Patents by Inventor Jerome BUSSEROLLES

Jerome BUSSEROLLES has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL PEPTOIDS AND USE THEREOF FOR PREVENTING OR TREATING CHRONIC PAIN
    Publication number: 20230374067
    Abstract: The invention concerns new peptidomimetic (or peptoid) molecules for the prevention and/or treatment of chronic pain, particularly that resulting from peripheral neuropathies.
    Type: Application
    Filed: September 30, 2021
    Publication date: November 23, 2023
    Inventors: Jérôme BUSSEROLLES, Emmanuel BOURINET, Claude TAILLEFUMIER, Olivier ROY, Lionel NAUTON, Youssef AISSOUNI
  • Pain relief compounds
    Patent number: 10214476
    Abstract: The present invention relates to the use of compounds for the treatment or prevention of pain in mammals, in particularly in human beings, and also to a process for preparing these compounds.
    Type: Grant
    Filed: December 31, 2012
    Date of Patent: February 26, 2019
    Assignees: ECOLE NATIONALE SUPERIEURE DE CHIMIE DE CLERMONT FERRAND, UNIVERSITÉ CLERMONT AUVERGNE
    Inventors: Sylvie Ducki, Khalil Bennis, Alain Eschalier, Jérôme Busserolles, Florian Lesage, Nuno Rodrigues, Delphine Vivier
  • Use of riluzole for treating or preventing the adverse effects of antineoplastic agents
    Patent number: 9511045
    Abstract: This invention relates to riluzole for use in the treatment or prevention of adverse effects associated with the administration of anticancer agents having neurotoxic effects, such as, for example, platinum salts, taxanes and periwinkle alkaloids.
    Type: Grant
    Filed: March 2, 2011
    Date of Patent: December 6, 2016
    Assignee: UNIVERSITE D'AUVERGNE CLERMONT I
    Inventors: Jérôme Busserolles, Abdelkrim Alloui, Michel Lazdunski, Alain Eschalier
  • Use of K2P potassium channel activators as antalgics
    Patent number: 9448242
    Abstract: The present invention relates to treating and preventing pain. More particularly the present invention demonstrates the involvement of K2P potassium channels in the antalgic effect of morphine. The present invention therefore provides a screening method for identifying antalgics.
    Type: Grant
    Filed: September 21, 2010
    Date of Patent: September 20, 2016
    Assignee: UNIVERSITE D'AUVERGNE CLERMONT I
    Inventors: Alain Eschalier, Jéröme Busserolles, Abdelkrim Alloui, Michel Lazdunski
  • Hypophosphorous acid derivatives having antihyperalgic activity and biological applications thereof
    Patent number: 9212196
    Abstract: The invention relates to hypophosphorous acid derivatives of formula (I) wherein —X is H or OH, —R represents one or several radicals R1-R5, identical or different, two of R1-R5 optionally occupying the same position on the phenyl group, one to four of R1-R5 being H and the others being selected in the group comprising -0-(CH2)n—COOH; —S—(CH2)n—COOH; —NH—(CH2)n—COOH; -0-(CH,R?)—COOH; —O—(CH2)n—OH; OR?, —R? being a C1-C3 alkyl radical; —OH; —COOH; halogen, particularly —F, —CI, —Br, —I, —CF3; —OCF3; —N02; —CH?CH—COOH; —(CH2)n—COOH; O—(CH2)n—P03H2; O—(CF2)n—P03H2; O—(CH2)n—S03H; O—(CH2)n—CONHOH; O—(CH2)n-tetrazol; O—(CH2)n-hydroxyisoxazol—n=1 to 5, preferably 1-3; said hypophosrous acid derivatives being diastereoisomers or enantiomers.
    Type: Grant
    Filed: May 16, 2012
    Date of Patent: December 15, 2015
    Assignees: UNIVERSITE PARIS DESCARTES, UNIVERSITE D'AUVERGNE
    Inventors: Francine Acher, Jean-Philippe Pin, Cyril Goudet, Alain Eschalier, Jérôme Busserolles, Delphine Rigault, Isabelle Lemasson, Sara Cesarini, Bruno Commare
  • PAIN RELIEF COMPOUNDS
    Publication number: 20150274633
    Abstract: The present invention relates to the use of compounds for the treatment or prevention of pain in mammals, in particularly in human beings, and also to a process for preparing these compounds.
