Patents by Inventor Jerome Rossert

Jerome Rossert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CRISPR-CAS9 Modified CD34+ Human Hematopoietic Stem and Progenitor Cells and Uses Thereof
    Publication number: 20250041349
    Abstract: Provided herein, in some embodiments, are methods and compositions for treatment of subjects with ?-thalassemia and subjects with severe sickle cell disease using autologous CRISPR-Cas9 modified CD34+ human hematopoietic stem and progenitor cells.
    Type: Application
    Filed: October 28, 2024
    Publication date: February 6, 2025
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Ewelina Morawa, Tirtha Chakraborty, Ante Sven Lundberg, Tony Ho, Laura Sandler, Brenda Eustace, Jerome Rossert, Robert Kauffman
  • CRISPR-CAS9 modified CD34+ human hematopoietic stem and progenitor cells and uses thereof
    Patent number: 12161674
    Abstract: Provided herein, in some embodiments, are methods and compositions for treatment of subjects with ?-thalassemia and subjects with severe sickle cell disease using autologous CRISPR-Cas9 modified CD34+ human hematopoietic stem and progenitor cells.
    Type: Grant
    Filed: December 5, 2018
    Date of Patent: December 10, 2024
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Ewelina Morawa, Tirtha Chakraborty, Ante Sven Lundberg, Tony Ho, Laura Sandler, Brenda Eustace, Jerome Rossert, Robert Kauffman
  • CRISPR-CAS9 MODIFIED CD34+ HUMAN HEMATOPOIETIC STEM AND PROGENITOR CELLS AND USES THEREOF
    Publication number: 20200384033
    Abstract: Provided herein, in some embodiments, are methods and compositions for treatment of subjects with ?-thalassemia and subjects with severe sickle cell disease using autologous CRISPR-Cas9 modified CD34+ human hematopoietic stem and progenitor cells.
    Type: Application
    Filed: December 5, 2018
    Publication date: December 10, 2020
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Ewelina Morawa, Tirtha Chakraborty, Ante Sven Lundberg, Tony Ho, Laura Sandler, Brenda Eustace, Jerome Rossert, Robert Kauffman
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OF CAST NEPHROPATHY AND RELATED CONDITIONS
    Publication number: 20180057534
    Abstract: Provided are novel peptides of Formula SEQ ID No. 1: (SEQ?ID?No.?1) J1CysX1X2X3X4X5X6ProX7ThrCysJ2J3(J4)s(J5)t; pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are which are effective inhibitors of light chains to uromodulin.
    Type: Application
    Filed: March 8, 2017
    Publication date: March 1, 2018
    Inventors: Roger Leger, Gilles Dube, Marie-Elaine Caruso, Jerome Rossert
  • Compositions and methods for the treatment of cast nephropathy and related conditions
    Patent number: 9611297
    Abstract: Provided are novel peptides of Formula SEQ ID No. 1: J1CysX1X2X3X4X5X6ProX7ThrCysJ2J3(J4)s(J5)t;?? (SEQ ID No. 1) pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are effective inhibitors of light chains to uromodulin.
    Type: Grant
    Filed: December 2, 2016
    Date of Patent: April 4, 2017
    Assignee: Thrasos Therapeutics Inc.
    Inventors: Roger Leger, Gilles Dube, Marie-Elaine Caruso, Jerome Rossert