Patents by Inventor Jerome F. McAleer
Jerome F. McAleer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7807031Abstract: An improved disposable glucose test strip for use in a test meter of the type which receives a disposable test strip and a sample of blood from a patient and performs an electrochemical analysis is made using a non-conductive integrated reagent/blood separation layer containing a filler, an enzyme effective to oxidize glucose, e.g., glucose oxidase, and a mediator effective to transfer electrons from the enzyme. The integrated layer formulation is printed over a conductive carbon element to form a working electrode. The filler, for example a silica filler, is selected to have a balance of hydrophobicity and hydrophilicity such that one drying it forms a two-dimensional network on the surface of the conductive element. The response of this test strip is essentially temperature independent over relevant temperature ranges and is substantially insensitive to the hematocrit of the patient.Type: GrantFiled: June 13, 2006Date of Patent: October 5, 2010Assignee: Diabetes Diagnostics, Inc.Inventors: Jerome F. McAleer, Manuel Alvarez-Icaza, Geoff Hall, Elliot V. Plotkin, David Scott, Oliver W. H. Davies
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Patent number: 7378007Abstract: An apparatus for detection and quantitation of an electrochemically-detectable analyte, such as glucose, in blood or interstitial fluid includes a meter unit, a lancet and an electrochemical sensor. Of these components, the meter is preferably reusable, while the lancet and the electrochemical sensor are preferably incorporated in assemblies intended for single-use. The meter unit has a housing, within which a lancet is engaged with a mechanism for moving then lancet; a connector disposed within the housing for engaging an electrochemical sensor specific for the analyte and transmitting a signal indicative of the amount of analyte, and a display operatively-associated with a connector for displaying the amount of the analyte to user. The electrochemical sensor is adapted for detection of a particular analyte. In addition, the electrochemical sensor has an absorptive member for uptake of a sample of blood or interstitial fluid.Type: GrantFiled: August 11, 2003Date of Patent: May 27, 2008Assignee: Diabetes Diagnostics, Inc.Inventors: Piet H. C. Moerman, Jerome F. McAleer, Matthias Stiene
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Patent number: 7112265Abstract: An improved disposable glucose test strip for use in a test meter of the type which receives a disposable test strip and a sample of blood from a patient and performs an electrochemical analysis using a non-conductive integrated reagent/blood separation layer (17) containing a filler, an enzyme effective to oxidize glucose, e.g., glucose oxidase, and a mediator effective to transfer electrons from the enzyme. The integrated layer formulation is printed over a conductive carbon element (16) to form a working electrode. The filler, for example a silica filler, is selected to have a balance of hydrophobicity such that on drying it forms a two-dimensional network on the surface of the conductive element. The response of this test strip is essentially temperature independent over relevant temperature ranges and is substantially insensitive to the hematocrit of the patient.Type: GrantFiled: January 11, 2000Date of Patent: September 26, 2006Assignee: Lifescan Scotland LimitedInventors: Jerome F. McAleer, Manuel Alvarez-Icaza, Geoff Hall, Elliot V. Plotkin, David Scott, Oliver W. H. Davies
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Patent number: 6706159Abstract: An apparatus for detection and quantitation of an electrochemically-detectable analyte, such as glucose, in blood or interstitial fluid includes a meter unit, a lancet and an electrochemical sensor. Of these components, the meter is preferably reusable, while the lancet and the electrochemical sensor are preferably incorporated in assemblies intended for single-use. The meter unit has a housing, within which a lancet is engaged with a mechanism for moving then lancet; a connector disposed within the housing for engaging an electrochemical sensor specific for the analyte and transmitting a signal indicative of the amount of analyte, and a display operatively-associated with a connector for displaying the amount of the analyte to user. The electrochemical sensor is adapted for detection of a particular analyte. In addition, the electrochemical sensor has an absorptive member for uptake of a sample of blood or interstitial fluid.Type: GrantFiled: March 2, 2000Date of Patent: March 16, 2004Assignee: Diabetes DiagnosticsInventors: Piet H. C. Moerman, Jerome F. McAleer, Matthias Stiene
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Publication number: 20020130042Abstract: An apparatus for detection and quantitation of an electrochemically-detectable analyte, such as glucose, in blood or interstitial fluid includes a meter unit, a lancet and an electrochemical sensor. Of these components, the meter is preferably reusable, while the lancet and the electrochemical sensor are preferably incorporated in assemblies intended for single-use. The meter unit has a housing, within which a lancet is engaged with a mechanism for moving then lancet; a connector disposed within the housing for engaging an electrochemical sensor specific for the analyte and transmitting a signal indicative of the amount of analyte, and a display operatively-associated with a connector for displaying the amount of the analyte to user. The electrochemical sensor is adapted for detection of a particular analyte. In addition, the electrochemical sensor has an absorptive member for uptake of a sample of blood or interstitial fluid.Type: ApplicationFiled: March 2, 2000Publication date: September 19, 2002Inventors: Piet H.C. Moerman, Jerome F. McAleer, Matthias Stiene
