Patents by Inventor Jesse Klein
Jesse Klein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250108046Abstract: A pharmaceutical composition in the form of droplets for oral administration is disclosed. The pharmaceutical composition is an aqueous solution comprising sodium chloride in an amount of 0.6% to 3% by weight per volume, at least one active ingredient selected from naloxone, yohimbine, albuterol, epinephrine, buprenorphine, and exosomes in an amount of 0.01% to 25% by weight per volume, and having a pH from 3 to 7.5. The composition is converted into droplets with diameters of 0.5 to 5 microns using an atomizer with a vibrating mesh membrane undergoing piezoelectric vibration at a frequency of 25 to 400 kilohertz. The process involves providing the composition in a capsule, inserting the capsule into the atomizer, and activating the atomizer to produce droplets. This system provides precise, efficient, and patient-friendly oral delivery of medications.Type: ApplicationFiled: December 11, 2024Publication date: April 3, 2025Inventors: Pradeep Albert, Christine Nichols, David J. Condron, Brian Artze, Fadi Saba, Jesse Klein, Vijay Vad, Stephen Naeger
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Patent number: 12194037Abstract: A pharmaceutical composition and method for treating opioid overdose, opioid dependency, and xylazine exposure is disclosed, utilizing an aqueous solution of sodium chloride. This solution contains active ingredients such as naloxone and yohimbine in specific concentrations, with naloxone targeting opioid overdose and yohimbine aimed at counteracting xylazine effects. In various embodiments, additional components like tolazoline and different buffers can be included. The disclosure introduces a unique delivery system that features a capsule with a vibrating mesh atomizer for efficient administration. Specifically, for yohimbine, a dual-reservoir capsule design facilitates controlled mixing with diluents or buffers. The administration of this pharmaceutical composition can be achieved through multiple methods, including intramuscular, intravenous, and atomized routes. The atomizing device incorporates a removable cap and a resilient air bladder, ensuring effective drug delivery.Type: GrantFiled: December 5, 2023Date of Patent: January 14, 2025Inventors: Pradeep Albert, Christine Nichols, David J. Condron, Brian Artze, Fadi Saba, Jesse Klein, Vijay Vad, Stephen Naeger
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Patent number: 12171938Abstract: Apparatus, methods, and systems for delivery and administration of pharmaceutical, therapeutic and cosmetic substances to users. The method includes providing a removable capsule having an atomizer, inserting the removable capsule in a channel of a base unit of a device. The channel is in fluid communication with a mixing chamber of the base unit, and the base unit defines openings on the base unit configured to receive a portion of a conduit and a removable air mover unit. Further, the method includes dispensing, using the atomizer, the at least one medication from the removable capsule to the mixing chamber of the base unit, and using the removable air mover unit, causing air and the at least one medication within the mixing chamber to be conveyed from the mixing chamber to the conduit such that air and the at least one medication dispensed from the removable capsule exits the conduit.Type: GrantFiled: April 9, 2024Date of Patent: December 24, 2024Inventors: Pradeep Albert, Christine Nichols, David J. Condron, Brian Artze, Fadi Saba, Jesse Klein, Vijay Vad
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Patent number: 12156966Abstract: Methods and systems for delivering formulations to users using modular device having atomizer and wick assembly are disclosed. A formulation delivery system that includes a mouthpiece with a first attaching structure at one end and a removable cartridge with a second attaching structure that connects to the mouthpiece. The removable cartridge houses an atomizer at its first end and features a wick assembly with a removable cap and a wick made from an absorbent material. The wick, which transports fluid to the atomizer, is connected at one end to the removable cap and at the other end abuts the atomizer. The system also includes a channel within the removable cartridge; this channel extends to the cartridge's first end and houses the wick, while the removable cap is located outside the channel. Additionally, the system incorporates electronics that maintain a removable electrical connection with the cartridge.Type: GrantFiled: May 3, 2024Date of Patent: December 3, 2024Inventors: Pradeep Albert, Christine Nichols, David J. Condron, Brian Artze, Fadi Saba, Jesse Klein, Vijay Vad, Shawn Best
