Abstract: An apparatus is provided that includes a torso and a plurality of legs, a first drive motor assembly secured to a first of the plurality of legs and to a first drive wheel, a second drive motor assembly secured to a second of the plurality of legs and to a second drive wheel, a motorized neck assembly coupling a head to the torso and providing a multi-directional rotational movement of the head, a rechargeable battery, a throttle switch to provide a throttle signal, a controller including one or more processors and memory devices, and an electrical steering position sensor configured to translate a mechanical steering input via manual rotation of the head into an electronic steering position signal that is communicated to the controller, wherein the controller is configured to selectively actuate at least one of the drive wheel motors based on the throttle signal and the steering position signal.

Abstract: An apparatus is provided that includes a torso and a plurality of legs, a first drive motor assembly secured to a first of the plurality of legs and to a first drive wheel, a second drive motor assembly secured to a second of the plurality of legs and to a second drive wheel, a motorized neck assembly coupling a head to the torso and providing a multi-directional rotational movement of the head, a rechargeable battery, a throttle switch to provide a throttle signal, a controller including one or more processors and memory devices, and an electrical steering position sensor configured to translate a mechanical steering input via manual rotation of the head into an electronic steering position signal that is communicated to the controller, wherein the controller is configured to selectively actuate at least one of the drive wheel motors based on the throttle signal and the steering position signal.

Abstract: An adapter connects to a valve to convert the valve to a uniform configuration for connection to a pump. In one application, a conventional Schrader or Presta valve has an adapter to convert the valve to a uniform configuration for connection to a pump. An attachment head of a pump engages and creates a seal with the adapter and has a release mechanism to disengage the attachment head from the adapter.

Abstract: A system for mixing the contents of a first container with the contents of a second container. The second container has a port assembly for receiving the first container. The port assembly has an actuator that is constructed to access the cavity of the first container during activation of the system and to allow fluid communication between the first container and the second container. The port assembly further includes a movable plug that provides a seal for the second container. The plug is configured to move axially relative to the actuator during activation of the system, thereby opening the seal of the second container and providing fluid communication between the first container and the second container.

Abstract: A medicament container having an opening that provides access to a cavity defined by the medicament container. A stopper is sealingly positioned within the opening of the medicament container and configured to be forced into the cavity to open the medicament container. The medicament container also includes a mating member configured to mate with a complementary receiver associated with a second container to connect the medicament container to a second container. The medicament container further includes a radial seal configured to engage and seal against an interior seal wall associated with a second container prior to the stopper being forced into the cavity defined by the medicament container. A system is also provided for establishing fluid communication between a first container and a second container. The system includes a first container (e.g., a medicament container) having a radial seal, a second container, and a port assembly.

Abstract: A port assembly for enabling contents of a first container to be mixed with contents of a second container. The port assembly has a port housing that is configured to receive a first container. The port assembly further includes an actuator axially fixed within a cavity of the port housing. The actuator is configured to open a first container by forcing a stopper sealing an opening of a first container into a cavity of a first container during activation.

Abstract: A rotational atherectomy device that includes an expandable head that can clean a blockage from vessel larger than its rest diameter, in which the drive shaft may rotate in two opposite directions and may have different abrasive characteristics for each rotation direction. In one direction, the head may be configured for cutting and/or slicing, which may be well suited to removing particularly soft blockage material. In the other direction, the head may be configured for grinding, scraping and/or sanding, which may be well suited to removing particularly hard blockage material. The head includes one or more arms that are pivotally or hingedly attached to the drive shaft. One or more abrasive elements are disposed on or are attached to the one or more arms. The abrasive elements have a cutting feature, such as a sharpened edge that cuts like a razor blade when the drive shaft is rotated in the “cutting” direction.

Abstract: The invention provides a rotational atherectomy system, device and method comprising a flexible, elongated, rotatable drive shaft with a pre-curved abrasive section disposed within a catheter that deforms the abrasive section to a substantially straight profile and, when the abrasive section is moved distally out of the catheter, the abrasive section resumes its pre-curved profile. Directional ablation is achieved by rotation of the drive shaft along its pre-curved axis as the abrasive section is urged against a portion of the lumen wall.

Abstract: A quick release bicycle saddle mounting bracket has a mounting portion for a bicycle saddle and a seat post mounting portion including a quick release cam lock. The quick release bicycle saddle mounting bracket may be installed or removed from a bicycle seat post without the use of tools.