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Patent number: 6241862Abstract: An improved disposable glucose test strip for use in a test meter of the type which receives a disposable test strip and a sample of blood from a patient and performs an electrochemical analysis is made using a non-conductive integrated reagent/blood separation layer containing a filler, an enzyme effective to oxidize glucose, e.g., glucose oxidase, and a mediator effective to transfer electrons from the enzyme. The integrated layer formulation is printed over a conductive carbon element to form a working electrode. The filler, for example a silica filler, is selected to have a balance of hydrophobicity and hydrophilicity such that one drying it forms a two-dimensional network on the surface of the conductive element. The response of this test strip is essentially temperature independent over relevant temperature ranges and is substantially insensitive to the hematocrit of the patient.Type: GrantFiled: January 12, 1999Date of Patent: June 5, 2001Assignee: Inverness Medical Technology, Inc.Inventors: Jerome F. McAleer, Manuel Alvarez-Icaza, Geoff Hall, Elliot V. Plotkin, David Scott, Oliver W. H. Davies
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Patent number: 5989917Abstract: A test meter of the type which receives a disposable test strip and a sample of bodily fluid from a patient and performs an electrochemical analysis of the amount of an analyte such as glucose in the sample includes a receptacle for receiving a container in which disposable test strips are provided, and a mechanism for reading information about the disposable test strips that is affixed to the container. For example, calibration values can be applied to the container in the form of a machine readable bar-code, a magnetic stripe, a memory chip or as a resonant wire loop. By automatically obtaining calibration values from the container in which the strips are provided, the chances of using the wrong calibration information are greatly reduced. The container may also contain information readable by the meter including the expiration date, and the number of test strips in the container.Type: GrantFiled: February 13, 1996Date of Patent: November 23, 1999Assignee: Selfcare, Inc.Inventors: Jerome F. McAleer, Piet H. C. Moerman, Ta Siu
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Patent number: 5951836Abstract: An improved disposable glucose test strip for use in a test meter of the type which receives a disposable test strip and a sample of blood from a patient and performs an electrochemical analysis is made using a working formulation containing a filler, an enzyme effective to oxidize glucose, e.g., glucose oxidase, and a mediator effective to transfer electrons from the enzyme. The working formulation is printed over a conductive carbon base layer to form a working electrode. The filler, for example a silica filler, is selected to have a balance of hydrophobicity and hydrophilicity such that one drying it forms a two-dimensional network on the surface of the conductive base layer. The response of this test strip is essentially temperature independent over relevant temperature ranges and is substantially insensitive to the hematocrit of the patient.Type: GrantFiled: January 12, 1998Date of Patent: September 14, 1999Assignee: Selfcare, Inc.Inventors: Jerome F. McAleer, David Scott, Geoff Hall, Manuel Alvarez-Icaza, Elliot V. Plotkin
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Patent number: 5708247Abstract: An improved disposable glucose test strip for use in a test meter of the type which receives a disposable test strip and a sample of blood from a patient and performs an electrochemical analysis is made using a working formulation containing a filler, an enzyme effective to oxidize glucose, e.g., glucose oxidase, and a mediator effective to transfer electrons from the enzyme. The working formulation is printed over a conductive carbon base layer to form a working electrode. The filler, for example a silica filler, is selected to have a balance of hydrophobicity and hydrophilicity such that one drying it forms a two-dimensional network on the surface of the conductive base layer. The response of this test strip is essentially temperature independent over relevant temperature ranges and is substantially insensitive to the hematocrit of the patient.Type: GrantFiled: February 14, 1996Date of Patent: January 13, 1998Assignee: Selfcare, Inc.Inventors: Jerome F. McAleer, David Scott, Geoff Hall, Manuel Alvarez-Icaza, Elliot V. Plotkin
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Patent number: 5575930Abstract: A method of manufacturing a gas-permeable membrane for an amperometric gas electrode comprising demetallizing areas of a metallized film to obtain a regular array of gas-permeable micropores.Type: GrantFiled: March 27, 1995Date of Patent: November 19, 1996Inventors: Jordis Tietje-Girault, Brian J. Seddon, Jerome F. McAleer
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Patent number: 5264106Abstract: An amperometric sensor comprises a working electrode, a reference electrode, an enzyme whose catalytic activity on a substrate results in electroactivity, and an enhancer compound which enhances the detected electroactivity.Type: GrantFiled: March 18, 1993Date of Patent: November 23, 1993Assignee: Medisense, Inc.Inventors: Jerome F. McAleer, John T. Law, Richard A. Morris, Lesley Scott, John M. Mellor, Manus Dennison