Patents by Inventor Jesse Erasmus

Jesse Erasmus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR DELIVERY OF RNA
    Publication number: 20260007769
    Abstract: The disclosure provides nanoemulsion compositions and methods of making and using thereof to deliver a bioactive agent such as a nucleic acid to a subject. The nanoemulsion composition comprises a hydrophobic core based on inorganic nanoparticles in a lipid nanoparticle that allows imaging as well as delivering nucleic acids. Methods of using these particles for treatment and vaccination are also provided.
    Type: Application
    Filed: September 10, 2025
    Publication date: January 8, 2026
    Inventors: Amit Khandhar, Steven Reed, Malcolm Duthie, Jesse Erasmus, Darrick Carter, Bryan J. Berube
  • Compositions and methods for delivery of RNA
    Patent number: 12433957
    Abstract: The disclosure provides nanoemulsion compositions and methods of making and using thereof to deliver a bioactive agent such as a nucleic acid to a subject. The nanoemulsion composition comprises a hydrophobic core based on inorganic nanoparticles in a lipid nanoparticle that allows imaging as well as delivering nucleic acids. Methods of using these particles for treatment and vaccination are also provided.
    Type: Grant
    Filed: September 23, 2024
    Date of Patent: October 7, 2025
    Assignee: HDT Bio Corp.
    Inventors: Amit Khandhar, Steven Reed, Malcolm Duthie, Jesse Erasmus, Darrick Carter, Bryan J. Berube
  • RNA VACCINES AGAINST INFECTIOUS DISEASES
    Publication number: 20250295751
    Abstract: The disclosure provides compositions, methods of treatment, and methods of making and using compositions to deliver a nucleic acid to a subject. Methods of using these compositions as a vaccine for treatment of an infectious disease are also provided.
    Type: Application
    Filed: May 29, 2025
    Publication date: September 25, 2025
    Inventors: Steven Gregory Reed, Darrick Albert Carter, Amit Praful Khandhar, Jacob Freeman Archer, Lars Peter Aksel Berglund, Jesse Erasmus, Bryan Berube, Malcolm S. Duthie
  • SARS-COV-2 RNA VACCINE COMPOSITIONS AND METHODS OF USE
    Publication number: 20250228930
    Abstract: The disclosure provides compositions, methods of treatment, and methods of making and using compositions to deliver a nucleic acid to a subject. Methods of using the compositions as a COVID-19 vaccine for the treatment of a coronavirus infection are also provided.
    Type: Application
    Filed: February 19, 2025
    Publication date: July 17, 2025
    Inventors: Steven Gregory Reed, Darrick Albert Carter, Amit Praful Khandhar, Jacob Freeman Archer, Lars Peter Aksel Berglund, Jesse Erasmus, Bryan Berube, Malcolm S. Duthie
  • RNA vaccines against infectious diseases
    Patent number: 12350329
    Abstract: The disclosure provides compositions, methods of treatment, and methods of making and using compositions to deliver a nucleic acid to a subject. Methods of using these compositions as a vaccine for treatment of an infectious disease are also provided.
    Type: Grant
    Filed: March 20, 2024
    Date of Patent: July 8, 2025
    Assignee: HDT Bio Corp.
    Inventors: Steven Gregory Reed, Darrick Albert Carter, Amit Praful Khandhar, Jacob Freeman Archer, Lars Peter Aksel Berglund, Jesse Erasmus, Bryan Berube, Malcolm S. Duthie
  • SARS-CoV-2 RNA vaccine compositions and methods of use
    Patent number: 12257299
    Abstract: The disclosure provides compositions, methods of treatment, and methods of making and using compositions to deliver a nucleic acid to a subject. Methods of using the compositions as a COVID-19 vaccine for the treatment of a coronavirus infection are also provided.
    Type: Grant
    Filed: March 21, 2024
    Date of Patent: March 25, 2025
    Assignee: HDT Bio Corp.
    Inventors: Steven Gregory Reed, Darrick Albert Carter, Amit Praful Khandhar, Jacob Freeman Archer, Lars Peter Aksel Berglund, Jesse Erasmus, Bryan Berube, Malcolm S. Duthie
  • COMPOSITIONS AND METHODS FOR DELIVERY OF RNA
    Publication number: 20250032639
    Abstract: The disclosure provides nanoemulsion compositions and methods of making and using thereof to deliver a bioactive agent such as a nucleic acid to a subject. The nanoemulsion composition comprises a hydrophobic core based on inorganic nanoparticles in a lipid nanoparticle that allows imaging as well as delivering nucleic acids. Methods of using these particles for treatment and vaccination are also provided.
