Patents by Inventor Jesse H. ERASMUS

Jesse H. ERASMUS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NANOSTRUCTURED LIPID CARRIERS AND STABLE EMULSIONS AND USES THEREOF
    Publication number: 20220054416
    Abstract: Provided herein are nanostructured lipid carrier compositions, and methods of making and using thereof. The compositions comprise a nanostructured lipid carrier (NLC), where the NLC comprises an oil core comprising a mixture of a liquid phase lipid and a solid phase lipid, a cationic lipid, a sorbitan ester, and a hydrophilic surfactant, and optionally a bioactive agent. The bioactive agent can be associated with the NLC. The compositions are capable of delivery of a biomolecule to a cell for the generation of an immune response, for example, for vaccine, therapeutic, or diagnostic uses. Compositions and methods related to making the compositions and using the compositions for stimulating an immune response are also provided.
    Type: Application
    Filed: September 9, 2021
    Publication date: February 24, 2022
    Inventors: Christopher B. FOX, Amit Praful KHANDHAR, Neal VAN HOEVEN, Jesse H. ERASMUS, Susan S. LIN
  • Nanostructured lipid carriers and stable emulsions and uses thereof
    Patent number: 11141377
    Abstract: Provided herein are nanostructured lipid carrier compositions, and methods of making and using thereof. The compositions comprise a nanostructured lipid carrier (NLC), where the NLC comprises an oil core comprising a mixture of a liquid phase lipid and a solid phase lipid, a cationic lipid, a sorbitan ester, and a hydrophilic surfactant, and optionally a bioactive agent. The bioactive agent can be associated with the NLC. The compositions are capable of delivery of a biomolecule to a cell for the generation of an immune response, for example, for vaccine, therapeutic, or diagnostic uses. Compositions and methods related to making the compositions and using the compositions for stimulating an immune response are also provided.
    Type: Grant
    Filed: June 15, 2018
    Date of Patent: October 12, 2021
    Assignee: Infectious Disease Research Institute
    Inventors: Christopher B. Fox, Amit Praful Khandhar, Neal Van Hoeven, Jesse H. Erasmus, Susan S. Lin
  • NANOSTRUCTURED LIPID CARRIERS AND STABLE EMULSIONS AND USES THEREOF
    Publication number: 20200230056
    Abstract: Provided herein are nanostructured lipid carrier compositions, and methods of making and using thereof. The compositions comprise a nanostructured lipid carrier (NLC), where the NLC comprises an oil core comprising a mixture of a liquid phase lipid and a solid phase lipid, a cationic lipid, a sorbitan ester, and a hydrophilic surfactant, and optionally a bioactive agent. The bioactive agent can be associated with the NLC. The compositions are capable of delivery of a biomolecule to a cell for the generation of an immune response, for example, for vaccine, therapeutic, or diagnostic uses. Compositions and methods related to making the compositions and using the compositions for stimulating an immune response are also provided.
    Type: Application
    Filed: June 15, 2018
    Publication date: July 23, 2020
    Inventors: Christopher B. FOX, Amit Praful KHANDHAR, Neal VAN HOEVEN, Jesse H. ERASMUS, Susan S. LIN