Abstract: Devices and methods are provided for trans-esophageal aortic flow control. The device comprises a controller, an esophageal tube extending from the controller, an anchor device at a distal end of the esophageal tube and configured to anchor the distal end of the device inside a patient's stomach, and an actuator positioned proximally to the anchoring device by a sufficient distance so that the actuator will be proximal to the intersection of the patient's esophagus with their diaphragm when the anchoring device is positioned inside of the patient's stomach. In this position, the anchoring device is aligned with the location at which the patient's esophagus and aorta cross that is above (or proximal to) the intersection with the patient's diaphragm, with the patient's aorta then positioned between the spine and the esophagus.