Abstract: A system is disclosed for recommending a thermal pad set for use in providing a targeted temperature management (TTM) therapy to a patient, where the system includes a computer implemented method. The computer implemented method includes receiving a request for a thermal pad set recommendation from a clinician device, receiving a patient's identification from the clinician device, retrieving one or more patient parameter values from an electronic medical record for the patient, determining a pad set recommendation according to the patient parameter values in combination with a pad set correlation table, and displaying the pad set recommendation on the clinician device. Also disclosed herein is a system including a non-transitory computer-readable medium with instructions encoded thereon and one or more processors configured to, when executing the instructions, perform operations in accordance with processes of the computer implemented method.

Abstract: A microprocessor executable method and system for determining the semantic relatedness and meaning between at least two natural language sources is described in a prescribed context. Portions of natural languages are vectorized and mathematically processed to express relatedness as a calculated metric. The metric is associable to the natural language sources to graphically present the level of relatedness between at least two natural language sources. The metric may be re-determined with algorithms designed to compare the natural language sources with a knowledge data bank so the calculated metric can be ascertained with a higher level of certainty.

Abstract: Disclosed herein are systems and methods for providing targeted temperature management (TTM) therapy to a patient. For example, TTM systems include a connection system for coupling a fluid deliver line to a thermal contact pad. The connection system is configured to provide indication to the user that the fluid deliver line is completely connected to thermal contact pad. In addition, the connection system also includes a controller for activating a connection lock and for sharing signals with a TTM system module. The fluid deliver line includes a pair of conduits arranged concentrically and the thermal pad includes a TTM fluid filter disposed within a fluid containing layer.

Abstract: A crime center system generating a graphical user interface (GUI), which may be map-based, that facilitates efficient following of a moving object across cameras covering a geographic area. The system processes information on a network of cameras to determine the locations the cameras and their orientations. An object-tracking interface is generated by the system that includes an active camera view window presenting video from a camera capturing video of the geographic area that includes the tracked object. The system determines a set of the cameras, based on known locations and orientations, capturing images about the geographic space captured by the active camera. The system generates a “halo” of camera icons in the object-tracking interface around the periphery of the active camera view window, which provides a 360-degree view of available cameras about the active camera's location allowing a user to select a next active camera to efficiently track an object.

Abstract: A microprocessor executable method and system for determining the semantic relatedness and meaning between at least two natural language sources is described in a prescribed context. Portions of natural languages are vectorized and mathematically processed to express relatedness as a calculated metric. The metric is associable to the natural language sources to graphically present the level of relatedness between at least two natural language sources. The metric may be re-determined with algorithms designed to compare the natural language sources with a knowledge data bank so the calculated metric can be ascertained with a higher level of certainty.

Abstract: Systems and methods for synchronous content viewing are provided. In embodiments, a method includes providing an interface to a user of a remote user device; receiving a user selection of one or more contacts of the user as invitees to a synchronized session; providing content synchronously to the remote user device of the user and other remote user devices of the respective one or more contacts of the user based on receiving an acceptance from the one or more contacts of the user, wherein the user and the one or more contacts of the user view the content synchronously during the synchronized session; and providing functions of an application to the participants synchronously, wherein the functions enable the participants to interact with the content in real-time during the synchronized session, and wherein all participants view interactions with the content simultaneously.

Abstract: An electrosurgical system includes an electrosurgical unit electrically coupled to a surgical retractor. The electrosurgical unit includes an RF output and an RF return. The surgical retractor includes a return pad electrically coupled to the RF return of the electrosurgical unit. The electrosurgical unit includes an RF output configured to be coupled to an electrosurgical device, such as an electrosurgical device configured in a monopolar mode. A controller is configured to determine an impedance in tissue at a surgical area electrically disposed between the RF output and the and the RF return. The surgical retractor includes a handle and a blade configured to interface with tissue. The blade includes a return electrode.

Abstract: An electrosurgical system includes an electrosurgical unit electrically coupled to a surgical retractor. The electrosurgical unit includes an RF output and an RF return. The surgical retractor includes a return pad electrically coupled to the RF return of the electrosurgical unit. The electrosurgical unit includes an RF output configured to be coupled to an electrosurgical device, such as an electrosurgical device configured in a monopolar mode. A controller is configured to determine an impedance in tissue at a surgical area electrically disposed between the RF output and the and the RF return. The surgical retractor includes a handle and a blade configured to interface with tissue. The blade includes a return electrode.

Abstract: Disclosed herein is a system, apparatus and method directed to patient temperature control. The system can include a control module configured to provide fluid that is heated or cooled, a heating and cooling system configured to couple with the control module and receive the fluid, and a temperature sensor coupled to the control module, the temperature sensor configured to measure a body temperature of a patient and provide signals to the control module that indicate the body temperature. The system can include a neurostimulation device coupled to the control module to provide neurostimulation to the patient. The control module can include logic, stored on non-transitory, computer-readable medium that, when executed by one or more processors, causes performance of operations including generation and transmission of first instructions to the neurostimulation device causing initiation of a first neurostimulation procedure.

