Abstract: The present disclosure relates to pharmaceutical compositions comprising enzymes or enzyme mixtures having lipolytic and other optional other activities and methods of use thereof to treat exocrine pancreatic insufficiency.

Abstract: A fluid wand closure assembly includes a receiving tube with a wand receiving aperture and a predetermined external surface configuration. A wand holder fits within and abuts the receiving tube. A ring is configured to complement the external surface configuration and to abut the wand holder. Tightening the ring against the wand holder causes the ring to abut the wand holder and causes the wand holder to abut the receiving tube and seal the closure.

Abstract: A fluid wand closure assembly includes a receiving tube with a wand receiving aperture and a predetermined external surface configuration. A wand holder fits within and abuts the receiving tube. A ring is configured to complement the external surface configuration and to abut the wand holder. Tightening the ring against the wand holder causes the ring to abut the wand holder and causes the wand holder to abut the receiving tube and seal the closure.

Abstract: The present disclosure relates to pharmaceutical compositions comprising enzymes or enzyme mixtures having lipolytic and other optional other activities and methods of use thereof to treat exocrine pancreatic insufficiency.

Abstract: The present invention provides anti-nerve growth factor (NGF) antibodies that contain an IgG4 constant region comprising a stabilizing hinge region mutation and wherein the antibodies exhibit an unexpectedly long serum half-life in cynomolgus monkeys. Pharmaceutical compositions comprising the anti-NGF antibodies, nucleic acids encoding the NGF antibodies, host cells for expressing the NGF antibodies and methods of using the antibodies for treating NGF-related diseases or conditions are also provided.

Abstract: The present invention provides anti-nerve growth factor (NGF) antibodies that contain an IgG4 constant region comprising a stabilizing hinge region mutation and wherein the antibodies exhibit an unexpectedly long serum half life in cynomolgus monkeys. Pharmaceutical compositions comprising the anti-NGF antibodies, nucleic acids encoding the NGF antibodies, host cells for expressing the NGF antibodies and methods of using the antibodies for treating NGF-related diseases or conditions are also provided.

Abstract: The present invention provides anti-nerve growth factor (NGF) antibodies that contain an IgG4 constant region comprising a stabilizing hinge region mutation and wherein the antibodies exhibit an unexpectedly long serum half life in cynomolgus monkeys. Pharmaceutical compositions comprising the anti-NGF antibodies, nucleic acids encoding the NGF antibodies, host cells for expressing the NGF antibodies and methods of using the antibodies for treating NGF-related diseases or conditions are also provided.

Abstract: The present invention provides anti-nerve growth factor (NGF) antibodies that contain an IgG4 constant region comprising a stabilizing hinge region mutation and wherein the antibodies exhibit an unexpectedly long serum half life in cynomolgus monkeys. Pharmaceutical compositions comprising the anti-NGF antibodies, nucleic acids encoding the NGF antibodies, host cells for expressing the NGF antibodies and methods of using the antibodies for treating NGF-related diseases or conditions are also provided.

Abstract: A method for processing a request for data in a plurality of database formats is described. The method may include accepting a request for data. A format of the data request may be assessed. The assessed format may be a sequential access data format, a direct access data format, or a relational data format. If the assessed format of the data request is in the sequential access data format or the direct access data format, the data request may be translated into a relational data format. A relational database architecture may process the data request. A result to the data request may be returned. The result may be returned in the assessed format of the data request.

Abstract: A tool for removing scuff marks from floors is connectable to a handle of standard floor tools. The tool includes an inflexible knob with a felt-type material covering. A user simply rubs the felt-type material against the scuffmark until the scuff mark is removed.

Abstract: A method for processing a request for data in a plurality of database formats is described. The method may include accepting a request for data. A format of the data request may be assessed. The assessed format may be a sequential access data format, a direct access data format, or a relational data format. If the assessed format of the data request is in the sequential access data format or the direct access data format, the data request may be translated into a relational data format. A relational database architecture may process the data request. A result to the data request may be returned. The result may be returned in the assessed format of the data request.

Abstract: Design and manufacture of floor covering webs for, design, manufacture and installation of, asymmetrical carpet tiles having a prominent design element not intersected by a tile edge. Bands or regions define “frames” around what will become central carpet tile areas so that design elements positioned within the frames will not be intersected by a tile edge and may also be at least a predetermined distance from each tile edge. Design elements also may be positioned differing distances from each of at least one pair of opposed tile edges.

Abstract: A carpet tile and tile cutting apparatus that produces a carpet tile with a removable cutout section defined by discontinuous slits and held in place by bridges. The apparatus includes a perimeter cutting assembly and retractable inner cutting assembly. The perimeter cutting assembly is used to cut the carpet tile and the inner cutting assembly simultaneously forms the discontinuous slits in the inner portion of the carpet tile. The inner cutting assembly can be engaged or disengaged during the carpet tile cutting process. The carpet tile is installed by severing the bridges and laying the border sections on the floor with dissimilar cutouts within the borders to create a visually interesting floor covering.

Abstract: A mouthpiece for a clarinet wherein the facing over which the reed is attached and which extends around the opening in the mouthpiece is uniquely curved to vary the gap between the reed and the facing and wherein the bore, which is of a preferred length, is provided with a tapered A-frame bridge adjacent the sound baffle of the mouthpiece.

Abstract: A cargo restraining device suitable for restraining barrel-shaped containers or drums is disclosed, which includes a platform, which is spaced from the underlying supporting surface or floor, by horizontal supporting members which extend the length of at least the flat portion of the platform, so as to provide a raised deck for the containers. At one end of the platform, an upright or vertical frame is connected to the supporting members, to prevent the containers from falling off the platform. The other end of the platform can be rounded over to define a snub-nose; or alternatively the other ends of the horizontal supporting members can project beyond the platform (which is otherwise flat) and be rounded into snub-nosed portions. In consequence, should the drums shift or move, whereby damage might ordinarily occur, the chimes or rims of the drums tend to flow around the snub-nose (or snub-noses if defined at the supporting members) without any significant damage.