Abstract: The present invention provides a method and devices for the treatment of hemorrhoids. The method involves the combined delivery of cryotherapy and medication therapy. The devices described provide cryotherapy for immediate relief of pain, itching, reduction of swelling, reduction of existing bleeding, shrinkage of hemorrhoidal tissue, and promotes healing of affective tissues. Subsequent medication release from these devices provides sustained healing and protracted relief of symptoms. The devices may be disposable and may be used externally or internally, and may include an invasive or non-invasive applicator.

Abstract: The present invention provides a disposable cryotherapy device for the treatment of hemorrhoids. The cryotherapy device includes a hollow rectal insert with a wall that defines a plurality of slots. The device further includes a sleeve with an open end such that the rectal insert can slide into the sleeve. The sleeve covers the slots defined by the wall of the rectal insert. A frozen healing medium is located within the hollow rectal insert and is preferably formulated to provide about 5 minutes of cooling prior to melting during treatment of hemorrhoids or rectal tissue. The rectal insert is substantially cylindrical in shape and has a rounded end. The disposable cryotherapy device is preferably individually packaged. In another embodiment, the disposable cryotherapy device is an external applicator.

Abstract: A two-piece rectal insert containing a coolant fluid. The rectal insert includes a one-piece tube for holding the fluid and a one-piece cap which seals against the tube. The tube and the cap have complementary sealing structures to prevent the coolant fluid from leaking from the insert. The cap has a ring to which a string is tied. The string is pulled to remove the insert from the rectum. The cap and a wing portion of the tube provide a stop to prevent the insert from going too far into the rectum.