Patents by Inventor Jerry L. Slightom
Jerry L. Slightom has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20090325155Abstract: Disclosed are polynucleotides encoding polypeptides having Aureobasidin A synthetase activity and Aureobasidin A synthetase-like activity. The invention also provides methods for detecting AbA synthetase proteins and nucleic acids and AbA synthetase-like proteins and nucleic acids in cells, and method for producing AbA synthetase polypeptides.Type: ApplicationFiled: August 25, 2006Publication date: December 31, 2009Inventors: Ake P. Elhammer, Jerry L. Slightom, Brian P. Metzger
-
Publication number: 20040097718Abstract: The invention provides an isolated S. aureus ribosomal polypeptide S20, and the isolated polynucleotide molecules that encode them, vectors and host cells comprising such polynucleotide molecules and also methods for the identification of agents that effect ribosomal assembly.Type: ApplicationFiled: January 14, 2003Publication date: May 20, 2004Inventors: James D. Pearson, Jerry L. Slightom, John G. Chosay, Mark C. McCroskey, Dean L. Shinabarger, Sheri K Wilcox
-
Publication number: 20020164756Abstract: The invention provides an isolated S. aureus ribosomal polypeptide S16, and the isolated polynucleotide molecules that encode them, vectors and host cells comprising such polynucleotide molecules and also methods for the identification of agents that effect ribosomal assembly.Type: ApplicationFiled: July 19, 2001Publication date: November 7, 2002Inventors: Jerry L. Slightom, John G. Chosay, Dean L. Shinabarger, James D. Pearson
-
Patent number: 5998699Abstract: The present invention relates to the coat protein genes of Papaya Ringspot Virus Strain papaya ringspot (PRV-p), Watermelon Mosaic Virus II (WMVII), and Zucchini Yellow Mosaic Virus (ZYMV); to expression vectors which contain a coat protein gene for PVP-p, WMVII or ZYMV, and, additionally, the necessary genetic regulatory sequences needed for expression of a gene transferred into a plant; to bacterial or plant cells which are transformed with an expression vector containing the PVP-p, WMVII or ZYMV coat protein genes; to transgenic plants which are produced from plant cells transformed with an expression vector containing the coat protein gene from PVP-p, WMVII or ZYMV; and to a process of producing transgenic plants which have increased resistance to viral infection.Type: GrantFiled: December 19, 1994Date of Patent: December 7, 1999Assignees: Seminis Vegetable Seeds, Inc., Cornell Research Foundation, Inc.Inventors: Jerry L. Slightom, Hector D. Quemada, Dennis Gonsalves, Brigitte L'hostis
-
Patent number: 5877403Abstract: NIa protease genes of papaya ringspot virus strains FLA.83 W and USA P-type (HA attenuated) strain are provided.Type: GrantFiled: December 30, 1995Date of Patent: March 2, 1999Assignees: Seminis Vegetable Seeds, Inc., Cornell Research FoundationInventors: J. Russell McMaster, Maury L. Boeshore, David M. Tricoli, John F. Reynolds, Kim J. Carney, Jerry L. Slightom, Dennis Gonsalves
-
Patent number: 5824866Abstract: The sequence of the T.sub.L -DNA of Ri plasmids found in Agrobacterium rhizogenes strains HRI and A4 is disclosed. Sixteen open reading frames bounded by eukaryotic promoters, ribosome binding sites, and polyadenylation sites were found, five of which were observed to be transcripted in a developmentally and phenotypically regulated manner. The use of promoters and polyadenylation sites from pRi T.sub.L -DNA to control expression of heterologous foreign structural genes is taught, using as examples the structural genes for Phaseolus vulgaris storage protein (phaseolin), P. vulgaris lectin, a sweet protein (thaumatin), and Bacillus thuringiensis crystal protein. Vectors useful for manipulation of sequences of the structural genes and T-DNA are also provided.Type: GrantFiled: June 2, 1995Date of Patent: October 20, 1998Assignee: Mycogen Plant Science, Inc.Inventors: Jerry L. Slightom, David A. Tepfer
-
Patent number: 5623066Abstract: A DNA fragment which encodes the coat protein of cucumber mosaic virus strain c (CMV-C), the method of preparing it, its use to prepare transgenic plants and transgenic plants containing it are provided.Type: GrantFiled: December 28, 1994Date of Patent: April 22, 1997Assignee: Asgrow Seed CompanyInventors: Hector D. Quemada, Jerry L. Slightom
-
