Patents by Inventor Jerry M. Buysse

Jerry M. Buysse has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions for and methods of treating acid-base disorders
    Patent number: 11992501
    Abstract: Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain nonabsorbable compositions and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons, the conjugate base of a strong acid and/or a strong acid from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.
    Type: Grant
    Filed: September 24, 2021
    Date of Patent: May 28, 2024
    Assignee: Renosis, Inc.
    Inventors: Gerrit Klaerner, Eric F. Connor, Randi K. Gbur, Matthew J. Kade, Paul H. Kierstead, Jerry M. Buysse, Michael J. Cope, Kalpesh N. Biyani, Son H. Nguyen, Scott M. Tabakman
  • Compositions for and method of treating acid-base disorders
    Patent number: 11986490
    Abstract: The present disclosure provides, inter alia, pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. In certain embodiments, the pharmaceutical compositions contain nonabsorbable pharmaceutical composition and may be used, for example, to treat eubicarbonatemic metabolic acidosis.
    Type: Grant
    Filed: February 23, 2022
    Date of Patent: May 21, 2024
    Assignee: Renosis, Inc.
    Inventors: Gerrit Klaerner, Jerry M. Buysse, Jun Shao, Dawn Parsell Otto
  • PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION
    Publication number: 20230405043
    Abstract: Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain crosslinked amine polymers and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons and/or chloride ions from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.
    Type: Application
    Filed: August 28, 2023
    Publication date: December 21, 2023
    Inventors: Gerrit Klaerner, Eric F. Connor, Randi K. Gbur, Matthew J. Kade, Paul H. Kierstead, Jerry M. Buysse, Michael J. Cope, Kalpesh N. Biyani, Son H. Nguyen, Scott M. Tabakman
  • Proton-binding polymers for oral administration
    Patent number: 11738041
    Abstract: Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain crosslinked amine polymers and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons and/or chloride ions from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.
    Type: Grant
    Filed: April 19, 2022
    Date of Patent: August 29, 2023
    Assignee: RENOSIS, INC.
    Inventors: Gerrit Klaerner, Eric F. Connor, Randi K. Gbur, Matthew J. Kade, Paul H. Kierstead, Jerry M. Buysse, Michael J. Cope, Kalpesh N. Biyani, Son H. Nguyen, Scott M. Tabakman
  • COMPOSITIONS FOR AND METHOD OF TREATING ACID-BASE DISORDERS
    Publication number: 20230031665
    Abstract: The present disclosure provides, inter alia, pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. In certain embodiments, the pharmaceutical compositions contain nonabsorbable pharmaceutical composition and may be used, for example, to treat eubicarbonatemic metabolic acidosis.
    Type: Application
    Filed: February 23, 2022
    Publication date: February 2, 2023
    Inventors: Gerrit KLAERNER, Jerry M. BUYSSE, Jun SHAO, Dawn Parsell OTTO
  • PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION
    Publication number: 20220339186
    Abstract: Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain crosslinked amine polymers and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons and/or chloride ions from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.
    Type: Application
    Filed: April 19, 2022
    Publication date: October 27, 2022
    Inventors: Gerrit KLAERNER, Eric F. CONNOR, Randi K. GBUR, Matthew J. KADE, Paul H. KIERSTEAD, Jerry M. BUYSSE, Michael J. COPE, Kalpesh N. BIYANI, Son H. NGUYEN, Scott M. TABAKMAN
  • HCl-binding compositions for and methods of treating acid-base disorders
    Patent number: 11406661
    Abstract: Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain nonabsorbable compositions and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons, the conjugate base of a strong acid and/or a strong acid from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.
    Type: Grant
    Filed: May 5, 2017
    Date of Patent: August 9, 2022
    Assignee: TRICIDA, INC.
