Patents by Inventor Jerome MAURY

Jerome MAURY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SEQUENCE FOR PROTEIN DECAY
    Publication number: 20250297290
    Abstract: The present invention relates to an expression cassette encoding a fusion protein comprising a nucleotide sequence encoding an amino acid sequence shown in SEQ ID NO: 1 or a fragment thereof, which directs protein decay, or encoding an amino acid sequence which is at least 60% identical to the amino acid sequence which directs protein decay; and also comprising a nucleotide sequence encoding a protein of interest, wherein the nucleotide sequences are fused together in frame. Further, the present invention relates to a vector comprising the expression cassette, a host cell comprising the expression cassette or a host cell comprising the vector which comprises the expression cassette. Additionally, the present invention relates to a method for the production of a triterpenoid using the host cell comprising the expression cassette of the present invention.
    Type: Application
    Filed: November 11, 2022
    Publication date: September 25, 2025
    Inventors: Lars M. BLANK, Birgitta E. EBERT, Hao GUO, Jochen FÖRSTER, Kerstin WALTER, Jerome MAURY, Christoph KNUF, Simo JACOBSEN
  • Microbial production of 3-hydroxypropionic acid
    Patent number: 10066245
    Abstract: A yeast cell having a reduced level of activity of NAD dependent glyceraldehyde-3-phosphate dehydrogenase (GAPDH) has at least one exogenous gene encoding NADP dependent GAPDH and/or has up-regulation of at least one endogenous gene expressing NADP dependent GAPDH, wherein combined expression of the enzymes NADP dependent GAPDH, PDC, ALD, ACS, ACC* and MCR in said host cell increases metabolic flux towards 3-HP via malonyl-CoA compared to an otherwise similar yeast cell lacking said genetic modification.
    Type: Grant
    Filed: June 12, 2014
    Date of Patent: September 4, 2018
    Assignee: TECHNICAL UNIVERSITY OF DENMARK
    Inventors: Niels Bjerg Jensen, Irina Borodina, Yun Chen, Jerome Maury, Kanchana Rueksomtawin Kildegaard, Jochen Förster, Jens Nielsen
  • MICROBIAL PRODUCTION OF 3-HYDROXYPROPIONIC ACID
    Publication number: 20160138056
    Abstract: A yeast cell having a reduced level of activity of NAD dependent glyceraldehyde-3-phosphate dehydrogenase (GAPDH) has at least one exogenous gene encoding NADP dependent GAPDH and/or has up-regulation of at least one endogenous gene expressing NADP dependent GAPDH, wherein combined expression of the enzymes NADP dependent GAPDH, PDC, ALD, ACS, ACC* and MCR in said host cell increases metabolic flux towards 3-HP via malonyl-CoA compared to an otherwise similar yeast cell lacking said genetic modification.
    Type: Application
    Filed: June 12, 2014
    Publication date: May 19, 2016
    Applicant: TECHNICAL UNIVERSITY OF DENMARK
    Inventors: Niels Bjerg JENSEN, Irina BORODINA, Yun CHEN, Jerome MAURY, Kanchana Rueksomtawin KILDEGAARD, Jochen FÖRSTER, Jens NIELSEN