplastic antigenic polypeptide is provided by this invention. This invention also provides a purified Hu antigenic polypeptide and compositions containing the purified Hu antigenic polypeptide. Further provided by this invention is a monoclonal antibody directed to an epitope on the Hu paraneoplastic antigenic polypeptide. Compositions containing this monoclonal antibody also are provided by this invention. This invention also provides methods of diagnosis and treatment using the compositions described hereinabove.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: September 15, 1998
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Jerome B. Posner, Henry M. Furneaux
  • Antigen recognized by patients with antibody associated paraneoplastic cerebellar degeneration, DNA encoding same and uses thereof
    Patent number: 5668013
    Abstract: An isolated nucleic acid sequence encoding major Yo paraneoplastic antigenic polypeptide is provided by this invention. This invention also provides a purified major Yo antigenic polypeptide and compositions containing the purified major Yo antigenic polypeptide. Further provided by this invention is a monoclonal antibody directed to an epitope on the major Yo paraneoplastic antigenic polypeptide. Compositions containing this monoclonal antibody also are provided by this invention. This invention also provides methods of diagnosis and treatment using the compositions described hereinabove.
    Type: Grant
    Filed: April 24, 1995
    Date of Patent: September 16, 1997
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Jerome B. Posner, Henry M. Furneaux
  • Ri fusion antigen recognized by antibodies associated with paraneoplastic opsoclonus and methods of use thereof
    Patent number: 5614371
    Abstract: An isolated nucleic acid sequence encoding Ri paraneoplastic antigenic polypeptide is provided by this invention. This invention also provides a purified Ri antigenic polypeptide and compositions containing the purified Ri antigenic polypeptide. Further provided by this invention is a antibody directed to an epitope on the Ri paraneoplastic antigenic polypeptide. Compositions containing this antibody also are provided by this invention. This invention also provides methods of diagnosis and treatment using the compositions described hereinabove.
    Type: Grant
    Filed: January 26, 1994
    Date of Patent: March 25, 1997
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Jerome B. Posner, Robert B. Darnell, Henry M. Furneaux
  • Antigen recognized by patients with antibody associated paraneoplastic sensory neuronopathy
    Patent number: 5603934
    Abstract: An isolated nucleic acid sequence encoding Hu paraneoplastic antigenic polypeptide is provided by this invention. This invention also provides a purified Hu antigenic polypeptide and compositions containing the purified Hu antigenic polypeptide. Further provided by this invention is a monoclonal antibody directed to an epitope on the Hu paraneoplastic antigenic polypeptide. Compositions containing this monoclonal antibody also are provided by this invention. This invention also provides methods of diagnosis and treatment using the compositions described hereinabove.
    Type: Grant
    Filed: March 18, 1994
    Date of Patent: February 18, 1997
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Jerome B. Posner, Henry M. Furneaux