Patents by Inventor Jeronimo Bravo Sicilia

Jeronimo Bravo Sicilia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cell penetrating peptides with improved internalization properties
    Patent number: 10947276
    Abstract: A method for delivering a cargo molecule into a cell is described that comprises linking a cargo molecule to a cell penetrating peptide. Chimeric constructs comprising cell penetrating moieties are also provided.
    Type: Grant
    Filed: December 18, 2017
    Date of Patent: March 16, 2021
    Assignees: SORBONNE UNIVERSITÉ, INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MEDICALE), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, PEP-THERAPY
    Inventors: Angelita Rebollo, Jesus Maria Fominaya Gutierrez, Jeronimo Bravo Sicilia, Sophie Lebel Binay, Leticia Dominguez Berrocal
  • CELL PENETRATING PEPTIDES WITH IMPROVED INTERNALIZATION PROPERTIES
    Publication number: 20190337985
    Abstract: The invention relates to a method for delivering a cargo molecule into a cell, which method comprises linking said cargo molecule to a cell penetrating peptide. The chimeric constructs comprising such cell penetrating moieties are encompassed.
    Type: Application
    Filed: December 18, 2017
    Publication date: November 7, 2019
    Inventors: ANGELITA REBOLLO, JESUS MARIA FOMINAYA GUTIERREZ, JERONIMO BRAVO SICILIA, SOPHIE LEBEL BINAY, LETICIA DOMINGUEZ BERROCAL
  • PRO-APOPTOTIC SET AND PP2A PEPTIDES
    Publication number: 20180066241
    Abstract: The invention provide chimeric peptides comprising a chimeric peptide comprising a cell-penetrating peptide linked to a pro-apoptotic peptide, wherein the pro-apoptotic peptide is derived from, or consists of, a portion of PP2A protein that binds a SET protein or is derived from, or consists of, a portion of the SET protein that binds PP2A protein.
    Type: Application
    Filed: March 31, 2016
    Publication date: March 8, 2018
    Inventors: Angelita Rebollo Garcia, Jeronimo Bravo Sicilia, Jesus Maria Fominaya Gutierrez, Etienne Waelkens, Veerle Janssens
  • Cell-penetrating peptides
    Patent number: 9644001
    Abstract: A vector that includes a cell-penetrating peptide linked to a therapeutic agent. The therapeutic agent can be a cytotoxic agent, an anti-viral agent, an anti-bacterial agent, or an anti-parasitic agent.
    Type: Grant
    Filed: May 26, 2016
    Date of Patent: May 9, 2017
    Assignees: Universite Pierre Et Marie Curie (Paris 6), Institut Curie
    Inventors: Angelita Rebollo Garcia, Fariba Nemati, Didier Decaudin, Jeronimo Bravo Sicilia, Jesus Maria Fominaya Gutierrez
  • CELL-PENETRATING PEPTIDES
    Publication number: 20160257713
    Abstract: The invention relates to a cell-penetrating peptide, optionally linked to a pro-apoptotic peptide, useful as pro-apoptotic agents, for inhibition of in vitro cell proliferation and for treatment of tumors.
    Type: Application
    Filed: May 26, 2016
    Publication date: September 8, 2016
    Inventors: Angelita Rebollo Garcia, Fariba Nemati, Didier Decaudin, Jeronimo Bravo Sicilia, Jesus Maria Fominaya Gutierrez
  • Cell-penetrating peptides
    Patent number: 9353155
    Abstract: A cell-penetrating peptide is described. Also described is a pro-apoptotic agent including the cell-penetrating peptide and a pro-apoptotic peptide linked thereto. The pro-apoptotic agent is useful for inhibition of in vitro cell proliferation and for treatment of tumors.
    Type: Grant
    Filed: December 27, 2012
    Date of Patent: May 31, 2016
    Assignees: Universite Pierre et Marie Curie (Paris 6), Institute Curie
    Inventors: Angelita Rebollo Garcia, Fariba Nemati, Didier Decaudin, Jeronimo Bravo Sicilia, Jesus Maria Fominaya Gutierrez
  • CELL-PENETRATING PEPTIDES
    Publication number: 20140364376
    Abstract: The invention relates to a cell-penetrating peptide, optionally linked to a pro-apoptotic peptide, useful as pro-apoptotic agents, for inhibition of in vitro cell proliferation and for treatment of tumors.
    Type: Application
    Filed: December 27, 2012
    Publication date: December 11, 2014
    Inventors: Angelita Rebollo Garcia, Fariba Nemati, Didier Decaudin, Jeronimo Bravo Sicilia, Jesus Maria Fominaya Gutierrez