Patent number: 5591605Abstract: The invention provides genetically modified plant cells having a plant structural gene introduced and expressed therein under the control of a T-DNA promoter. In particular, the invention provides genetically modified plant cells having the phaseolin gene introduced and expressed therein under the control of a T-DNA promoter. Also provided are novel strains of bacteria containing and replicating T-DNA which has been modified to contain an inserted plant structural gene under the control of a T-DNA promoter. Further, the invention provides novel plasmids having the ability to replicate in E. coli and comprising T-DNA which has been modified to contain an inserted plant structural gene under the control of a T-DNA promoter.Type: GrantFiled: August 24, 1994Date of Patent: January 7, 1997Assignee: Mycogen Plant Science, Inc.Inventors: Timothy C. Hall, John D. Kemp, Jerry L. Slightom, Dennis W. Sutton
-
Patent number: 5543501Abstract: The sequence of the T.sub.L -DNA of Ri plasmids found in Agrobacterium rhizogenes strains HRI and A4 is disclosed. Sixteen open reading frames bounded by eukaryotic promoters, ribosome binding sites, and polyadenylation sites were found, five of which were observed to be transcripted in a developmentally and phenotypically regulated manner. The use of promoters and polyadenylation sites from pRi T.sub.L -DNA to control expression of heterologous foreign structural genes is taught, using as examples the structural genes for Phaseolus vulgaris storage protein (phaseolin), P. vulgaris lectin, a sweet protein (thaumatin), and Bacillus thuringiensis crystal protein. Vectors useful for manipulation of sequences of the structural genes and T-DNA are also provided.Type: GrantFiled: June 2, 1995Date of Patent: August 6, 1996Assignee: Mycogen Plant Science, Inc.Inventors: Jerry L. Slightom, David A. Tepfer
-
Patent number: 5504200Abstract: The phaseolin structural gene and promoter are disposed. Also disclosed are plasmids, bacteria, plant cells, plant tissue and plants containing the phaseolin promoter. The promoter finds use in the expression of heterologous plants genes, including the phaseolin gene, in transformed plant cells and plants.Type: GrantFiled: February 18, 1994Date of Patent: April 2, 1996Assignee: Mycogen Plant Science, Inc.Inventors: Timothy C. Hall, John D. Kemp, Jerry L. Slightom, Dennis W. Sutton, Norimoto Murai
-
Patent number: 5466792Abstract: The sequence of the T.sub.L -DNA of Ri plasmids found in Agrobacterium rhizogenes strains HRI and A4 is disclosed. Sixteen open reading frames bounded by eukaryotic promoters, ribosome binding sites, and polyadenylation sites were found, five of which were observed to be transcripted in a developmentally and phenotypically regulated manner. The use of promoters and polyadenylation sites from pRi T.sub.L -DNA to control expression of heterologous foreign structural genes is taught, using as examples the structural genes for Phaseolus vulgaris storage protein (phaseolin), P. vulgaris lectin, a sweet protein (thaumatin), and Bacillus thuringiensis crystal protein. Vectors useful for manipulation of sequences of the structural genes and T-DNA are also provided.Type: GrantFiled: November 8, 1994Date of Patent: November 14, 1995Assignee: Mycoen Plant Science, Inc.Inventors: Jerry L. Slightom, David A. Tepfer
-
Patent number: 5376543Abstract: A non-tissue culture process using Agrobacterium-mediated vectors to produce transgenic plants from seeds of such plants as the common bean and soybean.Type: GrantFiled: December 7, 1992Date of Patent: December 27, 1994Assignee: The University of ToledoInventors: Paula P. Chee, Stephen L. Goldman, Anne C. F. Graves, Jerry L. Slightom
-
Patent number: 5366887Abstract: The sequence of the T.sub.L -DNA of Ri plasmids found in Agrobacterium rhizogenes strains HRI and A4 is disclosed. Sixteen open reading frames bounded by eukaryotic promoters, ribosome binding sites, and polyadenylation sites were found, five of which were observed to be transcripted in a developmentally and phenotypically regulated manner. The use of promoters and polyadenylation sites from pRi T.sub.L -DNA to control expression of heterologous foreign structural genes is taught, using as examples the structural genes for Phaseolus vulgaris storage protein (phaseolin), P. vulgaris lectin, a sweet protein (thaumatin), and Bacillus thuringiensis crystal protein. Vectors useful for manipulation of sequences of the structural genes and T-DNA are also provided.Type: GrantFiled: January 25, 1993Date of Patent: November 22, 1994Assignee: Mycogen Plant Sciences, Inc.Inventors: Jerry L. Slightom, David A. Tepfer
-
