Patents by Inventor Jesse Hamilton

Jesse Hamilton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11927657
    Abstract: Methods and systems perform magnetic resonance fingerprinting (MRF) by obtaining scan data of a sample at a low-resolution over a k-space and obtaining other scan data at a high-resolution over the k-space. This scan data may be captured over the same regions, different regions, or where one scan data is captured over a sub-region of the other. The low-resolution and high-resolution scanning is repeated according to a scanning ratio between the first scan data and the second scan data to generate interleaved low-resolution and high-resolution scan data. From that interleaved low-resolution and high-resolution scan data, high-resolution tissue property maps of the sample are generated.
    Type: Grant
    Filed: April 13, 2022
    Date of Patent: March 12, 2024
    Assignee: REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Kathleen Ropella Panagis, Nicole Seiberlich, Jesse Hamilton
  • Publication number: 20230333189
    Abstract: Methods and systems perform magnetic resonance fingerprinting (MRF) by obtaining scan data of a sample at a low-resolution over a k-space and obtaining other scan data at a high-resolution over the k-space. This scan data may be captured over the same regions, different regions, or where one scan data is captured over a sub-region of the other. The low-resolution and high-resolution scanning is repeated according to a scanning ratio between the first scan data and the second scan data to generate interleaved low-resolution and high-resolution scan data. From that interleaved low-resolution and high-resolution scan data, high-resolution tissue property maps of the sample are generated.
    Type: Application
    Filed: April 13, 2022
    Publication date: October 19, 2023
    Inventors: Kathleen Ropella Panagis, Nicole Seiberlich, Jesse Hamilton
  • Patent number: 11719778
    Abstract: Methods and systems generate synthetic late gadolinium enhancement (LGE) magnetic resonance images using a magnetic resonance fingerprinting (MRF) acquisition. From a single acquisition, MRF image data is obtained, including co-registered T1 and T2 tissue property maps. Different tissue regions of interest are identified, such as viable myocardium, scar, and blood and T1 and T2 values for each are determined. Based on these, different sets of pulse sequence parameters are determined, e.g., using different synthetic image contrast models receiving the MRF image data. Synthetic LGE images at different contrasts are generated as a result, including a synthetic bright-blood LGE image, a synthetic dark-blood/gray-blood LGE image, and a synthetic optimized imaged.
    Type: Grant
    Filed: January 31, 2022
    Date of Patent: August 8, 2023
    Assignees: REGENTS OF THE UNIVERSITY OF MICHIGAN, CASE WESTERN RESERVE UNIVERSITY, UNIVERSITY HOSPITALS CLEVELAND MEDICAL CENTER
    Inventors: Jesse Hamilton, Imran Rashid, Nicole Seiberlich, Sanjay Rajagopalan
  • Publication number: 20230245354
    Abstract: A computing system for self-training of a magnetic resonance imaging (MRI) tissue property artificial neural network (ANN) includes a processor and an ANN training application including instructions that, when executed by the one or more processors, are configured to cause the processor to generate tissue property maps; generate MRI fingerprint images; generate reconstructed MRI k-space data; and compare the reconstructed MRI k-space data to acquired MRI k-space data. A computer-implemented method includes generating tissue property maps; generating MRI fingerprint images; generating reconstructed MRI k-space data; and comparing the reconstructed MRI k-space data to acquired MRI k-space data. A non-transitory computer-readable storage medium storing executable instructions that, when executed by a processor, cause a computer to generate tissue property maps; generate MRI fingerprint images; generate reconstructed MRI k-space data; and compare the reconstructed MRI k-space data to acquired MRI k-space data.
    Type: Application
    Filed: February 1, 2022
    Publication date: August 3, 2023
    Inventor: Jesse Hamilton
  • Publication number: 20230243909
    Abstract: Methods and systems generate synthetic late gadolinium enhancement (LGE) magnetic resonance images using a magnetic resonance fingerprinting (MRF) acquisition. From a single acquisition, MRF image data is obtained, including co-registered T1 and T2 tissue property maps. Different tissue regions of interest are identified, such as viable myocardium, scar, and blood and T1 and T2 values for each are determined. Based on these, different sets of pulse sequence parameters are determined, e.g., using different synthetic image contrast models receiving the MRF image data. Synthetic LGE images at different contrasts are generated as a result, including a synthetic bright-blood LGE image, a synthetic dark-blood/gray-blood LGE image, and a synthetic optimized imaged.
