Abstract: The present disclosure relates to various anchoring assemblies, systems, and methods for a catheter delivered device or otherwise implantable biomedical sensors. In one instance the anchoring systems of the present disclosure are designed to be used in connection with a biomedical sensor configured to be placed in the various locations within the anatomy of a patient including: a junction of a renal vein and an inferior vena cava, a junction of a jugular vein branch and a subclavian vein branch, a junction of a brachiocephalic vein branch and a superior vena cava, or a junction of an iliac vein branch and an inferior vena cava. In one embodiment, an biomedical sensor and anchoring system can be implanted in an organ of a patient or in an organ to be transplanted within a patient.