Patents by Inventor Jerry Adams

Jerry Adams has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10730907
    Abstract: A compound of Formula (I) wherein Y1, Y2, X1, X2, R1, R2, R3, R4, R5, R6, R8, and R9 are as defined herein; and pharmaceutically acceptable salts and tautomers thereof, compositions, combinations and medicaments containing said compounds and processes for their preparation. The invention also relates to the use of said compounds, combinations, compositions and medicaments, in the treatment of diseases in which modulation of STING (Stimulator of Interferon Genes) is beneficial, for example inflammation, allergic and autoimmune diseases, infectious diseases, cancer, pre-cancerous syndromes and as vaccine adjuvants.
    Type: Grant
    Filed: July 26, 2019
    Date of Patent: August 4, 2020
    Assignee: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Jerry Adams, Yiqian Lian
  • Publication number: 20200002370
    Abstract: A compound of Formula (I) wherein Y1, Y2, X1, X2, R1, R2, R3, R4, R5, R6, R8, and R9 are as defined herein; and pharmaceutically acceptable salts and tautomers thereof, compositions, combinations and medicaments containing said compounds and processes for their preparation. The invention also relates to the use of said compounds, combinations, compositions and medicaments, in the treatment of diseases in which modulation of STING (Stimulator of Interferon Genes) is beneficial, for example inflammation, allergic and autoimmune diseases, infectious diseases, cancer, pre-cancerous syndromes and as vaccine adjuvants.
    Type: Application
    Filed: July 26, 2019
    Publication date: January 2, 2020
    Inventors: Jerry ADAMS, Yiqian Lian
  • Patent number: 10364266
    Abstract: A compound of Formula (I) wherein Y1, Y2, X1, X2, R1, R2, R3, R4, R5, R6, R8, and R9 are as defined herein; and pharmaceutically acceptable salts and tautomers thereof, compositions, combinations and medicaments containing said compounds and processes for their preparation. The invention also relates to the use of said compounds, combinations, compositions and medicaments, in the treatment of diseases in which modulation of STING (Stimulator of Interferon Genes) is beneficial, for example inflammation, allergic and autoimmune diseases, infectious diseases, cancer, pre-cancerous syndromes and as vaccine adjuvants.
    Type: Grant
    Filed: May 15, 2018
    Date of Patent: July 30, 2019
    Assignee: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Jerry Adams, Yiqian Lian
  • Publication number: 20180258132
    Abstract: A compound of Formula (I) wherein Y1, Y2, X1, X2, R1, R2, R3, R4, R5, R6, R8, and R9 are as defined herein; and pharmaceutically acceptable salts and tautomers thereof, compositions, combinations and medicaments containing said compounds and processes for their preparation. The invention also relates to the use of said compounds, combinations, compositions and medicaments, in the treatment of diseases in which modulation of STING (Stimulator of Interferon Genes) is beneficial, for example inflammation, allergic and autoimmune diseases, infectious diseases, cancer, pre-cancerous syndromes and as vaccine adjuvants.
    Type: Application
    Filed: May 15, 2018
    Publication date: September 13, 2018
    Inventors: Jerry ADAMS, Yiqian LIAN
  • Patent number: 9994607
    Abstract: A compound of Formula (I) wherein Y1, Y2, X1, X2, R1, R2, R3, R4, R5, R6, R8, and R9 are as defined herein; and pharmaceutically acceptable salts and tautomers thereof, compositions, combinations and medicaments containing said compounds and processes for their preparation. The invention also relates to the use of said compounds, combinations, compositions and medicaments, in the treatment of diseases in which modulation of STING (Stimulator of Interferon Genes) is beneficial, for example inflammation, allergic and autoimmune diseases, infectious diseases, cancer, pre-cancerous syndromes and as vaccine adjuvants.
