Patents by Inventor Jerry B. Evarts

Jerry B. Evarts has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10414737
    Abstract: A process for the synthesis of quinazolinone containing compounds which may be useful for the treatment of cancer, is hereby disclosed. In addition, compound intermediates relating to these processes are also disclosed.
    Type: Grant
    Filed: July 2, 2018
    Date of Patent: September 17, 2019
    Assignee: Gilead Sciences, Inc.
    Inventors: Stacy Bremner, Jerry B. Evarts, Keiko Sujino, Duong Tran, Dragos Vizitiu
  • Publication number: 20190031626
    Abstract: A process for the synthesis of quinazolinone containing compounds which may be useful for the treatment of cancer, is hereby disclosed. In addition, compound intermediates relating to these processes are also disclosed.
    Type: Application
    Filed: July 2, 2018
    Publication date: January 31, 2019
    Inventors: Stacy BREMNER, Jerry B. EVARTS, Keiko SUJINO, Duong TRAN, Dragos VIZITIU
  • Patent number: 9469643
    Abstract: Polymorphs of (S)-2-(1-(9H-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one, compositions thereof, methods for their preparation, and methods for their use are disclosed.
    Type: Grant
    Filed: September 22, 2014
    Date of Patent: October 18, 2016
    Assignee: Gilead Calistoga, LLC.
    Inventors: Ernest Carra, Michael Gerber, Bing Shi, Keiko Sujino, Duong Tran, Fang Wang, Jerry B. Evarts
  • Publication number: 20150080572
    Abstract: Polymorphs of (S)-2-(1-(9H-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one, compositions thereof, methods for their preparation, and methods for their use are disclosed.
    Type: Application
    Filed: September 22, 2014
    Publication date: March 19, 2015
    Applicant: GILEAD CALISTOGA LLC
    Inventors: Ernest CARRA, Michael GERBER, Bing SHI, Keiko SUJINO, Duong TRAN, Fang WANG, Jerry B. EVARTS
  • Patent number: 8865730
    Abstract: Polymorphs of (S)-2-(1-(9H-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one, compositions thereof, methods for their preparation, and methods for their use are disclosed.
    Type: Grant
    Filed: March 5, 2013
    Date of Patent: October 21, 2014
    Assignee: Gilead Calistoga LLC
    Inventors: Ernest Carra, Michael Gerber, Bing Shi, Keiko Sujino, Duong Tran, Fang Wang, Jerry B. Evarts
  • Publication number: 20140235643
    Abstract: The invention provides methods that relate to a novel therapeutic strategy for the treatment of cancer and inflammatory diseases. In particular, the method comprises administration of a compound of Formula I, or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition comprising such compound admixed with at least one pharmaceutically acceptable excipient.
    Type: Application
    Filed: October 4, 2012
    Publication date: August 21, 2014
    Inventors: Jerry B. Evarts, Kamal D. Puri, Roger G. Ulrich, Edward A. Kesicki, Thomas Judge
  • Publication number: 20130344138
    Abstract: The invention provides methods that relate to a novel therapeutic strategy for the treatment of hematological malignancies and inflammatory diseases. In particular, the method comprises administration of a compound of formula I, or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition comprising such compound admixed with at least one pharmaceutically acceptable excipient.
    Type: Application
    Filed: August 28, 2013
    Publication date: December 26, 2013
    Applicant: GILEAD CALISTOGA LLC
    Inventors: Kamal D. PURI, Jerry B. EVARTS, Brian LANNUTTI, Neill GIESE
  • Patent number: 8546409
    Abstract: The invention provides methods that relate to a novel therapeutic strategy for the treatment of hematological malignancies and inflammatory diseases. In particular, the method comprises administration of a compound of formula I, or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition comprising such compound admixed with at least one pharmaceutically acceptable excipient.
    Type: Grant
    Filed: April 20, 2010
    Date of Patent: October 1, 2013
    Assignee: Gilead Calistoga LLC
    Inventors: Kamal D. Puri, Jerry B. Evarts, Brian Lannutti, Neill Giese
  • Patent number: 8440677
    Abstract: The invention provides compounds, compositions and methods to treat certain inflammatory conditions and/or oncology by administering a compound that inhibits PI3K isoforms, particularly the delta isoform. It further provides specific stereoisomers of a compound useful for these methods. In particular, the compound is an optically active atropisomer of 2-((6-amino-9H-purin-9-yl)methyl)-5-methyl-3-o-tolylquinazolin-4(3H)-one.
    Type: Grant
    Filed: March 24, 2010
    Date of Patent: May 14, 2013
    Assignee: Gilead Calistoga LLC
    Inventors: Jerry B. Evarts, Roger G. Ulrich
  • Publication number: 20110044942
    Abstract: The invention provides methods that relate to a novel therapeutic strategy for the treatment of hematological malignancies and inflammatory diseases. In particular, the method comprises administration of a compound of formula I, or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition comprising such compound admixed with at least one pharmaceutically acceptable excipient.
    Type: Application
    Filed: April 20, 2010
    Publication date: February 24, 2011
    Inventors: Kamal D. PURI, Jerry B. Evarts, Brian Lannutti, Neill A. Giese
  • Publication number: 20100249155
    Abstract: The invention provides compounds, compositions and methods to treat certain inflammatory conditions and/or oncology by administering a compound that inhibits PI3K isoforms, particularly the delta isoform. It further provides specific stereoisomers of a compound useful for these methods. In particular, the compound is an optically active atropisomer of 2-((6-amino-9H-purin-9-yl)methyl)-5-methyl-3-o-tolylquinazolin-4(3H)-one.
    Type: Application
    Filed: March 24, 2010
    Publication date: September 30, 2010
    Inventors: Jerry B. Evarts, Roger G. Ulrich
  • Patent number: 7501535
    Abstract: The invention provides novel six and seven-carbon termini-differentiated polypropionate stereotetrads and stereopentads useful in syntheses of natural products. The invention also provides a novel alkylative sulfenylation-desulfonylation process that efficiently transforms enantiopure epoxyvinyl sulfones to syn and anti dienylsulfides in two operations.
    Type: Grant
    Filed: September 15, 2003
    Date of Patent: March 10, 2009
    Assignee: Purdue Research Foundation
    Inventors: Philip L. Fuchs, David J. Meyers, Eduardo Torres, Taesik Park, In C. Kim, Yuzhong Chen, Douglas Lantrip, Jerry B. Evarts, Jr.
  • Publication number: 20040138485
    Abstract: The invention provides novel six and seven-carbon termini-differentiated polypropionate stereotetrads and stereopentads useful in syntheses of natural products. The invention also provides a novel alkylative sulfenylation-desulfonylation process that efficiently transforms enantiopure epoxyvinyl sulfones to syn and anti dienylsulfides in two operations.
    Type: Application
    Filed: September 15, 2003
    Publication date: July 15, 2004
    Inventors: Philip L. Fuchs, David J. Meyers, Eduardo Torres, Taesik Park, In C. Kim, Yuzhong Chen, Douglas Lantrip, Jerry B. Evarts