Abstract: A bone regeneration membrane comprising: a dense layer made of resorbable polymer, said dense layer having first and second opposite surfaces and being adapted to form a barrier to cells and soft tissues, a nanofibrillar layer made of resorbable polymer and attached to the first surface of the dense layer, said nanofibrillar layer comprising fibers having a diameter of nanometer size, said fibers being interlaced so as to present an average pore size greater than 10 ?m to allow cell permeability and bone tissue regeneration, the nanofibrillar layer having a permeability ? between 0.4*10-9 m2 and 11*10-9 m2, preferably between 1*10-9 m2 and 4*10-9 m2, in particular substantially of 2*10-9 m2.

Abstract: A bone regeneration membrane comprising: a dense layer made of resorbable polymer, said dense layer having first and second opposite surfaces and being adapted to form a barrier to cells and soft tissues, a nanofibrillar layer made of resorbable polymer and attached to the first surface of the dense layer, said nanofibrillar layer comprising fibers having a diameter of nanometer size, said fibers being interlaced so as to present an average pore size greater than 10 ?m to allow cell permeability and bone tissue regeneration, the nanofibrillar layer having a permeability ? between 0.4*10-9 m2 and 11*10-9 m2, preferably between 1*10-9 m2 and 4*10-9 m2, in particular substantially of 2*10-9 m2.

Abstract: A method for forming nanofiber web comprises the steps of: mixing (21) polymeric material with a solvent to obtain a liquid mixture having a viscosity above a predetermined shear viscosity value at room temperature; feeding (23) a spray nozzle with said mixture; projecting (25) said mixture through said nozzle with a gas jet, wherein the projected polymeric material solidifies and forms nanofibers; depositing (27) said nanofibers on a collecting surface to form said nanofiber web.

Abstract: The invention relates to a coating for medical devices. The coating comprises a specific copolymer of which the composition may be adjusted such as to achieve an excellent adhesion to a wide range of surfaces. The coating may further comprise an additive, such as a biologically active agent, which may be released in vivo in a controlled manner, as the degradability of the coating may also be adjusted to a predetermined rate. The invention further relates to a process for applying the coating to a surface and to a medical device comprising the coating.

Abstract: The invention relates to a coating for medical devices. The coating comprises a specific copolymer of which the composition may be adjusted such as to achieve an excellent adhesion to a wide range of surfaces. The coating may further comprise an additive, such as a biologically active agent, which may be released in vivo in a controlled manner, as the degradability of the coating may also be adjusted to a predetermined rate. The invention further relates to a process for applying the coating to a surface and to a medical device comprising the coating.

Abstract: The invention relates to a coating for medical devices. The coating comprises a specific copolymer of which the composition may be adjusted such as to achieve an excellent adhesion to a wide range of surfaces. The coating may further comprise an additive, such as a biologically active agent, which may be released in vivo in a controlled manner, as the degradability of the coating may also be adjusted to a predetermined rate. The invention further relates to a process for applying the coating to a surface and to a medical device comprising the coating.