Patents by Inventor Jesper F Lau

Jesper F Lau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160347812
    Abstract: The present invention relates to novel glucagon peptides, to the use of said glucagon peptides in therapy, to methods of treatment comprising administration of said glucagon peptides to patients in need thereof, and to the use of said glucagon peptides in the manufacture of medicaments. The glucagon peptides of the present invention are of particular interest in relation to the treatment of hyperglycemia, diabetes and obesity, as well as a variety of diseases or conditions associated with hyperglycemia, diabetes and obesity.
    Type: Application
    Filed: August 16, 2016
    Publication date: December 1, 2016
    Inventors: Jesper F. Lau, Thomas Kruse, Henning Thoegersen, Ulrich Sensfuss, Peter Kresten Nielsen
  • Patent number: 9486506
    Abstract: The present invention relates to novel glucagon peptides, to the use of said glucagon peptides in therapy, to methods of treatment comprising administration of said glucagon peptides to patients in need thereof, and to the use of said glucagon peptides in the manufacture of medicaments. The glucagon peptides of the present invention are of particular interest in relation to the treatment of hyperglycemia, diabetes and obesity, as well as a variety of diseases or conditions associated with hyperglycemia, diabetes and obesity.
    Type: Grant
    Filed: February 24, 2015
    Date of Patent: November 8, 2016
    Assignee: Novo Nordisk A/S
    Inventors: Jesper F. Lau, Thomas Kruse, Henning Thoegersen, Ulrich Sensfuss, Peter Kresten Nielsen
  • Patent number: 9486505
    Abstract: The present invention relates to novel glucagon peptides, to the use of said glucagon peptides in therapy, to methods of treatment comprising administration of said glucagon peptides to patients in need thereof, and to the use of said glucagon peptides in the manufacture of medicaments. The glucagon peptides of the present invention are of particular interest in relation to the treatment of hyperglycemia, diabetes and obesity, as well as a variety of diseases or conditions associated with hyperglycemia, diabetes and obesity.
    Type: Grant
    Filed: July 9, 2013
    Date of Patent: November 8, 2016
    Assignee: Novo Nordisk A/S
    Inventors: Jesper F. Lau, Thomas Kruse, Henning Thoegersen, Ulrich Sensfuss, Peter Kresten Nielsen
  • Patent number: 9474790
    Abstract: The invention relates to novel stable and protracted GLP-1/glucagon receptor co-agonists, to the use of said peptides in therapy, to methods of treatment comprising administration of said peptides to patients, and to the use of said peptides in the manufacture of medicaments.
    Type: Grant
    Filed: August 26, 2015
    Date of Patent: October 25, 2016
    Assignee: Novo Nordisk A/S
    Inventors: Ulrich Sensfuss, Thomas Kruse, Jesper F. Lau
  • Publication number: 20160271263
    Abstract: The present invention relates to novel peptide compounds which have an improved physical stability in solution and improved solubility at neutral pH, to the use of the compounds in therapy, to methods of treatment comprising administration of the compounds to patients in need thereof, and to the use of the compounds in the manufacture of medicaments. The compounds of the invention are of particular interest in relation to the treatment of hyperglycemia, diabetes and obesity, as well as a variety of diseases or conditions associated with hyperglycemia, diabetes and obesity.
    Type: Application
    Filed: May 16, 2016
    Publication date: September 22, 2016
    Inventors: Jesper F. Lau, Thomas Kruse, Lars Linderoth, Henning Thoegersen
  • Publication number: 20160102129
    Abstract: New GLP-1 derivatives, compositions thereof and their use in medicine.
    Type: Application
    Filed: October 9, 2015
    Publication date: April 14, 2016
    Inventors: Steffen Reedtz-Runge, Ulrich Sensfuss, Thomas Kruse, Jane Spetzler, Henning Thoegersen, Christian W. Tornoee, Jesper F. Lau
  • Publication number: 20160002311
    Abstract: The present invention relates to novel peptide compounds which have a protracted profile of action and improved solubility and stability, to the use of the compounds in therapy, to methods of treatment comprising administration of the compounds to patients in need thereof, and to the use of the compounds in the manufacture of medicaments. The compounds of the invention are of particular interest in relation to the treatment of hyperglycemia, diabetes and obesity, as well as a variety of diseases or conditions associated with hyperglycemia, diabetes and obesity.
