Patents by Inventor Jerome Monbrun

Jerome Monbrun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200283387
    Abstract: The invention relates to a method for preparing a compound (I) or one of the salts thereof, and the uses of said method, R1OOC—C(?X)—CHR2R3(I), wherein X is selected among O; N—R?, wherein R? is H or a C1-C6 alkyl; and N—OR? wherein R? is H, or a C1-C6 alkyl or an alkylaryl; R1 is H or a C1-C6 alkyl group; R2 is H, a C1-C6 alkyl, or an alkylaryl; and R3 is CH2SR4 or CH2SeR4, where R4 is H or a C1-C6 alkyl from a compound (II), or one of the salts thereof, R1OOC—C(?X)—CHR2R5 and R5 is H or COOR6, where R6 is H or a C1-C6 alkyl, said method being carried out in the presence of a compound (III) CH2(Y)(Z).
    Type: Application
    Filed: January 17, 2017
    Publication date: September 10, 2020
    Inventors: Robert HUET, Vivien HENRYON, Jérôme MONBRUN, Etienne AIRIAU, Sylvain AUBRY, Patrick REY
  • Patent number: 9975911
    Abstract: The invention relates to compounds of formulae (Ia), (Ib) or (Ic) wherein, A1 and A2, identical or different, are H, (C1-C6) alkyl, (C1-C6) fluoroalkyl, (C2-C6) alkenyl, (C2-C6) alkynyl, (C1-C6) alkyl-ORa, (C1-C6) alkyl-SRa, (C1-C6) alkyl-NRaRb, ORa, SRa, NRaRb, or CORa; A3 is H, OH or form a carbonyl with A4; A4 is H, OH or form a carbonyl with A3; A5 is H, CRaRbOH, F, OH or forms a double bond with X in the case where X is CH; A6 is H or F; X is CH2, CHF, CF2, CHOH, O, S, NRa or a simple bond, or X is CH in the case where A5 forms with X a double bond; Y is P(O)(ORa)(ORb) or P(O)(ORa)(NRaRb); V is O or S; A7 is H, (C1-C6) alkyl, (C1-C6) fluoroalkyl, (C2-C6) alkenyl, (C2-C6) alkynyl or (C1-C6) alkyl-ORa; A8 is OH or H, Ra and Rb, identical or different, are H, (C1-C6) alkyl, (C1-C6) fluoroalkyl, (C1-C6) alkyl-OH or (C1-C6) alkyl-O—(C1-C6) alkyl; and their addition salts thereof with acids and bases, their preparation and their use in the antibacterial prevention and therapy, used alone or in association with
    Type: Grant
    Filed: October 28, 2013
    Date of Patent: May 22, 2018
    Assignee: MUTABILIS
    Inventors: Dmytro Atamanyuk, Vincent Gerusz, Francois Moreau, Vivien Henryon, Jerome Monbrun, Etienne Airiau
  • Publication number: 20150291636
    Abstract: The invention relates to compounds of formulae (Ia), (Ib) or (Ic) wherein, A1 and A2, identical or different, are H, (C1-C6) alkyl, (C1-C6) fluoroalkyl, (C2-C6) alkenyl, (C2-C6) alkynyl, (C1-C6) alkyl-ORa, (C1-C6) alkyl-SRa, (C1-C6) alkyl-NRaRb, ORa, SRa, NRaRb, or CORa; A3 is H, OH or form a carbonyl with A4; A4 is H, OH or form a carbonyl with A3; A5 is H, CRaRbOH, F, OH or forms a double bond with X in the case where X is CH; A6 is H or F; X is CH2, CHF, CF2, CHOH, O, S, NRa or a simple bond, or X is CH in the case where A5 forms with X a double bond; Y is P(O)(ORa)(ORb) or P(O)(ORa)(NRaRb); V is O or S; A7 is H, (C1-C6) alkyl, (C1-C6) fluoroalkyl, (C2-C6) alkenyl, (C2-C6) alkynyl or (C1-C6) alkyl-ORa; A8 is OH or H, Ra and Rb, identical or different, are H, (C1-C6) alkyl, (C1-C6) fluoroalkyl, (C1-C6) alkyl-OH or (C1-C6) alkyl-O—(C1-C6) alkyl; and their addition salts thereof with acids and bases, their preparation and their use in the antibacterial prevention and therapy, used alone or in association with
