Abstract: Suprachoroidal implantable devices formed of a compliant material have an external surface and an opposing internal surface with varying porosity extending through the compliant material or presenting external and internal surfaces with differing porosities. The compliant material surfaces either facilitate or inhibit tissue ingrowth into the material. The device and methods of using the device reduce pressure in the eye by directing fluid through the compliant material.

Abstract: A drainage device for draining a biological fluid from an eye to a tissue external to the eye is implantable at least in part within a tissue of the eye. The drainage device includes a body portion which includes a membrane having a first surface with a first porosity and a second surface with a second porosity greater than the first porosity, and a plate having a porosity less than the first porosity. The membrane is more flexible than the plate and has a first thickness from 25 ?m to 125 ?m. The plate has a second thickness from 0.8 mm to 2.0 mm. The membrane and plate define a reservoir. A conduit fluidly coupled with the reservoir and insertable into the eye facilitates drainage of fluid into the conduit. The second surface of the membrane includes ingrowth surface region(s) for facilitating ingrowth of tissue external to the eye.

Abstract: A drainage device for draining a biological fluid from an eye to a tissue external to the eye is disclosed. The drainage device is implantable at least in part within a tissue of the eye. The drainage device includes: an open collapsible body portion having a first surface with a first porosity and a second surface with a second porosity that is greater than the first porosity, the second surface opposing the first surface; and a conduit having a first end fluidly coupled with the first surface and a second end insertable into the eye to facilitate a drainage of the biological fluid into the conduit. The second surface with the second porosity includes at least one ingrowth surface region for facilitating ingrowth of tissue external to the eye.

Abstract: A glaucoma shunt device is provided for draining a biological fluid from an eye. The glaucoma shunt device includes a primary tube, a secondary tube, and a shunt body. The primary tube has a primary proximal end, a primary distal end, and a primary conduit extending therebetween. The secondary tube has a secondary proximal end, a secondary distal end, and a secondary conduit extending therebetween. The secondary tube is at least partially inserted through the primary conduit via the primary distal end. The secondary tube defines a flow resistance of the primary and secondary tubes. The shunt body has a reservoir therein and is integrated with the primary tube near the primary distal end such that the primary and secondary conduits are fluidly coupled with the reservoir.

Abstract: Drainage device for draining a biological fluid from an eye to a tissue external to the eye, as well as methods of forming the drainage device and treating glaucoma using the drainage device, are disclosed. The drainage device is implantable at least in part within a tissue of the eye and includes a collapsible body portion defining a reservoir, and a conduit having a first end fluidly coupled with the reservoir and a second end insertable into the eye to facilitate a drainage of the biological fluid into the conduit. When collapsed, the body portion includes a deformation from a first planar state to a second nonplanar state, where the second nonplanar state may be a folded, deformed, bent, or crumpled state.