    Type: Application
    Filed: December 31, 2012
    Publication date: October 1, 2015
    Inventors: Sylvie DUCKI, Khalil BENNIS, Alain ESCHALIER, Jerome BUSSEROLLES, Florian LESAGE, Nuno RODRIGUES, Delphine VIVIER
  • PAIN RELIEF COMPOUNDS
    Publication number: 20150038466
    Abstract: The present invention relates to the use of compounds for the treatment or prevention of pain in mammals, in particularly in human beings, and also to a process for preparing these compounds.
    Type: Application
    Filed: December 31, 2012
    Publication date: February 5, 2015
    Inventors: Sylvie Ducki, Khalil Bennis, Alain Eschalier, Jérôme Busserolles, Florian Lesage, Nuno Rodriguez, Delphine Vivier
  • HYPOPHOSPHOROUS ACID DERIVATIVES HAVING ANTIHYPERALGIC ACTIVITY AND BIOLOGICAL APPLICATIONS THEREOF
    Publication number: 20140107078
    Abstract: The invention relates to hypophosphorous acid derivatives of formula (I) wherein —X is H or OH, —R represents one or several radicals R1-R5, identical or different, two of R1-R5 optionally occupying the same position on the phenyl group, one to four of R1-R5 being H and the others being selected in the group comprising -0-(CH2)n—COOH; —S—(CH2)n—COOH; —NH—(CH2)n—COOH; -0-(CH,R?)—COOH; —O—(CH2)n—OH; OR?, —R? being a C1-C3 alkyl radical; —OH; —COOH; halogen, particularly —F, —CI, —Br, —I, —CF3; —OCF3; —N02; —CH?CH—COOH; —(CH2)n—COOH; O—(CH2)n—P03H2; O—(CF2)n—P03H2; O—(CH2)n—S03H; O—(CH2)n—CONHOH; O—(CH2)n-tetrazol; O—(CH2)n-hydroxyisoxazol—n=1 to 5, preferably 1-3; said hypophosrous acid derivatives being diastereoisomers or enantiomers.
    Type: Application
    Filed: May 16, 2012
    Publication date: April 17, 2014
    Applicants: UNIVWESITE D"AUVERGNE, UNIVERSITE PARIS DESCARTES
    Inventors: Francine Acher, Jean-Philippe Pin, Cyril Goudet, Alain Eschalier, Jérôme Busserolles, Delphine Rigault, Isabelle Lemasson, Sara Cesarini, Brono Commare
  • USE OF RILUZOLE FOR TREATING OR PREVENTING THE ADVERSE EFFECTS OF ANTINEOPLASTIC AGENTS
    Publication number: 20130064775
    Abstract: This invention relates to riluzole for use in the treatment or prevention of adverse effects associated with the administration of anticancer agents having neurotoxic effects, such as, for example, platinum salts, taxanes and periwinkle alkaloids.
    Type: Application
    Filed: March 2, 2011
    Publication date: March 14, 2013
    Applicant: UNIVERSITE D'AUVERGNE CLERMONT I
    Inventors: Jérôme Busserolles, Abdelkrim Alloui, Michel Lazdunski, Alain Eschalier
  • Use of K2P Potassium Channel Activators as Antalgics
    Publication number: 20120260354
    Abstract: The present invention relates to treating and preventing pain. More particularly the present invention demonstrates the involvement of K2P potassium channels in the antalgic effect of morphine. The present invention therefore provides a screening method for identifying antalgics.
    Type: Application
    Filed: September 21, 2010
    Publication date: October 11, 2012
    Inventors: Alain Eschalier, Jéröme Busserolles, Abdelkrim Alloui, Michel Lazdunski
  • Use of prebiotics for preventing or treating oxidation stress
    Publication number: 20060252725
    Abstract: The invention relates to the use of prebiotics for the preparation of food preparations, functional foods, or pharmaceutical compositions for preventing or treating oxidative stress in particular linked to the consumption of fructose. The invention also relates to a food preparation comprising simple carbohydrates, in particular fructose, in combination with prebiotics.
    Type: Application
    Filed: December 17, 2003
    Publication date: November 9, 2006
    Inventors: Yves Rayssiguier, Jéromes Busserolles, André Mazur, Elyett Guex