    Type: Grant
    Filed: May 4, 2017
    Date of Patent: June 12, 2018
    Assignee: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Jerry Adams, Yiqian Lian
  • Publication number: 20170233430
    Abstract: A compound of Formula (I) wherein Y1, Y2, X1, X2, R1, R2, R3, R4, R5, R6, R8, and R9 are as defined herein; and pharmaceutically acceptable salts and tautomers thereof, compositions, combinations and medicaments containing said compounds and processes for their preparation. The invention also relates to the use of said compounds, combinations, compositions and medicaments, in the treatment of diseases in which modulation of STING (Stimulator of Interferon Genes) is beneficial, for example inflammation, allergic and autoimmune diseases, infectious diseases, cancer, pre-cancerous syndromes and as vaccine adjuvants.
    Type: Application
    Filed: May 4, 2017
    Publication date: August 17, 2017
    Inventors: Jerry Adams, Yiqian Lian
  • Patent number: 9718848
    Abstract: A compound of Formula (I) wherein Y1, Y2, X1, X2, R1, R2, R3, R4, R5, R6, R8, and R9 are as defined herein; and pharmaceutically acceptable salts and tautomers thereof, compositions, combinations and medicaments containing said compounds and processes for their preparation. The invention also relates to the use of said compounds, combinations, compositions and medicaments, in the treatment of diseases in which modulation of STING (Stimulator of Interferon Genes) is beneficial, for example inflammation, allergic and autoimmune diseases, infectious diseases, cancer, pre-cancerous syndromes and as vaccine adjuvants.
    Type: Grant
    Filed: December 5, 2016
    Date of Patent: August 1, 2017
    Assignee: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Jerry Adams, Kevin J. Duffy, Yiqian Lian
  • Publication number: 20170158724
    Abstract: A compound of Formula (I) wherein Y1, Y2, X1, X2, R1, R2, R3, R4, R5, R6, R8, and R9 are as defined herein; and pharmaceutically acceptable salts and tautomers thereof, compositions, combinations and medicaments containing said compounds and processes for their preparation. The invention also relates to the use of said compounds, combinations, compositions and medicaments, in the treatment of diseases in which modulation of STING (Stimulator of Interferon Genes) is beneficial, for example inflammation, allergic and autoimmune diseases, infectious diseases, cancer, pre-cancerous syndromes and as vaccine adjuvants.
    Type: Application
    Filed: December 5, 2016
    Publication date: June 8, 2017
    Inventors: Jerry ADAMS, Kevin J. DUFFY, Yiqian LIAN
  • Publication number: 20110269774
    Abstract: The present invention relates to a compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R11, R12, R13, Q, Z, and p are as described herein. Compounds of the present invention are useful for the treatment of cancers.
    Type: Application
    Filed: April 29, 2011
    Publication date: November 3, 2011
    Inventors: Jerry ADAMS, Thomas Faitg, Neil Johnson, Jiri Kasparec, Hong Lin, Mark Mellinger, Xin Peng, Ren Xie
  • Patent number: 7582439
    Abstract: The present invention relates generally to novel molecules capable of, inter alia, modulating apoptosis in mammalian cells and to genetic sequences encoding same. More particularly, the present invention relates to a novel member of the Bcl-2 family of proteins, referred to herein as “Bim”, and to genetic sequences encoding same. The molecules of the present invention are useful, for example, in therapy, diagnosis, antibody generation and as a screening tool for therapeutic agents capable of modulating physiological cell death or survival and/or modulating cell cycle entry.
    Type: Grant
    Filed: April 24, 2006
    Date of Patent: September 1, 2009
    Assignee: The Walter and Eliza Hall Institute of Medical Research
    Inventors: Suzanne Cory, Jerry Adams, David C. S. Huang, Liam O'Connor, Andreas Strasser, Hamsa Puthalakath, Lorraine O'Reilly
  • Publication number: 20080081808
    Abstract: The present invention relates to a compound represented by Formula (I): and pharmaceutically acceptable salts. Compounds of the present invention inhibit Aurora kinase, making them especially suitable for the treatment of a number of diseases, including solid tumor cancers and hematological cancers.
    Type: Application
    Filed: September 14, 2007
    Publication date: April 3, 2008
    Inventors: Martha Sarpong, Nicholas Adams, Jeffrey Axten, Amita Chaudhari, Dashyant Dhanak, Toshihiro Hamajima, Kenneth Newlander, Cynthia Parrish, Jerry Adams, Domingos Silva, Jun Tang
  • Publication number: 20080032969
    Abstract: Novel substituted 2,4,8-trisubstituted-8H-pyrido[2,3-d]pyrimidin-7-one compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.