    Type: Application
    Filed: January 31, 2022
    Publication date: August 3, 2023
    Inventors: Jesse Hamilton, Imran Rashid, Nicole Seiberlich, Sanjay Rajagopalan
  • Patent number: 11313931
    Abstract: A method for quantifying T1, T2 and resonance frequency simultaneously using magnetic resonance fingerprinting (MRF) includes accessing an MRF dictionary using a magnetic resonance imaging (MRI) system. The MRF dictionary is generated by simulating signal evolutions that include associated off-resonance effects for each signal evolution. The method further includes acquiring MRF data from a region of interest in a subject using the MRI system and a MRF pulse sequence having a plurality of radio frequency (RF) excitations and a readout associated with each RF excitation. Each readout includes a plurality of segments and each segment is used to generate a time frame. The method also include comparing the MRF data to the MRF dictionary to identify a plurality of parameters including T1, T2 and resonance frequency for the MRF data and generating a report indicating the at least one of the plurality of parameters of the MRF data.
    Type: Grant
    Filed: May 17, 2019
    Date of Patent: April 26, 2022
    Assignee: Case Western Reserve University
    Inventors: Yuchi Liu, Jesse Hamilton, Nicole Seiberlich, Mark A. Griswold
  • Publication number: 20220080235
    Abstract: The presently claimed invention relates to a fire barrier, a method for installing the same, an expansion joint system and a fire barrier assembly.
    Type: Application
    Filed: November 23, 2021
    Publication date: March 17, 2022
    Inventors: John SOBOL, Gary MOORE, Neil Jesse HAMILTON, Paul PUMM, Greg ROSS
  • Patent number: 11180914
    Abstract: The presently claimed invention relates to a fire barrier, a method for installing the same, an expansion joint system and a fire barrier assembly.
    Type: Grant
    Filed: December 10, 2019
    Date of Patent: November 23, 2021
    Assignee: Watson Bowman Acme Corporation
    Inventors: John Sobol, Gary Moore, Neil Jesse Hamilton
  • Patent number: 11125847
    Abstract: A method for magnetic resonance fingerprinting with out-of-view artifact suppression includes acquiring MRF data from a region of interest in a subject. The MRF data is acquired using a non-Cartesian, variable density sampling trajectory. The MRF data includes data from within a desired field-of-view and data from outside the desired field-of-view. The method also includes generating a set of coil images based on the MRF data with a field-of-view larger than the desired field-of-view, determining a noise covariance based on the MRF data from outside the desired field-of-view, generating a coil combined image using an adaptive coil combination determined based on the noise covariance, applying the adaptive coil combination to the MRF data to grid each frame of the MRF data and generate MRF data with out-of-view artifact suppression. The method also includes identifying at least one property of the MRF data and generating a report.
    Type: Grant
    Filed: April 24, 2020
    Date of Patent: September 21, 2021
    Assignee: Case Western Reserve University
    Inventors: Brendan Eck, Jesse Hamilton, Nicole Seiberlich, Mark Griswold
  • Publication number: 20200341102
    Abstract: A method for magnetic resonance fingerprinting with out-of-view artifact suppression includes acquiring MRF data from a region of interest in a subject. The MRF data is acquired using a non-Cartesian, variable density sampling trajectory. The MRF data includes data from within a desired field-of-view and data from outside the desired field-of-view. The method also includes generating a set of coil images based on the MRF data with a field-of-view larger than the desired field-of-view, determining a noise covariance based on the MRF data from outside the desired field-of-view, generating a coil combined image using an adaptive coil combination determined based on the noise covariance, applying the adaptive coil combination to the MRF data to grid each frame of the MRF data and generate MRF data with out-of-view artifact suppression. The method also includes identifying at least one property of the MRF data and generating a report.