    Inventors: Gerrit Klaerner, Eric F. Connor, Randi K. Gbur, Matthew J. Kade, Paul H. Kierstead, Jerry M. Buysse, Michael J. Cope, Kalpesh N. Biyani, Son H. Nguyen, Scott M. Tabakman
  • Proton-binding polymers for oral administration
    Patent number: 11311571
    Abstract: Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain crosslinked amine polymers and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons and/or chloride ions from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.
    Type: Grant
    Filed: December 10, 2015
    Date of Patent: April 26, 2022
    Assignee: TRICIDA, INC.
    Inventors: Gerrit Klaerner, Eric F. Connor, Randi K. Gbur, Matthew J. Kade, Paul H. Kierstead, Jerry M. Buysse, Michael J. Cope, Kalpesh N. Biyani, Son H. Nguyen, Scott M. Tabakman
  • PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION
    Publication number: 20220096534
    Abstract: Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain crosslinked amine polymers and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons and/or chloride ions from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.
    Type: Application
    Filed: December 9, 2021
    Publication date: March 31, 2022
    Inventors: Gerrit KLAERNER, Eric F. CONNOR, Randi K. GBUR, Matthew J. KADE, Paul H. KIERSTEAD, Jerry M. BUYSSE, Michael J. COPE, Kalpesh N. BIYANI, Son H. NGUYEN, Scott M. TABAKMAN
  • Compositions for and method of treating acid-base disorders
    Patent number: 11266684
    Abstract: The present disclosure provides, inter alia, pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. In certain embodiments, the pharmaceutical compositions contain nonabsorbable pharmaceutical composition and may be used, for example, to treat eubicarbonatemic metabolic acidosis.
    Type: Grant
    Filed: November 3, 2018
    Date of Patent: March 8, 2022
    Assignee: Tricida, Inc.
    Inventors: Gerrit Klaerner, Jerry M. Buysse, Jun Shao, Dawn Parsell Otto
  • COMPOSITIONS FOR AND METHODS OF TREATING ACID-BASE DISORDERS
    Publication number: 20220062328
    Abstract: Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain nonabsorbable compositions and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons, the conjugate base of a strong acid and/or a strong acid from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.
    Type: Application
    Filed: September 24, 2021
    Publication date: March 3, 2022
    Inventors: Gerrit KLAERNER, Eric F. CONNOR, Randi K. GBUR, Matthew J. KADE, Paul H. KIERSTEAD, Jerry M. BUYSSE, Michael J. COPE, Kalpesh N. BIYANI, Son H. NGUYEN, Scott M. TABAKMAN
  • Proton-binding polymers for oral administration
    Patent number: 11197887
    Abstract: Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain crosslinked amine polymers and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons and/or chloride ions from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.
    Type: Grant
    Filed: August 16, 2019
    Date of Patent: December 14, 2021
    Assignee: TRICIDA, INC.
    Inventors: Gerrit Klaerner, Eric F. Connor, Randi K. Gbur, Matthew J. Kade, Paul H. Kierstead, Jerry M. Buysse, Michael J. Cope, Kalpesh N. Biyani, Son H. Nguyen, Scott M. Tabakman
  • COMPOSITIONS FOR TREATING ACID-BASE DISORDERS
    Publication number: 20210205351
    Abstract: Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain nonabsorbable compositions and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons, the conjugate base of a strong acid and/or a strong acid from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.
    Type: Application
    Filed: March 4, 2021
    Publication date: July 8, 2021
    Inventors: Gerrit KLAERNER, Eric F. CONNOR, Randi K. GBUR, Matthew J. KADE, Paul H. KIERSTEAD, Jerry M. BUYSSE, Michael J. COPE, Kalpesh N. BIYANI, Son H. NGUYEN, Scott M. TABAKMAN
  • METHOD OF TREATING ACID-BASE DISORDERS
    Publication number: 20210187011
    Abstract: The present disclosure provides, inter alia, pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. In certain embodiments, the pharmaceutical compositions contain nonabsorbable compositions and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons, the conjugate base of a strong acid and/or a strong acid from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.