    Type: Application
    Filed: August 16, 2007
    Publication date: February 7, 2008
    Inventors: Jerry Adams, Jefrrey Boehm, Ralph Hall, Qi Jin, Jiri Kasparec, Domingos Silva, John Taggart
  • Publication number: 20080033170
    Abstract: Novel substituted 2,4,8-trisubstituted-8H-pyrido[2,3-d]pyrimidin-7-one compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.
    Type: Application
    Filed: August 16, 2007
    Publication date: February 7, 2008
    Inventors: Jerry Adams, Jeffrey Boehm, Ralph Hall, Qi Jin, Jiri Kasparec, Domingos Silva, John Taggart
  • Publication number: 20080017126
    Abstract: A system and method for the sorting of livestock including a livestock processing station, a computer network system, and a trolley system. The livestock processing station confines the individual livestock, allowing individual livestock data to be collected and analyzed. The computer network system includes a first computer for data input at the livestock processing station and a second computer coupled to the first computer via a computer network, the second computer for storing and analyzing individual livestock data and assigning livestock to pens. The trolley system is controlled by the computer network system for transporting livestock from the livestock processing station to the assigned livestock pen. Such system includes a plurality of trolley cars for containing livestock and a conveyor system coupled to the plurality of trolley cars for transporting livestock to the assign livestock pen.
    Type: Application
    Filed: September 26, 2007
    Publication date: January 24, 2008
    Inventors: William Adams, Jerry Adams
  • Publication number: 20070293489
    Abstract: Pyrazolo-pyrimidine derivatives are described herein. The described invention also includes methods of making such derivatives as well as methods of using the same in the treatment of diseases.
    Type: Application
    Filed: May 11, 2007
    Publication date: December 20, 2007
    Inventors: Jerry Adams, Jiri Kasparec, Domingos Silva, Catherine Yuan
  • Publication number: 20070238743
    Abstract: Novel substituted pyrimido[4,5-d]pyrimidin-2-one compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.
    Type: Application
    Filed: December 20, 2006
    Publication date: October 11, 2007
    Inventors: Jerry Adams, Jeffrey Boehm, John Taggart, Ralph Hall
  • Publication number: 20070167467
    Abstract: Novel substituted pyrimido[4,5-d]pyrimidin-2-one compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.
    Type: Application
    Filed: December 20, 2006
    Publication date: July 19, 2007
    Inventors: Jerry Adams, Jeffrey Boehm, John Taggart, Ralph Hall
  • Publication number: 20070014584
    Abstract: System and methods may calibrate an AC rms voltage applied to a coronode of a charging device to achieve a predefined operating current at a target value of DC shield voltage. The target value of DC shield voltage may be set to be substantially below an over-voltage condition. System and methods may use a calibration routine that may determine a minimum AC voltage required to achieve the target value of DC shield voltage. Systems and methods may alternatively, or additionally, sense current and adjust the applied voltage to obtain a target current.
    Type: Application
    Filed: July 13, 2005
    Publication date: January 18, 2007
    Applicant: XEROX CORPORATION
    Inventors: Gerald Fletcher, John O'Brien, Bruce Parks, Eliud Robles-Flores, Alfred Claflin, Jerry Adams
  • Publication number: 20070010534
    Abstract: The present invention is directed to novel compounds of Formula (I) for use in the treatment of diseases, in a mammal, in which inappropriate, excessive or undesirable angiogenesis has occurred and/or where excessive Tie2 receptor activity has occurred.
    Type: Application
    Filed: September 19, 2006
    Publication date: January 11, 2007
    Inventors: Jerry Adams, Neil Johnson, Jeffrey Murray
  • Publication number: 20060290331
    Abstract: An electrophotographic document production device having a transformerless high voltage power supply located distal to its load and a transformer at the point of load.
    Type: Application
    Filed: June 22, 2005
    Publication date: December 28, 2006
    Applicant: XEROX CORPORATION
    Inventors: William Harris, Jerry Adams