    Type: Application
    Filed: September 23, 2024
    Publication date: January 30, 2025
    Inventors: Amit KHANDHAR, Steven REED, Malcolm DUTHIE, Jesse ERASMUS, Darrick CARTER, Bryan J. BERUBE
  • COMPOSITIONS AND METHODS FOR MULTIVALENT IMMUNE RESPONSES
    Publication number: 20240374714
    Abstract: The disclosure provides nanoparticle and nucleic acid compositions and methods of making and using the same to deliver multiple bioactive agents such as a nucleic acid encoding a viral antigen or a tumor antigen to a subject. Various nanoparticle carriers are described. Various nucleic acids encoding viral and tumor antigens are described. In some instances, the nanoparticle component may include a hydrophobic core having an inorganic particle, and optionally a membrane having a cationic lipid.
    Type: Application
    Filed: July 3, 2024
    Publication date: November 14, 2024
    Inventors: Malcolm S. Duthie, Jesse Erasmus, Lars Peter Aksel BERGLUND
  • Compositions and methods for delivery of RNA
    Patent number: 12133894
    Abstract: The disclosure provides nanoemulsion compositions and methods of making and using thereof to deliver a bioactive agent such as a nucleic acid to a subject. The nanoemulsion composition comprises a hydrophobic core based on inorganic nanoparticles in a lipid nanoparticle that allows imaging as well as delivering nucleic acids. Methods of using these particles for treatment and vaccination are also provided.
    Type: Grant
    Filed: December 20, 2023
    Date of Patent: November 5, 2024
    Assignee: HDT Bio Corp.
    Inventors: Amit Khandhar, Steven Reed, Malcolm Duthie, Jesse Erasmus, Darrick Carter, Bryan J. Berube
  • RNA VACCINES AGAINST INFECTIOUS DISEASES
    Publication number: 20240307521
    Abstract: The disclosure provides compositions, methods of treatment, and methods of making and using compositions to deliver a nucleic acid to a subject. Methods of using these compositions as a vaccine for treatment of an infectious disease are also provided.
    Type: Application
    Filed: March 20, 2024
    Publication date: September 19, 2024
    Inventors: Steven Gregory Reed, Darrick Albert Carter, Amit Praful Khandhar, Jacob Freeman Archer, Lars Peter Aksel Berglund, Jesse Erasmus, Bryan Berube, Malcolm S. Duthie
  • SARS-COV-2 RNA VACCINE COMPOSITIONS AND METHODS OF USE
    Publication number: 20240261393
    Abstract: The disclosure provides compositions, methods of treatment, and methods of making and using compositions to deliver a nucleic acid to a subject. Methods of using the compositions as a COVID-19 vaccine for the treatment of a coronavirus infection are also provided.
    Type: Application
    Filed: March 21, 2024
    Publication date: August 8, 2024
    Inventors: Steven Gregory Reed, Darrick Albert Carter, Amit Praful Khandhar, Jacob Freeman Archer, Lars Peter Aksel Berglund, Jesse Erasmus, Bryan Berube, Malcolm S. Duthie
  • COMPOSITIONS AND METHODS FOR DELIVERY OF RNA
    Publication number: 20240115728
    Abstract: The disclosure provides nanoemulsion compositions and methods of making and using thereof to deliver a bioactive agent such as a nucleic acid to a subject. The nanoemulsion composition comprises a hydrophobic core based on inorganic nanoparticles in a lipid nanoparticle that allows imaging as well as delivering nucleic acids. Methods of using these particles for treatment and vaccination are also provided.
    Type: Application
    Filed: December 20, 2023
    Publication date: April 11, 2024
    Inventors: Amit KHANDHAR, Steven REED, Malcolm DUTHIE, Jesse ERASMUS, Darrick CARTER, Bryan J. BERUBE
  • Compositions and methods for delivery of RNA
    Patent number: 11896677
    Abstract: The disclosure provides nanoemulsion compositions and methods of making and using thereof to deliver a bioactive agent such as a nucleic acid to a subject. The nanoemulsion composition comprises a hydrophobic core based on inorganic nanoparticles in a lipid nanoparticle that allows imaging as well as delivering nucleic acids. Methods of using these particles for treatment and vaccination are also provided.
    Type: Grant
    Filed: July 24, 2023
    Date of Patent: February 13, 2024
    Assignee: HDT Bio Corp.
    Inventors: Amit Khandhar, Steven Reed, Malcolm Duthie, Jesse Erasmus, Darrick Carter, Bryan J. Berube
  • COMPOSITIONS AND METHODS FOR DELIVERY OF RNA
    Publication number: 20230364260
    Abstract: The disclosure provides nanoemulsion compositions and methods of making and using thereof to deliver a bioactive agent such as a nucleic acid to a subject. The nanoemulsion composition comprises a hydrophobic core based on inorganic nanoparticles in a lipid nanoparticle that allows imaging as well as delivering nucleic acids. Methods of using these particles for treatment and vaccination are also provided.