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Publication number: 20240383667Abstract: Provided herein are systems and methods for a Pill Packet Dispenser with a clamshell container.Type: ApplicationFiled: April 8, 2024Publication date: November 21, 2024Inventors: Andrew Brandeis, Noah Austin, Pepin Sebastian Gelardi, Jesse Klein, Henry Ripley
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Publication number: 20240290162Abstract: A dispensing unit for personal care products and personal protective equipment includes one or more dispensing assemblies contained within a single housing. The dispensing unit may contain dispensing assemblies that independently dispense two different types of products. Each dispensing assembly includes an actuator that mechanically injects a time delay between dispensings. Products are bundled together with support structures that are removed when the bundles are placed into a dispensing assembly.Type: ApplicationFiled: May 7, 2024Publication date: August 29, 2024Inventors: Claire Coder, Anne Weigand, Pepin Gelardi, Emma Pearl Wilmer-Shiles, Gordon Thomas, Mark Dalhart, Jesse Klein
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Publication number: 20240277949Abstract: Methods and systems for delivering formulations to users using modular device having atomizer and wick assembly are disclosed. A formulation delivery system that includes a mouthpiece with a first attaching structure at one end and a removable cartridge with a second attaching structure that connects to the mouthpiece. The removable cartridge houses an atomizer at its first end and features a wick assembly with a removable cap and a wick made from an absorbent material. The wick, which transports fluid to the atomizer, is connected at one end to the removable cap and at the other end abuts the atomizer. The system also includes a channel within the removable cartridge; this channel extends to the cartridge's first end and houses the wick, while the removable cap is located outside the channel. Additionally, the system incorporates electronics that maintain a removable electrical connection with the cartridge.Type: ApplicationFiled: May 3, 2024Publication date: August 22, 2024Inventors: Pradeep Albert, Christine Nichols, David J. Condron, Brian Artze, Fadi Saba, Jesse Klein, Vijay Vad, Shawn Best
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Publication number: 20240226092Abstract: A pharmaceutical composition and method for treating opioid overdose, opioid dependency, and xylazine exposure is disclosed, utilizing an aqueous solution of sodium chloride. This solution contains active ingredients such as naloxone and yohimbine in specific concentrations, with naloxone targeting opioid overdose and yohimbine aimed at counteracting Xylazine effects. In various embodiments, additional components like tolazoline and different buffers can be included. The disclosure introduces a unique delivery system that features a capsule with a vibrating mesh atomizer for efficient administration. Specifically, for yohimbine, a dual-reservoir capsule design facilitates controlled mixing with diluents or buffers. The administration of this pharmaceutical composition can be achieved through multiple methods, including intramuscular, intravenous, and atomized routes. The atomizing device incorporates a removable cap and a resilient air bladder, ensuring effective drug delivery.Type: ApplicationFiled: December 5, 2023Publication date: July 11, 2024Inventors: Pradeep Albert, Christine Nichols, David J. Condron, Brian Artze, Fadi Saba, Jesse Klein, Vijay Vad, Stephen Naeger
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Patent number: 11944742Abstract: A method for veterinary administration of medication to an animal, particularly a horse, is disclosed. The method involves inserting a capsule containing the medication, which is a liquid formulation, into a device connected to a tubular chamber. An atomizer is activated to atomize the medication, producing atomized medication. Before administration, a force is applied to a mask placed over the animal's muzzle, connected to the chamber. The atomized medication is then delivered to the animal. The liquid formulation, in some instances, comprises cells, cellular byproducts, or cell-derived products such as stem cells or products from human mesenchymal stem cells. This formulation may lack preservatives and may encompass peptides, proteins, growth factors, cytokines, exosomes, and extracellular vesicles. The delivery mechanism may involve deflating an air bladder to convey the atomized medication.Type: GrantFiled: September 26, 2023Date of Patent: April 2, 2024Inventors: Pradeep Albert, Christine Nichols, David J. Condron, Brian Artze, Fadi Saba, Jesse Klein, Vijay Vad