    Type: Application
    Filed: August 17, 2015
    Publication date: January 7, 2016
    Inventors: Jesper F. Lau, Thomas Kruse, Lars Linderoth, Henning Thoegersen, Jacob Kofoed, Kirsten Dahl
  • Publication number: 20150374794
    Abstract: The invention relates to novel stable and protracted GLP-1/glucagon receptor co-agonists, to the use of said peptides in therapy, to methods of treatment comprising administration of said peptides to patients, and to the use of said peptides in the manufacture of medicaments.
    Type: Application
    Filed: August 26, 2015
    Publication date: December 31, 2015
    Inventors: Ulrich Sensfuss, Thomas Kruse, Jesper F. Lau
  • Publication number: 20150368313
    Abstract: The present invention relates to novel glucagon peptides with improved stability and solubility at neutral pH, to the use of the compounds in therapy, to methods of treatment comprising administration of the compounds to patients in need thereof, and to the use of the compounds in the manufacture of medicaments. The glucagon peptides of the invention are of particular interest in relation to the treatment of hyperglycemia, diabetes and obesity, as well as a variety of diseases or conditions associated with hyperglycemia, diabetes and obesity.
    Type: Application
    Filed: July 31, 2015
    Publication date: December 24, 2015
    Inventors: Jesper F. Lau, Thomas Kruse, Henning Thoegersen, Thomas N. Krogh, Ulrich Sensfuss
  • Publication number: 20150274801
    Abstract: The present invention relates to novel peptide compounds which have an improved physical stability in solution and improved solubility at neutral pH, to the use of the compounds in therapy, to methods of treatment comprising administration of the compounds to patients in need thereof, and to the use of the compounds in the manufacture of medicaments. The compounds of the invention are of particular interest in relation to the treatment of hyperglycemia, diabetes and obesity, as well as a variety of diseases or conditions associated with hyperglycemia, diabetes and obesity.
    Type: Application
    Filed: June 15, 2015
    Publication date: October 1, 2015
    Inventors: Jesper F. Lau, Thomas Kruse, Lars Linderoth, Henning Thoegersen
  • Publication number: 20150182594
    Abstract: The present invention relates to novel glucagon peptides, to the use of said glucagon peptides in therapy, to methods of treatment comprising administration of said glucagon peptides to patients in need thereof, and to the use of said glucagon peptides in the manufacture of medicaments. The glucagon peptides of the present invention are of particular interest in relation to the treatment of hyperglycemia, diabetes and obesity, as well as a variety of diseases or conditions associated with hyperglycemia, diabetes and obesity.
    Type: Application
    Filed: February 24, 2015
    Publication date: July 2, 2015
    Inventors: Jesper F. Lau, Thomas Kruse, Henning Thoegersen, Ulrich Sensfuss, Peter Kresten Nielsen
  • Patent number: 8835379
    Abstract: Acylated CGRP compounds with a linker have prolonged action and are valuable as medicaments.
    Type: Grant
    Filed: October 27, 2010
    Date of Patent: September 16, 2014
    Assignee: Novo Nordisk A/S
    Inventors: Anette Sams Nielsen, Thomas Kruse, Janos Tibor Kodra, Jesper F. Lau, Jacob Kofoed, Kirsten Raun, Cecilia Nilsson
  • Publication number: 20140031278
    Abstract: The present invention relates to novel glucagon peptides with improved stability and solubility at neutral pH, to the use of the compounds in therapy, to methods of treatment comprising administration of the compounds to patients in need thereof, and to the use of the compounds in the manufacture of medicaments. The glucagon peptides of the invention are of particular interest in relation to the treatment of hyperglycemia, diabetes and obesity, as well as a variety of diseases or conditions associated with hyperglycemia, diabetes and obesity.
    Type: Application
    Filed: March 28, 2012
    Publication date: January 30, 2014
    Applicant: NOVO NORDISK A/S
    Inventors: Jesper F. Lau, Thomas Kruse, Henning Thoegersen, Thomas Nylandsted Krogh, Ulrich Sensfuss
  • Publication number: 20130288958
    Abstract: The present invention relates to novel glucagon peptides, to the use of said glucagon peptides in therapy, to methods of treatment comprising administration of said glucagon peptides to patients in need thereof, and to the use of said glucagon peptides in the manufacture of medicaments. The glucagon peptides of the present invention are of particular interest in relation to the treatment of hyperglycemia, diabetes and obesity, as well as a variety of diseases or conditions associated with hyperglycemia, diabetes and obesity.
