Abstract: Provided herein are, inter alia, novel antibodies that bind to fms-like tyrosine kinase 3 (FLT3) thereby effectively targeting cells expressing FLT3. The antibodies provided herein may be used, inter alia, for therapeutic cancer applications, including, in some embodiments, treatment of multiple cancer types, which may include acute myeloid leukemia (AML), lymphoblastic leukemia (ALL), lung cancer, breast cancer, pancreatic cancer, ovarian cancer, colorectal cancer, renal cancer, or glioblastoma.

Abstract: Provided herein are, inter alia, novel antibodies that bind to cadherin-17 (CDH17) thereby effectively targeting cells expressing CHD17. The antibodies provided herein may be used, inter alia, for therapeutic cancer applications, including, in some embodiments, treatment of multiple cancer types, which may include gastrointestinal cancer, colorectal cancer, stomach cancer, pancreas cancer, neuroendocrine cancer, or ovarian cancer.

Abstract: Provided herein are, inter alia, novel antibodies that bind to V-domain Ig suppressor of T-cell activation (VISTA) thereby effectively targeting cells expressing VISTA. The antibodies provided herein may be used, inter alia, for therapeutic cancer applications, including, in some embodiments, treatment of multiple cancer types, which may include lung cancer, breast cancer, pancreatic cancer, ovarian cancer, colorectal cancer, renal cancer, or glioblastoma.

Abstract: Antibody-mediated rejection (ABMR) is one of the main obstacles to successful transplantation, including ABO blood group-incompatible (ABOi) transplantation. C4d deposition is a marker of ABMR and is also found in most ABOi allograft tissues. Described herein are anti-C4d CAR Tregs that suppress ABMR in ABOi allografts. Anti-C4d CAR Tregs prepared by retroviral transduction of CAR into CD62L +CD4 +CD25 +Tregs, expressed Foxp3, CD25, CTLA-4, LAP, and GITR to similar extents as non-transduced Tregs. Anti-C4d CAR Tregs were activated by specific binding to C4d and suppressed in vitro T cell proliferation as well as non-transduced Tregs. Furthermore, adoptive transfer of anti-C4d CAR Tregs significantly prolonged mouse ABOi heart allograft survival (P<0.05).

Abstract: Provided are a data communication method using a secure element and an electronic system adopting the same. The data communication method includes: exchanging certificate information between an application processor of an electronic device and a secure element; setting up a secure channel through mutual authentication between the application processor and the secure element by using a public key and a secret key after the exchange of the certification information; and performing data communication between the application processor and the secure element through the secure channel.

Abstract: In a method of controlling an electronic device using a wearable device, the electronic device is paired with the wearable device. A cryptographic key, which corresponds to the electronic device, is stored in a secure storage device included in the wearable device. A distance between the wearable device and the electronic device is estimated by the wearable device. An unlock signal including the cryptographic key, which is stored in the secure storage device, is transmitted from the wearable device to the electronic device when the estimated distance is smaller than a threshold distance. The electronic device is unlocked based on the unlock signal.

Abstract: A method for communicating medical data includes forming a secure channel between a first medical device and a second medical device connected to each other through a network on the basis of first authentication information of the first medical device and second authentication information of the second medical device; encrypting medical data that is obtained by the first medical device using a secure circuit that is provided in the first medical device; and transmitting the encrypted medical data to the second medical device through the secure channel.

Abstract: A method of data transfer in an electronic device including a secure module, which includes a processor and a secure element, an application processor, and a sensor, may include: switching an operation mode of the processor to a bypass mode; performing a cross-authentication, by the application processor and the secure element; generating a session key, by the application processor and the secure element, when the cross-authentication is succeeded; switching the operation mode of the processor to a normal mode; encrypting, by the secure module, sensing data provided by the sensor using the session key; transferring the encrypted sensing data from the processor to the application processor; and/or acquiring, by the application processor, the sensing data by decrypting the encrypted sensing data using the session key.

Abstract: A method for updating software includes verifying an update for first software that drives a security execution environment in a non-security execution environment, updating the first software by use of a first image of the first software update stored in the non-security execution environment, verifying an update for second software that drives a security device controlled by the security execution environment, in the security execution environment, and updating the second software by use of a second image of the second software update stored in the security execution environment.

Abstract: Provided are a data communication method using a secure element and an electronic system adopting the same. The data communication method includes: exchanging certificate information between an application processor of an electronic device and a secure element; setting up a secure channel through mutual authentication between the application processor and the secure element by using a public key and a secret key after the exchange of the certification information; and performing data communication between the application processor and the secure element through the secure channel.

Abstract: A method of data transfer in an electronic device including a secure module, which includes a processor and a secure element, an application processor, and a sensor, may include: switching an operation mode of the processor to a bypass mode; performing a cross-authentication, by the application processor and the secure element; generating a session key, by the application processor and the secure element, when the cross-authentication is succeeded; switching the operation mode of the processor to a normal mode; encrypting, by the secure module, sensing data provided by the sensor using the session key; transferring the encrypted sensing data from the processor to the application processor; and/or acquiring, by the application processor, the sensing data by decrypting the encrypted sensing data using the session key.

Abstract: A method for communicating medical data includes forming a secure channel between a first medical device and a second medical device connected to each other through a network on the basis of first authentication information of the first medical device and second authentication information of the second medical device; encrypting medical data that is obtained by the first medical device using a secure circuit that is provided in the first medical device; and transmitting the encrypted medical data to the second medical device through the secure channel.

Abstract: In a method of controlling an electronic device using a wearable device, the electronic device is paired with the wearable device. A cryptographic key, which corresponds to the electronic device, is stored in a secure storage device included in the wearable device. A distance between the wearable device and the electronic device is estimated by the wearable device. An unlock signal including the cryptographic key, which is stored in the secure storage device, is transmitted from the wearable device to the electronic device when the estimated distance is smaller than a threshold distance. The electronic device is unlocked based on the unlock signal.

Abstract: A method is for displaying a schedule in a wearable device is provided. The method includes displaying a watch screen on a display of the wearable device and displaying an event display icon corresponding to a scheduled event on the watch screen.