Patents by Inventor Jerry L. Ruth

Jerry L. Ruth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Single-stranded labelled oligonucleotides of preselected sequences
    Patent number: 5817786
    Abstract: Substantially pure single-stranded oligonucleotides having a preselected sequence of not more than about 200 nucleotides, at least one of which is at a preselected position in the sequence and includes a base with a covalently attached linker arm containing or capable of binding at least one reporter group or solid support. A process for the chemical synthesis of the substantially pure single-stranded oligonucleotide and modified nucleosides useful in such synthesis are provided.
    Type: Grant
    Filed: March 10, 1997
    Date of Patent: October 6, 1998
    Assignee: Molecular Biosystems, Inc.
    Inventor: Jerry L. Ruth
  • Synthesis of single-stranded labelled oligonucleotides of preselected sequence
    Patent number: 5668266
    Abstract: Substantially pure single-stranded oligonucleotides having a preselected sequence of not more than about 200 nucleotides, at least one of which is at a preselected position in the sequence and includes a base with a covalently attached linker arm containing or capable of binding at least one reporter group or solid support. A process for the chemical synthesis of the substantially pure single-stranded oligonucleotide and modified nucleosides useful in such synthesis are provided.
    Type: Grant
    Filed: May 12, 1995
    Date of Patent: September 16, 1997
    Assignee: Syngene, Inc.
    Inventor: Jerry L. Ruth
  • Single-stranded labelled oligonucleotides of preselected sequence
    Patent number: 5541313
    Abstract: Substantially pure single-stranded oligonucleotides having a preselected sequence of not more than about 200 nucleotides, at least one of which is at a preselected position in the sequence and includes a base with a covalently attached linker arm containing or capable of binding at least one reporter group or solid support. A process for the chemical synthesis of the substantially pure single-stranded oligonucleotide and modified nucleosides useful in such synthesis are provided.
    Type: Grant
    Filed: November 9, 1994
    Date of Patent: July 30, 1996
    Assignee: Molecular Biosystems, Inc.
    Inventor: Jerry L. Ruth
  • Single-stranded labelled oligonucleotides, reactive monomers and methods of synthesis
    Patent number: 4948882
    Abstract: Substantially pure single-stranded oligonucleotides having a preselected sequence of not more than about 200 nucleotides, at least one of which is at a preselected position in the sequence and includes a base with a covalently attached linker arm containing or capable of binding at least one reporter group or solid support. A process for the chemical synthesis of the substantially pure single-stranded oligonucleotide and modified nucleosides useful in such synthesis are provided.
    Type: Grant
    Filed: May 4, 1987
    Date of Patent: August 14, 1990
    Assignee: Syngene, Inc.
    Inventor: Jerry L. Ruth
  • C-5 Substituted cytosine nucleosides
    Patent number: 4267171
    Abstract: C-5 Substituted cytosine nucleosides wherein the C-5 substituent is substituted alkyl, alkenyl or substituted alkenyl; and the pharmaceutically acceptable acid addition salts thereof, are useful as antiviral agents. A novel process for the preparation of the subject compounds is also disclosed.
    Type: Grant
    Filed: July 2, 1979
    Date of Patent: May 12, 1981
    Assignee: The Regents of the University of California
    Inventors: Donald E. Bergstrom, Jerry L. Ruth
  • C-5 Substituted uracil nucleosides
    Patent number: 4247544
    Abstract: Compounds of the formula ##STR1## wherein R.sub.o is --CH.dbd.CH--CH.sub.3 or --CH.dbd.CH--CF.sub.3 and R is .beta.-D-ribofuranosyl, .beta.-D-2-deoxyribofuranosyl or .beta.-D-arabinofuranosyl are useful as antiviral agents.
    Type: Grant
    Filed: July 2, 1979
    Date of Patent: January 27, 1981
    Assignee: The Regents of the University of California
    Inventors: Donald E. Bergstrom, Jerry L. Ruth