Patents by Inventor Jesper Tegner

Jesper Tegner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYSTEMS AND METHODS FOR REVERSE ENGINEERING MODELS OF BIOLOGICAL NETWORKS
    Publication number: 20130311159
    Abstract: The present invention provides methods and accompanying computer-based systems and computer-executable code stored on a computer-readable medium for constructing a model of a biological network. The invention further provides methods for performing sensitivity analysis on a biological network and for identifying major regulators of species in the network and of the network as a whole. In addition, the invention provides methods for identifying targets of a perturbation such as that resulting from exposure to a compound or an environmental change. The invention further provides methods for identifying phenotypic mediators that contribute to differences in phenotypes of biological systems.
    Type: Application
    Filed: July 29, 2013
    Publication date: November 21, 2013
    Applicant: TRUSTEES OF BOSTON UNIVERSITY
    Inventors: Timothy S. Gardner, James J. Collins, Diego di Bernardo, Jesper Tegner, Man Kit Stephen Yeung
  • METHODS FOR SCREENING AND TREATMENT INVOLVING THE GENES GYPC, AGPAT3, AGL, PVRL2, HMGB 3, HSDL2 AND/OR LDB2
    Publication number: 20100056608
    Abstract: The present invention relates to a method for identifying a compound as a candidate drug, comprising the steps a. bringing said compound into contact with a cell expressing the genes CYPC, AGPAT3, AGL, PVRL2, HMGB 3, HSDL2; and b. analyzing if said compound modulates the expression of at least one of said genes. It also relates to a method for identifying a compound as a candidate drug, comprising the steps a. bringing said compound into contact with a cell expressing the gene LDB2; and b. analyzing if said compound modulates the expression of LDB2. The invention further relates to genetically modified cells and animals useful in such methods and to methods for treatment of atherosclerosis, atherosclerosis-related diseases or inflammatory diseases, comprising the use of such identified compounds.
    Type: Application
    Filed: November 19, 2007
    Publication date: March 4, 2010
    Applicant: CLINICAL GENE NETWORKS AB
    Inventors: Johan Bjorkegren, Jesper Tegner
  • Systems and methods for reverse engineering models of biological networks
    Publication number: 20060293873
    Abstract: The present invention provides methods and accompanying computer-based systems and computer-executable code stored on a computer-readable medium for constructing a model of a biological network. The invention further provides methods for performing sensitivity analysis on a biological network and for identifying major regulators of species in the network and of the network as a whole. In addition, the invention provides methods for identifying targets of a perturbation such as that resulting from exposure to a compound or an environmental change. The invention further provides methods for identifying phenotypic mediators that contribute to differences in phenotypes of biological systems.
    Type: Application
    Filed: March 5, 2003
    Publication date: December 28, 2006
    Applicant: Trustees of Boston University
    Inventors: Timothy Gardner, James Collins, Diego di Bernardo, Jesper Tegner, Man Yeung