Patents by Inventor Jesse Donovan

Jesse Donovan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of monitoring RNase L activity
    Patent number: 11859234
    Abstract: The present disclosure relates, in general, to a method for generating chimeric DNA derived from RNase L cleavage products in a sample, and detection of such RNase L cleavage products for diagnosis and treatment of inflammation and infection in a subject.
    Type: Grant
    Filed: May 5, 2017
    Date of Patent: January 2, 2024
    Assignee: THE TRUSTEES OF PRINCETON UNIVERSITY
    Inventors: Alexei Korennykh, Jesse Donovan
  • Reporter construct and biosensor for interferon second messenger 2-5A
    Patent number: 11667949
    Abstract: The present disclosure relates, in general, to a fusion protein construct comprising RNase L and a split reporter system, and methods of using the reporter for detecting 2?-5? linked oligoadenylates (2-5A) and double stranded RNA in vivo.
    Type: Grant
    Filed: February 15, 2019
    Date of Patent: June 6, 2023
    Assignee: THE TRUSTEES OF PRINCETON UNIVERSITY
    Inventors: Alexei Korennykh, Alisha Chitrakar, Jesse Donovan
  • Reporter Construct and Biosensor for Interferon Second Messenger 2-5A
    Publication number: 20190249223
    Abstract: The present disclosure relates, in general, to a fusion protein construct comprising RNase L and a split reporter system, and methods of using the reporter for detecting 2?-5? linked oligoadenylates (2-5A) and double stranded RNA in vivo.
    Type: Application
    Filed: February 15, 2019
    Publication date: August 15, 2019
    Inventors: Alexei Korennykh, Alisha Chitrakar, Jesse Donovan
  • METHOD OF MONITORING RNASE L ACTIVITY
    Publication number: 20190203259
    Abstract: The present disclosure relates, in general, to a method for generating chimeric DNA derived from RNase L cleavage products in a sample, and detection of such RNase L cleavage products for diagnosis and treatment of inflammation and infection in a subject.
    Type: Application
    Filed: May 5, 2017
    Publication date: July 4, 2019
    Inventors: Alexei Korennykh, Jesse Donovan