Abstract: Disclosed is a composition of cytoplasm stain for use in differentiation of cell nuclei from cell cytoplasmic components and differentiation of specific cytoplasm components by tinctorial contrast. Specifically, the invention relates to stain composition utilized as a counter stain in the hematoxylin and eosin procedure for use in histological and cytological microscopic evaluation of tissue and cells. The stain composition includes eosin-Y as the sole dye in the composition, a propylene glycol solvent and an organic buffer.

Abstract: A composition for use in staining histological and cytological tissue and cell samples which includes a buffer component in a staining solution. Specifically, the invention relates to stains and methods of producing stains for histological and cytological microscopic evaluation of tissue and cells. The buffer component is adjusted to a pH range below the isoelectric point (IEP) necessary to charge the protein or protein moiety of interest. The composition of a dye and solvent with a buffer component is particularly useful in obtaining controlled staining specificity of tissue elements or components, increasing reproducibility of the staining results, and increasing shelf-life of the staining reagent.

Abstract: A composition of two cytoplasm stains for use in differentiation of cell nuclei from cell cytoplasmic components and differentiation of specific cytoplasm components by tinctorial contrast. Specifically, the invention relates to two stain compositions utilized as a counter stain in the hematoxylin and eosin procedure for use in histological and cytological microscopic evaluation of tissue and cells. In one embodiment, the composition includes eosin-Y as the sole dye in the composition, and a propylene glycol solvent and an organic buffer. In another embodiment, the composition includes a mixture of eosin-Y and phloxine-B as the sole dye, also in a propylene glycol solvent and an organic buffer.

Abstract: The invention relates to a unit for the treatment of histological samples. The unit comprises a treatment chamber (1), a device (2) for supplying and removing treatment agents (3, 3?, 3?) to and from the treatment chamber (1), and a control system (4) for the performance of the treatment. The aim of the invention is to develop the unit in such a way that the need to carry out different treatments is taken into account in an economical manner. Towards this end, at least one other treatment chamber (5) is provided, by means of which treatments can be carried out independently from the first treatment chamber (1), the device (2) and the control system (4) also co-operating with that other treatment chamber (5).

Abstract: The invention relates to a buffer system comprising maleic acid and maleic acid dipotassium salt, for use with formalin-containing fixative solutions. The buffer system is soluble/miscible in dehydration solutions including alcohols, ketones, and monomethyl ethers, thereby preventing formation of precipitates in fluid lines and valve systems of automated tissue processors.

Abstract: The invention relates to a unit for the treatment of histological samples. The unit comprises a treatment chamber (1), a device (2) for supplying and removing treatment agents (3, 3?, 3?) to and from the treatment chamber (1), and a control system (4) for the performance of the treatment. The aim of the invention is to develop the unit in such a way that the need to carry out different treatments is taken into account in an economical manner. Towards this end, at least one other treatment chamber (5) is provided, by means of which treatments can be carried out independently from the first treatment chamber (1), the device (2) and the control system (4) also co-operating with that other treatment chamber (5).