    Type: Application
    Filed: July 9, 2013
    Publication date: October 31, 2013
    Inventors: Jesper F. Lau, Thomas Kruse, Henning Thoegersen, Ulrich Sensfuss, Peter Kresten Nielsen
  • Patent number: 8541368
    Abstract: The present invention relates to novel glucagon peptides, to the use of said glucagon peptides in therapy, to methods of treatment comprising administration of said glucagon peptides to patients in need thereof, and to the use of said glucagon peptides in the manufacture of medicaments. The glucagon peptides of the present invention are of particular interest in relation to the treatment of hyperglycemia, diabetes and obesity, as well as a variety of diseases or conditions associated with hyperglycemia, diabetes and obesity.
    Type: Grant
    Filed: September 21, 2012
    Date of Patent: September 24, 2013
    Assignee: Novo Nordisk A/S
    Inventors: Jesper F. Lau, Thomas Kruse, Henning Thoegersen, Ulrich Sensfuss, Peter Kresten Nielsen
  • Publication number: 20130143798
    Abstract: The present invention relates to novel peptide compounds which have an improved physical stability in solution and improved solubility at neutral pH, to the use of the compounds in therapy, to methods of treatment comprising administration of the compounds to patients in need thereof, and to the use of the compounds in the manufacture of medicaments. The compounds of the invention are of particular interest in relation to the treatment of hyperglycemia, diabetes and obesity, as well as a variety of diseases or conditions associated with hyperglycemia, diabetes and obesity.
    Type: Application
    Filed: March 28, 2011
    Publication date: June 6, 2013
    Applicant: NOVO NORDISK A/S
    Inventors: Jesper F. Lau, Thomas Kruse, Lars Linderoth, Henning Thoegersen
  • Publication number: 20130053310
    Abstract: The present invention relates to glucagon peptide agonists which have improved solubility and stability, to the use of the peptides in therapy, to methods of treatment comprising administration of the peptides to patients in need thereof, and to the use of the peptides in the manufacture of medicaments. The glucagon peptides of the invention are of particular interest in relation to the treatment of hypoglycemia, diabetes and obesity, as well as a variety of diseases or conditions associated with hypoglycemia, diabetes and obesity.
    Type: Application
    Filed: March 28, 2011
    Publication date: February 28, 2013
    Applicant: NOVO NORDISK A/S
    Inventors: Jesper F. Lau, Thomas Kruse
  • Publication number: 20130035285
    Abstract: The present invention relates to novel peptide compounds which have a protracted profile of action and improved solubility and stability, to the use of the compounds in therapy, to methods of treatment comprising administration of the compounds to patients in need thereof, and to the use of the compounds in the manufacture of medicaments. The compounds of the invention are of particular interest in relation to the treatment of hyperglycemia, diabetes and obesity, as well as a variety of diseases or conditions associated with hyperglycemia, diabetes and obesity.
    Type: Application
    Filed: March 28, 2011
    Publication date: February 7, 2013
    Applicant: Novo Nordisk A/S
    Inventors: Jesper F. Lau, Thomas Kruse, Lars Linderoth, Henning Thoegersen, Jacob Kofoed, Kirsten Dahl
  • Publication number: 20120245083
    Abstract: Acylated CGRP compounds with a linker have prolonged action and are valuable as medicaments.
    Type: Application
    Filed: October 27, 2010
    Publication date: September 27, 2012
    Applicant: Novo Nordisk A/S
    Inventors: Anette Sams Nielsen, Thomas Kruse, Janos Tibor Kodra, Jesper F. Lau, Jacob Kofoed, Kirsten Raun, Cecilia Nilsson
  • Patent number: RE45670
    Abstract: This invention relates to aryl carbonyl derivatives which are activators of glucokinase which may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial.
    Type: Grant
    Filed: December 20, 2013
    Date of Patent: September 15, 2015
    Assignee: NOVO NORDISK A/S
    Inventors: Dharma Rao Polisetti, Janos Tibor Kodra, Jesper F. Lau, Paw Bloch, Mustafa Guzel, Santhosh Chidambareswaran Kalpathy, Adnan M. M. Mjalli, Robert Carl Andrews, Govindan Subramanian, Michael Ankersen, Per Vedso, Anthony Murray, Lone Jeppesen, Jesper Lau