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Patent number: 11925748Abstract: The invention pertains to a capsule system for use with a medical device designed to administer atomized medication to patients. The system features a chamber containing the medication and an atomizer at a lower end for efficient drug delivery. Notably, the system incorporates a fluid sensor and electrical contacts to ensure proper operation and medication delivery. The capsule's design includes a housing with an asymmetrical transverse cross-sectional shape for unique fitting, and a tapered wall to direct medication towards the atomizer. The capsule may also connect to an external container or include a stopper for refilling medication. A specific embodiment features two chambers with a rupturing element to facilitate medication transfer. Another embodiment includes a removable container, like a vial, within the first chamber. This novel system provides improvements in accuracy, versatility, and user-friendliness, overcoming limitations in prior art.Type: GrantFiled: August 15, 2023Date of Patent: March 12, 2024Inventors: Pradeep Albert, Christine Nichols, David J. Condron, Brian Artze, Fadi Saba, Jesse Klein, Vijay Vad
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Patent number: 11850356Abstract: A system for administering at least one medication to a patient is disclosed. The system includes a resilient air bladder in fluid communication with a tubular chamber of a base unit, a capsule in fluid communication with the tubular chamber configured for carrying the at least one medication, and an atomizer disposed at least proximate to the capsule and in fluid communication with the tubular chamber. An air inlet and a first one-way valve is in fluid communication with the resilient air bladder configured to allow fresh air to enter the resilient air bladder. An air outlet and a second one-way value is in fluid communication the resilient air bladder and the tubular chamber. Fresh air and the medication atomized by the atomizer mix together within the tubular chamber.Type: GrantFiled: June 8, 2023Date of Patent: December 26, 2023Inventors: Pradeep Albert, Christine Nichols, David J. Condron, Brian Artze, Fadi Saba, Jesse Klein, Vijay Vad
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Patent number: 11844900Abstract: A method is disclosed for administering medication to conscious or unconscious patients using a device with a tubular chamber. The method involves the use of a device with a tubular chamber, wherein a liquid medication is contained within a capsule. The medication is atomized by activating an atomizer, thereby generating an atomized medication consisting of particles with a maximum diameter of four microns. The atomized medication is then dispensed into the tubular chamber. Using the device, the atomized medication is administered to the patient. In cases of unconsciousness, a resilient air bladder connected to the chamber is partially deflated, allowing air transfer into the chamber. This facilitates the administration of the atomized medication. This method enables effective medication delivery in various emergency scenarios, ensuring appropriate treatment even for unresponsive patients by providing a method of using a device with modular components.Type: GrantFiled: July 20, 2023Date of Patent: December 19, 2023Inventors: Pradeep Albert, Christine Nichols, David J. Condron, Brian Artze, Fadi Saba, Jesse Klein, Vijay Vad
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Publication number: 20230126935Abstract: The present disclosure relates to a foldable vehicle and to several exemplary components thereof, which may comprise a hinge cassette and a rear wheel brake assembly among other components. In some examples, the vehicle has a folded configuration and an unfolded configuration, where in the folded configuration, the at least one rear wheel nests within the at least one opening.Type: ApplicationFiled: October 20, 2022Publication date: April 27, 2023Inventors: Theodore Ullrich, Jackson Zhao, Joe Gonzalez, Jesse Klein, David Azar Serur, Pepin Gelardi