Patent number: 5349128Abstract: The coat protein gene of cucumber mosaic virus strain WL (CMV-WL), the method of preparing it, its use to prepare transgenic plants and transgenic plants containing it are provided.Type: GrantFiled: January 28, 1993Date of Patent: September 20, 1994Assignee: The Upjohn CompanyInventors: Hector D. Quemada, Jerry L. Slightom, Dennis Gonsalves, Chris Kearney
-
Patent number: 5182200Abstract: The sequence of the T.sub.L -DNA of Ri plasmids found in Agrobacterium rhizogenes strains HRI and A4 is disclosed. Sixteen open reading frames bounded by eukaryotic promoters, ribosome binding sites, and polyadenylation sites were found, five of which were observed to be transcripted in a developmentally and phenotypically regulated manner. The use of promoters and polyadenylation sites from pRi T.sub.L -DNA to control expression of heterologous foreign structural genes is taught, using as examples the structural genes for Phaseolus vulgaris storage protein (phaseolin), P. vulgaris lectin, a sweet protein (thaumatin), and Bacillus thuringiensis crystal protein. Vectors useful for manipulation of sequences of the structural genes and T-DNA are also provided.Type: GrantFiled: April 22, 1985Date of Patent: January 26, 1993Assignee: Lubrizol Genetics, Inc.Inventors: Jerry L. Slightom, David A. Tepfer
-
Patent number: 5169770Abstract: A non-tissue culture process using Agrobacterium-mediated vectors to produce transgenic plants from seeds of such plants as the common bean and soybean.Type: GrantFiled: June 21, 1990Date of Patent: December 8, 1992Assignee: The University of ToledoInventors: Paula P. Chee, Stephen L. Goldman, Anne C. F. Graves, Jerry L. Slightom
-
Patent number: 5162601Abstract: The present invention relates to a recombinant multigene comprising a plurality of structural genes and a plurality of DNA sequences which encode peptide linkers. In the present invention, one of the structural genes encodes a protease, the DNA sequences encoding the peptide linkers are adjacent to the DNA sequences which encode the structural genes and the peptide linkers contain an amino acid sequence which the protease recognizes as a proteolytic cleavage site. The present invention additionally relates to transgenic plants which contain such a recombinant multigene transgene, host cells transformed with such a recombinant multigene, and transgenic animals which contain such a recombinant multigene transgene. Furthermore, the present invention relates to a method of producing a plurality of polypeptides in a host by incorporating and expressing in the host a such recombinant multigene.Type: GrantFiled: August 30, 1991Date of Patent: November 10, 1992Assignee: The Upjohn CompanyInventor: Jerry L. Slightom
-
Patent number: 5102796Abstract: The invention provides genetically modified plant cells having a plant structural gene introduced and expressed therein under the control of a T-DNA promoter. In particular, the invention provides genetically modified plant cells having the phaseolin gene introduced and expressed therein under the control of a T-DNA promoter. Also provided are novel strains of bacteria containing and replicating T-DNA which has been modified to contain an inserted plant structural gene under the control of a T-DNA promoter. Further, the invention provides plasmids having the ability to replicate in E. coli and comprising T-DNA which has been modified to contain an inserted plant structural gene under the control of a T-DNA promoter.Type: GrantFiled: January 20, 1988Date of Patent: April 7, 1992Assignee: Lubrizol Genetics, Inc.Inventors: Timothy C. Hall, John D. Kemp, Jerry L. Slightom, Dennis W. Sutton
-
Patent number: 5066587Abstract: A foreign substance, such as DNA, is injected into plant cells or tissue by a biological ballistical insertion technique. High pressure propellant gas is employed to accelerate the macroprojectile containing microprojectiles coated with the foreign substance. A movable macroprojectile stop mechanism is provided between an upper injection chamber and a lower sample-holding chamber so that multiple shots of macroprojectiles can be made without disrupting the vacuum in the lower chamber. The stop mechanism includes removable stopper plugs for stopping the macroprojectile. A vacuum seal is provided between the stop mechanism and the lower chamber.Type: GrantFiled: January 26, 1990Date of Patent: November 19, 1991Assignee: The Upjohn CompanyInventors: Lawrence D. Jones, Paul T. Frey, David D. Gleason, Paula P. Chee, Jerry L. Slightom