Abstract: An adapter connects to a valve to convert the valve of a type, such as but not limited to Schrader or Presta, to a uniform configuration. An attachment head for engages and creates a seal with the adapter and has a release mechanism to disengage the attachment head from the adapter.

Abstract: A connector system for attaching accessories to a bicycle or other sporting good includes a base and a platform. The base is attached to a bicycle and the platform is attached to the accessory, and the base and the platform are held together by mechanical or magnetic forces.

Abstract: A system for mixing or reconstituting a drug contained in a first container with a diluent or fluid contained in a second container. The second container has a port docking assembly for engaging the first container. The first container is rotatable and axially slidable within the port docking assembly. The port docking assembly has an actuator to urge a stopper fluidly sealing the first container into the interior of the first container. The port docking assembly further includes a movable plug constructed to fluidly seal the second container in a first, docked position and to provide access to the interior of the second container in a second, activated position, whereby fluid communication between the first and second containers is provided when the first and second containers are in the second, activated position.

Abstract: The invention provides a rotational atherectomy system, device and method comprising a bi-directional drive shaft with a flexible ablation element disposed at the distal end of the drive shaft. The flexible ablation element comprises a first retracted position for insertion into vasculature and a second expanded position for ablation, i.e., cutting, sanding and/or grinding. The ablation element comprises more than one flexible finger or blade which allows changing, in certain embodiments, of curvature radius to fit inside a deployment catheter and/or enlarge to the diameter of larger lumens, up to at least 9 mm in diameter. Bi-directional rotation of the expanded ablation element allows cutting in one rotational direction and grinding and/or sanding in the opposite rotational direction.

Abstract: A system for mixing or reconstituting a drug contained in a first container with a diluent or fluid contained in a second container. The second container has a port docking assembly for engaging the first container. The first container is rotatable and axially slidable within the port docking assembly. The port docking assembly has an actuator to urge a stopper fluidly sealing the first container into the interior of the first container. The port docking assembly further includes a movable plug constructed to fluidly seal the second container in a first, docked position and to provide access to the interior of the second container in a second, activated position, whereby fluid communication between the first and second containers is provided when the first and second containers are in the second, activated position.

Abstract: A port assembly for connecting a first container to a second container and mixing the contents of the first container with the contents of the second container. The port assembly has a port housing that is configured to receive a first container. The port assembly further includes an actuator axially fixed within a cavity of the port housing. The actuator is configured to open the first container by forcing a stopper sealing an opening of the first container into a cavity of the first container during activation.

Abstract: A system for mixing the contents of a first container with the contents of a second container. The second container has a port assembly for receiving the first container. The port assembly has an actuator that is constructed to access the cavity of the first container during activation of the system and to allow fluid communication between the first container and the second container. The port assembly further includes a movable plug that provides a seal for the second container. The plug is configured to move axially relative to the actuator during activation of the system, thereby opening the seal of the second container and providing fluid communication between the first container and the second container.

Abstract: The invention provides a system, device and method for localized application of therapeutic substances within a biological conduit. One embodiment comprises a rotational atherectomy device having a flexible, elongated, rotatable, drive shaft having a lumen and with an eccentric enlarged abrading head having at least one application hole attached therethrough and in communication with a therapeutic agent delivery sheath and an operator-controlled actuator. The therapeutic substances may then spray radially outwardly from the application hole(s) on the eccentric abrading head during and/or after high-speed rotation of the head. Another embodiment comprises compartments in the abrading head that hold therapeutic agent(s) for release during high-speed rotation. In each case, the therapeutic substance(s) is delivered with radial forces resulting from high-speed orbital rotation of the eccentric abrading head, driving the therapeutic substance(s) into the conduit wall.

Abstract: A port assembly for enabling contents of a first container to be mixed with contents of a second container. The port assembly has a port housing that is configured to receive a first container. The port assembly further includes an actuator axially fixed within a cavity of the port housing. The actuator is configured to open a first container by forcing a stopper sealing an opening of a first container into a cavity of a first container during activation.

Abstract: A system for mixing the contents of a first container with the contents of a second container. The second container has a port assembly for receiving the first container. The port assembly has an actuator that is constructed to access the cavity of the first container during activation of the system and to allow fluid communication between the first container and the second container. The port assembly further includes a movable plug that provides a seal for the second container. The plug is configured to move axially relative to the actuator during activation of the system, thereby opening the seal of the second container and providing fluid communication between the first container and the second container.