Abstract: Provided herein, inter alia, are compounds useful in improving cognitive function, memory and learning in both healthy and diseased subjects.

Abstract: There are provided compounds and methods for the detection of amyloids and treatment of diseases related to amyloids including Alzheimer's disease and other related amyloid-based neurodegenerative diseases.

Abstract: Improved resolution and detection of nanoparticles are achieved when a nanopore connecting liquid compartments in a device running on the Coulter principle is provided with fluid coatings such as lipid walls. Fluid lipid walls are made of a lipid bilayer, and preferably include lipid anchored mobile ligands as part of the lipid bilayer. By varying the nature and concentration of the mobile ligand in the lipid bilayer, multifunctional coatings of lipids are provided.

Abstract: There are provided compounds and methods for the detection of amyloids and treatment of diseases related to amyloids including Alzheimer's disease and other related amyloid-based neurodegenerative diseases.

Abstract: Provided herein is the design and synthesis of novel molecular rotor fluorophores useful for detection of amyloid or amyloid like proteins. The fluorophores are designed to exhibit enhanced fluorescence emission upon associating with amyloid or amyloid like proteins as compared to unbound compound. Also disclosed herein are the methods for treating of diseases associated with an amyloid or amyloid like proteins.

Abstract: A loading mechanism of a storage device for accommodating a hard drive has a loading body and a second supporting arm. The loading body includes a loading base, a first supporting arm extending from one end of the loading base, and an assembling part provided on the loading base. The second supporting arm is laterally and slidably connected to another end of the loading base, and is disposed correspondingly to the first supporting arm. One end of the second supporting arm includes a stand disposed on the loading base and a sliding member disposed on the stand. The sliding member has an elastic engaging part being able to detachably connect to the assembling part. Therefore, the goal of quickly replacing hard disk without using any screws can be achieved.

Abstract: Improved resolution and detection of nanoparticles are achieved when a nanopore connecting liquid compartments in a device running on the Coulter principle is provided with fluid lipid walls. The fluid lipid walls are made of a lipid bilayer, and preferably include lipid anchored mobile ligands as part of the lipid bilayer. By varying the nature and concentration of the mobile ligand in the lipid bilayer, multifunctional coatings of lipids are provided.

Abstract: Provided herein, inter alia, are compounds useful in improving cognitive function, memory and learning in both healthy and diseased subjects.

Abstract: There are provided compounds and methods for the detection of amyloids and treatment of diseases related to amyloids including Alzheimer's disease and other related amyloid-based neurodegenerative diseases.

Abstract: There are provided compounds and methods for the detection of amyloids and treatment of diseases related to amyloids including Alzheimer's disease and other related amyloid-based neurodegenerative diseases.

Abstract: Described herein are compositions and methods for treating or preventing a sexually transmitted infection in a subject

Abstract: The invention is in general directed to compounds and methods for diagnosing, preventing or alleviating the symptoms of amyloid-associated diseases, for example, neuronal diseases, such as, for example, Alzheimer's disease, methods of screening for compounds useful in preventing or alleviating the symptoms of amyloid-associated diseases, methods of diagnostic imaging of A-beta fibrils, and compounds and methods useful for studying normal or disease-associated cellular mechanisms relating to amyloid proteins.

Abstract: The invention pertains generally to novel compositions and methods for constructing chemically sensitive ion channels. The compositions and methods include, for example, novel gramicidin A derivatives and their use in constructing novel ion channels for use as biosensors.

Abstract: The invention is in general directed to acid-sensitive linkers, and methods of use thereof, such as, for example, in drug delivery methods.

Abstract: Described herein are compositions and methods for treating or preventing a sexually transmitted infection in a subject.

Abstract: Improved resolution and detection of nanoparticles are achieved when a nanopore connecting liquid compartments in a device running on the Coulter principle is provided with fluid lipid walls. The fluid lipid walls are made of a lipid bilayer, and preferably include lipid anchored mobile ligands as part of the lipid bilayer. By varying the nature and concentration of the mobile ligand in the lipid bilayer, multifunctional coatings of lipids are provided.

Abstract: There are provided compounds and methods for the detection and treatment of amyloid deposits and diseases and disorders characterized by amyloid deposits including Alzheimer's disease and related amyloid-based neurodegenerative disorders.

Abstract: Provided herein methods of maintaining an embryonic stem cell culture in an undifferentiated state, wherein the method includes culturing an embryonic stem cell on a rabbit feeder cell layer, wherein the rabbit feeder layer expresses a leukemia inhibitory factor (LIF) protein. Also provided are methods of maintaining an embryonic stem cell culture in an undifferentiated state, wherein the method includes culturing an embryonic stem cell in a culture medium comprising rabbit leukemia inhibitory factor (rbLIF) protein. Also provided are polynucleotide and amino acid sequences of a rabbit leukemia inhibitory factor protein (rbLIF).

Abstract: A computer implemented method, system, and/or computer program product manage advertisement placement across disparate advertisement media platforms. The disparate advertisement media platforms are each coupled to a respective monitoring application. The monitoring applications monitor activities occurring within their respective advertisement media. Data describing the monitored activities is input to a business intelligence core. In response to one or more of the monitoring applications detecting a real-time event related to a specific subject, the business intelligence core adjusts an amount of electronic advertisement in one or more of the disparate advertising media.

Abstract: A rechargeable battery product for a portable electronic device is disclosed. The case comprises a controller module detachably attached to a replaceable battery module. The battery module can be detached and charged from the controller module to provide continuous power to the device. The device can be powered simultaneously while recharging the battery module by connecting an external interface of the controller module with an external power source. The controller module further comprises an on/off switch that reduces the amount of power discharged from the battery when the portable electronic device is fully charged or when the battery is not in use and an indicator that indicates the remaining power of the battery module. The depleted battery module can be swapped with a new battery module to provide continuous power to the device for long time periods.