Patents by Inventor Jerome C. Swartz

Jerome C. Swartz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for capture and selective release of nucleic acids using weakly basic polymer and amplification of same
    Patent number: 5582988
    Abstract: Nucleic acids can be made available for amplification or other treatment after lysis by contacting the lysate with specific weakly basic polymers to form a precipitate with the nucleic acids at acidic pH. After removing non-precipitated materials, the pH is then made basic, thereby releasing the nucleic acids from the polymer. This method for preparing specimen samples is simple and quite rapid, and the released nucleic acids can be further treated in hybridization assays or amplification procedures. The weakly basic polymers are water-soluble and cationic at acidic pH, but neutral in charge at basic pH.
    Type: Grant
    Filed: September 15, 1994
    Date of Patent: December 10, 1996
    Assignee: Johnson & Johnson Clinical Diagnostics, Inc.
    Inventors: John W. Backus, Tobias E. Ekeze, Jerome C. Swartz, Richard C. Sutton, Ignazio S. Ponticello, JoAnne H. Kerschner, John B. Findlay
  • Weakly basic polymerizable monomers and polymers prepared therefrom
    Patent number: 5523368
    Abstract: Weakly basic ethylenically unsaturated polymerizable monomers and polymers have been prepared. The monomers are represented by the structure (I): ##STR1## wherein R is hydrogen or methyl, and R.sup.1 is alkylene of 1 to 3 carbon atoms. The resulting polymers are water-soluble and cationic at acidic pH, but water-insoluble and neutral in charge at basic pH. The polymers are useful for precipitating nucleic acids.
    Type: Grant
    Filed: May 5, 1995
    Date of Patent: June 4, 1996
    Assignee: Johnson & Johnson Clinical Diagnostics, Inc.
    Inventors: Ignazio S. Ponticello, Jerome C. Swartz, Tobias E. Ekeze
  • Weakly basic polymerizable monomers and polymers prepared therefrom
    Patent number: 5434270
    Abstract: Weakly basic ethylenically unsaturated polymerizable monomers and polymers have been prepared. The monomers are represented by the structure (I): ##STR1## wherein R is hydrogen or methyl, and R.sup.1 is alkylene of 1 to 3 carbon atoms. The resulting polymers are water-soluble and cationic at acidic pH, but water-insoluble and neutral in charge at basic pH. The polymers are useful for precipitating nucleic acids.
    Type: Grant
    Filed: September 15, 1994
    Date of Patent: July 18, 1995
    Assignee: Eastman Kodak Company
    Inventors: Ignazio S. Ponticello, Jerome C. Swartz, Tobias E. Ekeze