Patents by Inventor Jesse D. Deere

Jesse D. Deere has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antisense antibacterial method and compound
    Patent number: 9534220
    Abstract: A method and antisense compound for inhibiting the growth of pathogenic bacterial cells are disclosed. The compound contains no more than 12 nucleotide bases and has a targeting nucleic acid sequence of no fewer than 10 bases in length that is complementary to a target sequence containing or within 10 bases, in a downstream direction, of the translational start codon of a bacterial mRNA that encodes a bacterial protein essential for bacterial replication. The compound binds to a target mRNA with a Tm of between 50° to 60° C. The relatively short antisense compounds are substantially more active than conventional antisense compounds having a targeting base sequence of 15 or more bases.
    Type: Grant
    Filed: November 19, 2012
    Date of Patent: January 3, 2017
    Assignee: Sarepta Therapeutics, Inc.
    Inventors: Bruce L. Geller, Jesse D. Deere, Patrick L. Iversen
  • Antisense antibacterial method and compound
    Patent number: 9487784
    Abstract: A method and antisense compound for inhibiting the growth of pathogenic bacterial cells are disclosed. The compound contains no more than 12 nucleotide bases and has a targeting nucleic acid sequence of no fewer than 10 bases in length that is complementary to a target sequence containing or within 10 bases, in a downstream direction, of the translational start codon of a bacterial mRNA that encodes a bacterial protein essential for bacterial replication. The compound binds to a target mRNA with a Tm of between 50° to 60° C. The relatively short antisense compounds are substantially more active than conventional antisense compounds having a targeting base sequence of 15 or more bases.
    Type: Grant
    Filed: November 19, 2012
    Date of Patent: November 8, 2016
    Assignee: Sarepta Therapeutics, Inc.
    Inventors: Bruce L. Geller, Jesse D. Deere, Patrick L. Iversen
  • ANTISENSE ANTIBACTERIAL METHOD AND COMPOUND
    Publication number: 20130289091
    Abstract: A method and antisense compound for inhibiting the growth of pathogenic bacterial cells are disclosed. The compound contains no more than 12 nucleotide bases and has a targeting nucleic acid sequence of no fewer than 10 bases in length that is complementary to a target sequence containing or within 10 bases, in a downstream direction, of the translational start codon of a bacterial mRNA that encodes a bacterial protein essential for bacterial replication. The compound binds to a target mRNA with a Tm of between 50° to 60° C. The relatively short antisense compounds are substantially more active than conventional antisense compounds having a targeting base sequence of 15 or more bases.
    Type: Application
    Filed: November 19, 2012
    Publication date: October 31, 2013
    Inventors: Bruce L. Geller, Jesse D. Deere, Patrick L. Iversen
  • Antisense antibacterial method and compound
    Patent number: 8314072
    Abstract: A method and antisense compound for inhibiting the growth of pathogenic bacterial cells are disclosed. The compound contains no more than 12 nucleotide bases and has a targeting nucleic acid sequence of no fewer than 10 bases in length that is complementary to a target sequence containing or within 10 bases, in a downstream direction, of the translational start codon of a bacterial mRNA that encodes a bacterial protein essential for bacterial replication. The compound binds to a target mRNA with a Tm of between 50° to 60° C. The relatively short antisense compounds are substantially more active than conventional antisense compounds having a targeting base sequence of 15 or more bases.
    Type: Grant
    Filed: July 1, 2005
    Date of Patent: November 20, 2012
    Assignee: AVI BioPharma, Inc.
    Inventors: Bruce L. Geller, Jesse D. Deere, Patrick L. Iversen
  • ANTISENSE ANTIBACTERIAL METHOD AND COMPOUND
    Publication number: 20100137408
    Abstract: A method and antisense compound for inhibiting the growth of pathogenic bacterial cells are disclosed. The compound contains no more than 12 nucleotide bases and has a targeting nucleic acid sequence of no fewer than 10 bases in length that is complementary to a target sequence containing or within 10 bases, in a downstream direction, of the translational start codon of a bacterial mRNA that encodes a bacterial protein essential for bacterial replication. The compound binds to a target mRNA with a Tm of between 50° to 60° C. The relatively short antisense compounds are substantially more active than conventional antisense compounds having a targeting base sequence of 15 or more bases.
    Type: Application
    Filed: November 5, 2009
    Publication date: June 3, 2010
    Inventors: Bruce L. Geller, Jesse D. Deere, Patrick L. Iversen, Dwight D. Weller
  • Antisense antibacterial method and compound
    Patent number: 7625873
    Abstract: A method and antisense compound for inhibiting the growth of pathogenic bacterial cells are disclosed. The compound contains no more than 12 nucleotide bases and has a targeting nucleic acid sequence of no fewer than 10 bases in length that is complementary to a target sequence containing or within 10 bases, in a downstream direction, of the translational start codon of a bacterial mRNA that encodes a bacterial protein essential for bacterial replication. The compound binds to a target mRNA with a Tm of between 50° to 60° C. The relatively short antisense compounds are substantially more active than conventional antisense compounds having a targeting base sequence of 15 or more bases.
    Type: Grant
    Filed: May 10, 2006
    Date of Patent: December 1, 2009
    Assignee: AVI BioPharma, Inc.
    Inventors: Bruce L. Geller, Jesse D. Deere, Patrick L. Iversen, Dwight D. Weller