    Type: Application
    Filed: October 28, 2013
    Publication date: October 15, 2015
    Applicant: LABORATOIRE BIODIM
    Inventors: Dmytro Atamanyuk, Vincent Gerusz, Francois Moreau, Vivien Henryon, Jerome Monbrun, Etienne Airiau
  • Patent number: 8822706
    Abstract: The invention relates to a method for preparing 2-hydroxybutyrolactone (2HBL) from a compound or its salt or its oligomers, said compound fitting formula (I) CH3—S—CH2CH2CR1R2R3 Wherein R1 represents H R2 represents a group selected from OH; OR4 and OCOR4 wherein R4 represents a group selected from linear, cyclic, alicyclic or branches alkyl groups having from 1 to 10 carbon atoms, and aryl groups having from 6 to 10 carbon atoms, optionally substituted with substituent(s) selected from linear or branched alkyl groups having from 1 to 10 carbon atoms, halogens and hydroxyl, amino, nitro and alkoxy groups having from 1 to 10 carbon atoms; and OSiRR?R? wherein R, R? and R? are selected independently of each other from linear, cyclic, alicyclic or branched alkyl groups having from 1 to 10 carbon atoms, aryl groups having from 6 to 10 carbon atoms, optionally substituted with substituent(s) selected from linear or branched alkyl groups having from 1 to 10 carbon atoms, or R1 and R2 represent together ?O, R3 r
    Type: Grant
    Filed: October 17, 2011
    Date of Patent: September 2, 2014
    Assignee: Adisseo France S.A.S.
    Inventors: Vivien Henryon, Jerome Monbrun
  • Publication number: 20130204016
    Abstract: The invention relates to a method for preparing 2-hydroxybutyrolactone (2HBL) from a compound or its salt or its oligomers, said compound fitting formula (I) CH3—S—CH2CH2CR1R2R3 Wherein R1 represents H R2 represents a group selected from OH; OR4 and OCOR4 wherein R4 represents a group selected from linear, cyclic, alicyclic or branches alkyl groups having from 1 to 10 carbon atoms, and aryl groups having from 6 to 10 carbon atoms, optionally substituted with substituent(s) selected from linear or branched alkyl groups having from 1 to 10 carbon atoms, halogens and hydroxyl, amino, nitro and alkoxy groups having from 1 to 10 carbon atoms; and OSiRR?R? wherein R, R? and R? are selected independently of each other from linear, cyclic, alicyclic or branched alkyl groups having from 1 to 10 carbon atoms, aryl groups having from 6 to 10 carbon atoms, optionally substituted with substituent(s) selected from linear or branched alkyl groups having from 1 to 10 carbon atoms, or R1 and R2 represent together ?O, R3
    Type: Application
    Filed: October 17, 2011
    Publication date: August 8, 2013
    Applicant: ADISSEO FRANCE S.A.S.
    Inventors: Vivien Henryon, Jerome Monbrun
  • Publication number: 20110009649
    Abstract: A method for preparing 2-(n-butyl)-5-nitrobenzofuran from 1-halo-4-nitrobenzene, characterized in that 1-hexen-3-ol is reacted, and then the product is subject to a Claisen rearrangement, followed by catalytic intramolecular cyclization.
    Type: Application
    Filed: April 4, 2008
    Publication date: January 13, 2011
    Inventors: Thierry Durand, Ousmanne Diouf, Stephane Lemeune, Jean-Francois Marcoux, Vivien Henryon, Jerome Monbrun, Madeleine Delamare