    Type: Application
    Filed: November 3, 2018
    Publication date: June 24, 2021
    Inventors: Gerrit KLAERNER, Jerry M. BUYSSE, Jun SHAO, Dawn Parsell OTTO
  • COMPOSITIONS FOR AND METHOD OF TREATING ACID-BASE DISORDERS
    Publication number: 20200289551
    Abstract: The present disclosure provides, inter alia, pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. In certain embodiments, the pharmaceutical compositions contain nonabsorbable pharmaceutical composition and may be used, for example, to treat eubicarbonatemic metabolic acidosis.
    Type: Application
    Filed: November 3, 2018
    Publication date: September 17, 2020
    Inventors: Gerrit KLAERNER, Jerry M. BUYSSE, Jun SHAO, Dawn Parsell OTTO
  • PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION
    Publication number: 20200206260
    Abstract: Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain crosslinked amine polymers and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons and/or chloride ions from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.
    Type: Application
    Filed: August 16, 2019
    Publication date: July 2, 2020
    Inventors: Gerrit KLAERNER, Eric F. CONNOR, Randi K. GBUR, Matthew J. KADE, Paul H. KIERSTEAD, Jerry M. BUYSSE, Michael J. COPE, Kalpesh N. BIYANI, Son H. NGUYEN, Scott M. TABAKMAN
  • ION BINDING POLYMERS AND USES THEREOF
    Publication number: 20200085856
    Abstract: The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides compositions comprising potassium binding polymers and pharmaceutical compositions thereof. Methods of use of the polymeric and pharmaceutical compositions for therapeutic and/or prophylactic benefits are disclosed herein. Examples of these methods include the treatment of hyperkalemia, such as hyperkalemia caused by renal failure and/or the use of hyperkalemia causing drugs.
    Type: Application
    Filed: November 25, 2019
    Publication date: March 19, 2020
    Inventors: Dominique Charmot, Han-Ting Chang, Gerrit Klaerner, Jerry M. Buysse, Mingjun Liu
  • COMPOSITIONS FOR AND METHODS OF TREATING ACID-BASE DISORDERS
    Publication number: 20200054669
    Abstract: Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain nonabsorbable compositions and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons, the conjugate base of a strong acid and/or a strong acid from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.
    Type: Application
    Filed: May 5, 2017
    Publication date: February 20, 2020
    Inventors: Gerrit KLAERNER, Eric F. CONNOR, Randi K. GBUR, Matthew J. KADE, Paul H. KIERSTEAD, Jerry M. BUYSSE, Michael J. COPE, Kalpesh N. BIYANI, Son H. NGUYEN, Scott M. TABAKMAN
  • Ion binding polymers and uses thereof
    Patent number: 10485821
    Abstract: The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides compositions comprising potassium binding polymers and pharmaceutical compositions thereof. Methods of use of the polymeric and pharmaceutical compositions for therapeutic and/or prophylactic benefits are disclosed herein. Examples of these methods include the treatment of hyperkalemia, such as hyperkalemia caused by renal failure and/or the use of hyperkalemia causing drugs.
    Type: Grant
    Filed: July 14, 2016
    Date of Patent: November 26, 2019
    Assignee: Vifor (International) Ltd.
    Inventors: Dominique Charmot, Han-Ting Chang, Gerrit Klaerner, Jerry M. Buysse, Mingjun Liu
  • Proton-binding polymers for oral administration
    Patent number: 10391118
    Abstract: Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain crosslinked amine polymers and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons and/or chloride ions from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.
    Type: Grant
    Filed: June 7, 2018
    Date of Patent: August 27, 2019
    Assignee: TRICIDA, INC
    Inventors: Gerrit Klaerner, Eric F. Connor, Randi K. Gbur, Matthew J. Kade, Paul H. Kierstead, Jerry M. Buysse, Michael J. Cope, Kalpesh N. Biyani, Son H. Nguyen, Scott M. Tabakman