    Type: Application
    Filed: July 24, 2023
    Publication date: November 16, 2023
    Inventors: Amit KHANDHAR, Steven REED, Malcolm DUTHIE, Jesse ERASMUS, Darrick CARTER, Bryan J. BERUBE
  • Nucleic acid-small diameter and liquid core nanoparticle complexed compositions
    Patent number: 11752218
    Abstract: The disclosure provides nanoemulsion compositions and methods of making and using thereof to deliver a bioactive agent such as a nucleic acid to a subject. The nanoemulsion composition comprises a hydrophobic core based on inorganic nanoparticles in a lipid nanoparticle that allows imaging as well as delivering nucleic acids. Methods of using these particles for treatment and vaccination are also provided.
    Type: Grant
    Filed: June 14, 2022
    Date of Patent: September 12, 2023
    Assignee: HDT Bio Corp.
    Inventors: Amit Khandhar, Steven Reed, Malcolm Duthie, Jesse Erasmus, Darrick Carter, Bryan J. Berube
  • Compositions and methods for delivery of RNA
    Patent number: 11679163
    Abstract: The disclosure provides nanoemulsion compositions and methods of making and using thereof to deliver a bioactive agent such as a nucleic acid to a subject. The nanoemulsion composition comprises a hydrophobic core based on inorganic nanoparticles in a lipid nanoparticle that allows imaging as well as delivering nucleic acids. Methods of using these particles for treatment and vaccination are also provided.
    Type: Grant
    Filed: November 22, 2022
    Date of Patent: June 20, 2023
    Assignee: HDT BIO CORP.
    Inventors: Amit Khandhar, Steven Reed, Malcolm Duthie, Jesse Erasmus, Darrick Carter, Bryan J. Berube
  • Compositions and methods for delivery of RNA
    Patent number: 11654200
    Abstract: The disclosure provides nanoemulsion compositions and methods of making and using thereof to deliver a bioactive agent such as a nucleic acid to a subject. The nanoemulsion composition comprises a hydrophobic core based on inorganic nanoparticles in a lipid nanoparticle that allows imaging as well as delivering nucleic acids. Methods of using these particles for treatment and vaccination are also provided.
    Type: Grant
    Filed: December 5, 2022
    Date of Patent: May 23, 2023
    Assignee: HDT Bio Corp.
    Inventors: Amit Khandhar, Steven Reed, Malcolm Duthie, Jesse Erasmus, Darrick Carter, Bryan J. Berube
  • Compositions and methods for delivery of RNA
    Patent number: 11648322
    Abstract: The disclosure provides nanoemulsion compositions and methods of making and using thereof to deliver a bioactive agent such as a nucleic acid to a subject. The nanoemulsion composition comprises a hydrophobic core based on inorganic nanoparticles in a lipid nanoparticle that allows imaging as well as delivering nucleic acids. Methods of using these particles for treatment and vaccination are also provided.
    Type: Grant
    Filed: November 22, 2022
    Date of Patent: May 16, 2023
    Assignee: HDT BIO CORP.
    Inventors: Amit Khandhar, Steven Reed, Malcolm Duthie, Jesse Erasmus, Darrick Carter, Bryan J. Berube
  • Compositions and methods for delivery of RNA
    Patent number: 11648321
    Abstract: The disclosure provides nanoemulsion compositions and methods of making and using thereof to deliver a bioactive agent such as a nucleic acid to a subject. The nanoemulsion composition comprises a hydrophobic core based on inorganic nanoparticles in a lipid nanoparticle that allows imaging as well as delivering nucleic acids. Methods of using these particles for treatment and vaccination are also provided.
    Type: Grant
    Filed: August 22, 2022
    Date of Patent: May 16, 2023
    Assignee: HDT BIO CORP.
    Inventors: Amit Khandhar, Steven Reed, Malcolm Duthie, Jesse Erasmus, Darrick Carter, Bryan J. Berube
  • COMPOSITIONS AND METHODS FOR DELIVERY OF RNA
    Publication number: 20230121003
    Abstract: The disclosure provides nanoemulsion compositions and methods of making and using thereof to deliver a bioactive agent such as a nucleic acid to a subject. The nanoemulsion composition comprises a hydrophobic core based on inorganic nanoparticles in a lipid nanoparticle that allows imaging as well as delivering nucleic acids. Methods of using these particles for treatment and vaccination are also provided.
    Type: Application
    Filed: November 22, 2022
    Publication date: April 20, 2023
    Inventors: Amit KHANDHAR, Steven REED, Malcolm DUTHIE, Jesse ERASMUS, Darrick CARTER, Bryan J. BERUBE