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Publication number: 20230120468Abstract: A dispensing unit for personal care products and personal protective equipment includes one or more dispensing assemblies contained within a single housing. The dispensing unit may contain dispensing assemblies that independently dispense two different types of products. Each dispensing assembly includes an actuator that mechanically injects a time delay between dispensings. Products are bundled together with support structures that are removed when the bundles are placed into a dispensing assembly.Type: ApplicationFiled: December 19, 2022Publication date: April 20, 2023Inventors: Claire Coder, Anne Weigand, Pepin Gelardi, Emma Pearl Wilmer-Shiles, Gordon Thomas, Mark Dalhart, Jesse Klein
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Patent number: 11532197Abstract: A dispensing unit for personal care products and personal protective equipment includes one or more dispensing assemblies contained within a single housing. The dispensing unit may contain dispensing assemblies that independently dispense two different types of products. Each dispensing assembly includes an actuator that mechanically injects a time delay between dispensings. Products are bundled together with support structures that are removed when the bundles are placed into a dispensing assembly.Type: GrantFiled: August 8, 2020Date of Patent: December 20, 2022Assignee: Aunt Flow Corp.Inventors: Claire Coder, Anne Weigand, Pepin Gelardi, Emma Pearl Wilmer-Shiles, Gordon Thomas, Mark Dalhart, Jesse Klein
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Publication number: 20210043023Abstract: A dispensing unit for personal care products and personal protective equipment includes one or more dispensing assemblies contained within a single housing. The dispensing unit may contain dispensing assemblies that independently dispense two different types of products. Each dispensing assembly includes an actuator that mechanically injects a time delay between dispensings. Products are bundled together with support structures that are removed when the bundles are placed into a dispensing assembly.Type: ApplicationFiled: August 8, 2020Publication date: February 11, 2021Inventors: Claire Coder, Anne Weigand, Pepin Gelardi, Emma Pearl Wilmer-Shiles, Gordon Thomas, Mark Dalhart, Jesse Klein
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Publication number: 20200408422Abstract: Embodiments are disclosed of a radiator temperature control apparatus for controlling the heat output of a radiator. The radiator temperature control apparatus may include an airtight enclosure around the air outlet of the radiator air vent, an adjustable opening in the airtight enclosure controlled by an actuator, and a controller connected to the actuator. In operation, the controller can be configured to open the adjustable opening in the airtight enclosure allowing air in the radiator to be expelled through the adjustable opening, thereby allowing steam to enter the radiator, and heat the room. The controller can be configured to close the adjustable opening, stopping air from being expelled from the radiator, thereby stopping additional steam from entering the radiator.Type: ApplicationFiled: September 14, 2020Publication date: December 31, 2020Inventors: Pepin Gelardi, Joseph Gonzalez, Jingwen Zhu, Jackson Zhao, Jesse Klein, Andrew Staniforth
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Publication number: 20070285956Abstract: A method and apparatus for controlling a power supply. The system includes a power supply and a controller for outputting a command signal to regulate the operation of the power supply. The controller determines the command signal based on at least one error signal which is selected from a plurality of error signals based on a selection criterion.Type: ApplicationFiled: April 4, 2007Publication date: December 13, 2007Applicant: ENI Technology, Inc.Inventors: Sean Harnett, Mark Tracy, Jesse Klein
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Publication number: 20050041446Abstract: A method and apparatus for controlling a power supply. The system includes a power supply and a controller for outputting a command signal to regulate the operation of the power supply. The controller determines the command signal based on at least one error signal which is selected from a plurality of error signals based on a selection criterion.Type: ApplicationFiled: August 18, 2004Publication date: February 24, 2005Applicant: ENI Technology, Inc.Inventors: Sean Harnett, Mark Tracy, Jesse Klein
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Publication number: 20050040794Abstract: A fault handling algorithm processes a plurality of fault status signals from a sputtering system in a period of time to generate at least one command signal for affecting the operation of a power generator.Type: ApplicationFiled: August 18, 2003Publication date: February 24, 2005Inventors: Mark Tracy, Jesse Klein