    Type: Application
    Filed: April 24, 2020
    Publication date: October 29, 2020
    Inventors: Brendan Eck, Jesse Hamilton, Nicole Seiberlich, Mark Griswold
  • Publication number: 20190353731
    Abstract: A method for quantifying T1, T2 and resonance frequency simultaneously using magnetic resonance fingerprinting (MRF) includes accessing an MRF dictionary using a magnetic resonance imaging (MRI) system. The MRF dictionary is generated by simulating signal evolutions that include associated off-resonance effects for each signal evolution. The method further includes acquiring MRF data from a region of interest in a subject using the MRI system and a MRF pulse sequence having a plurality of radio frequency (RF) excitations and a readout associated with each RF excitation. Each readout includes a plurality of segments and each segment is used to generate a time frame. The method also include comparing the MRF data to the MRF dictionary to identify a plurality of parameters including T1, T2 and resonance frequency for the MRF data and generating a report indicating the at least one of the plurality of parameters of the MRF data.
    Type: Application
    Filed: May 17, 2019
    Publication date: November 21, 2019
    Inventors: Yuchi Liu, Jesse Hamilton, Nicole Seiberlich, Mark A. Griswold
  • Patent number: 10145917
    Abstract: Example embodiments associated with characterizing a sample using NMR fingerprinting are described. One example NMR apparatus includes an NMR logic that repetitively and variably samples a (k, t, E) space associated with an object to acquire a set of NMR signals that are associated with different points in the (k, t, E) space. Sampling is performed with t and/or E varying in a non-constant way. The NMR apparatus may also include a signal logic that produces an NMR signal evolution from the NMR signals and a characterization logic that characterizes a tissue in the object as a result of comparing acquired signals to reference signals. Example embodiments facilitate analyzing voxels having multiple compartments that may experience magnetic exchange. The compartments may be, for example, an intracellular volume and an extracellular volume in a tissue that experiences magnetic exchange due to the movement of water between the volumes.
    Type: Grant
    Filed: November 4, 2015
    Date of Patent: December 4, 2018
    Assignee: Case Western Reserve University
    Inventors: Nicole Seiberlich, Jesse Hamilton, Mark Griswold
  • Publication number: 20160282434
    Abstract: Example embodiments associated with characterizing a sample using NMR fingerprinting are described. One example NMR apparatus includes an NMR logic that repetitively and variably samples a (k, t, E) space associated with an object to acquire a set of NMR signals that are associated with different points in the (k, t, E) space. Sampling is performed with t and/or E varying in a non-constant way. The NMR apparatus may also include a signal logic that produces an NMR signal evolution from the NMR signals and a characterization logic that characterizes a tissue in the object as a result of comparing acquired signals to reference signals. Example embodiments facilitate analyzing voxels having multiple compartments that may experience magnetic exchange. The compartments may be, for example, an intracellular volume and an extracellular volume in a tissue that experiences magnetic exchange due to the movement of water between the volumes.
    Type: Application
    Filed: November 4, 2015
    Publication date: September 29, 2016
    Inventors: Nicole Seiberlich, Jesse Hamilton, Mark Griswold
  • Patent number: 5112223
    Abstract: The present invention relates to kiln car refractory furniture. In combination, (a) a kiln car having chassis that carries a platform; (b) a curb of a row of a plurality of hollow load-bearing refractory modules aligned along the periphery of the platform of the kiln car; and (c) an insulating amount of refractory insulation dispersed between the modules and laying over the platform of the kiln car. Each load-bearing hollow refractory module further comprises: (i) a hollow body formed of a refractory material having spaced walls and a top wall defining a hollow insulating space; (ii) at least one socket means for supporting a refractory post where the post in turn supports a load of refractory ware; (iii) a securing means for supporting the socket means spaced apart from the platform of the kiln car; and (iv) surfaces on the body adapted to interlock with surfaces on another abutting module.
    Type: Grant
    Filed: March 4, 1991
    Date of Patent: May 12, 1992
    Assignee: Dal-Tile Corporation
    Inventors: Warren R. Walle, Jack B. Ross, Jesse A. Hamilton, Delfin C. Martinez