Abstract: In one or more arrangements, a tag system for monitoring of livestock is presented. The system includes at least one tag and a control system communicatively connected to the tag. In one or more arrangements, the tag includes a housing and a connector configured to operably connect with the housing to facilitate attachment of the tag to an animal. The tag also includes a set of sensors. In one or more arrangements, the set of sensors includes a first temperature sensor configured to monitor a temperature of the animal (animal reference temperature), a second temperature sensor configured to monitor an ambient temperature (ambient reference temperature) of the environment where the animal is located, a gyroscopic sensor, and/or an accelerometer sensor. In one or more arrangements, the tag includes an electronic circuit positioned within the housing and configured to communicate data from the set of sensors to the control system.

Abstract: A heating mat system is presented for use with livestock. The heating mat system includes a heating layer positioned between an upper support pad and a lower support pad. The heating layer includes a conductive microfilm that has a generally planar shape extending between a front edge, a rear edge, and opposing side edges. In one or more arrangements, the conductive microfilm includes a layer of graphene. In one or more arrangements, the heating mat system has a first electrical contact and a second electrical contact that are connected to the conductive microfilm. When a voltage difference is applied between the first electrical contact and the second electrical contact, current flows through the conductive microfilm, thereby generating heat to the heating mat system and heating livestock positioned on the system.

Abstract: In one or more arrangements, a heating system is provided having one or more heating panels positioned in a housing. The housing has a hollow interior with an open lower end. A first panel is positioned in the open lower end of the housing. The first heating panel includes a heating layer. The heating layer includes a conductive microfilm. A first electrical contact is connected to the conductive microfilm. A second electrical contact is connected to the conductive microfilm. In one or more arrangements, the conductive microfilm includes at least one layer of graphene or nanofiber carbon material. Application of a voltage difference between the first electrical contact and the second electrical contact causes current to flow through the conductive microfilm, thereby generating heat. In one or more arrangements, current which flows through the conductive microfilm causes the conductive microfilm to emit infrared radiation.

Abstract: The present disclosure provides novel cancer therapies. The treatment of cancers harboring EP300 mutations with CREBBP inhibition therapy is described.

Abstract: An electrosurgical unit configured to regulate a RF input signal applied to an electrosurgical device, the electrosurgical unit including a PWM circuit to produce a DC voltage responsive to a control signal; an RF waveform generator configured to generate an RF waveform based at least in part on the DC voltage; a transformer configured to transform the RF waveform to the RF input signal in a forward direction across the isolation barrier and transform a leakage current to a feedback current in a reverse direction across the isolation barrier; and a control circuit configured to generate the control signal based at least in part on the first input signal and the second input signal, the control signal controlling a pulse width modulation of the PWM circuit to produce the RF input signal.

Abstract: Disclosed are fluid delivery lines (“FDLs”) of systems, pads, and methods for targeted temperature management. A system can include a control module, a primary FDL, a secondary FDL, and one or more pads for placement on one or more portions of a patient's body, respectively. The primary FDL can be configured to convey a temperature-controlled fluid as a supply fluid from a hydraulic system of the control module and convey a return fluid back to the hydraulic system. Each pad of the one-or-more pads can include a multilayered pad body including a conduit layer configured to convey the supply fluid therethrough. The secondary FDL can be configured to convey the supply fluid from the primary FDL and convey the return fluid back to the primary FDL. The secondary FDL can include a pair of piercing tips configured to pierce the primary tubing for fluidly connecting the primary and secondary FDLs.

Abstract: Disclosed are systems and methods for performing targeted temperature management including a thermal pad having a thermoelectric device. A pad controller may regulate the temperature of the thermal pad. The thermal pad temperature can facilitate cooling and/or warming of the patient. The pad can include a thermal conduction layer and a skin contact layer. The system may include a controller to set the pad temperature of multiple thermal pads according to a TTM therapy. The thermal pad and the system can incorporate data from temperature sensors coupled to the thermoelectric device and the patient. The system controller may be coupled to the thermal pads via a wired or wireless connection.

Abstract: Disclosed are indicators for confirming fluid connections in systems, pads, and methods thereof for targeted temperature management. For example, a pad can include a multilayered pad body, a pad inlet connector, a pad outlet connector, and an indicator for visual indication of charging a conduit layer of the pad body with a supply fluid and confirmation of accurate fluid connections. The conduit layer includes one or more conduits for conveying a temperature-controlled fluid as the supply fluid from a hydraulic system of a control module as well as convey a return fluid back to the hydraulic system. A thermally conductive adhesive layer over the conduit layer is for placement on a portion of a patient's body. The pad inlet connector includes a pad inlet for charging the conduit layer with the supply fluid. The pad outlet connector includes a pad outlet for discharging the return fluid from the conduit layer.

Abstract: An electrosurgical unit including a radiofrequency generator configured to generate electrosurgical energy. The radiofrequency generator includes a first receptacle configured to electrically couple with an electrosurgical hand piece configured to deliver bipolar radiofrequency energy. A second receptacle is included and configured to electrically couple with an electrosurgical hand piece configured to deliver monopolar radiofrequency energy. The radiofrequency generator includes a relay circuit configured to allow simultaneous radiofrequency energy delivery to the electrosurgical hand pieces in the first receptacle and the second receptacle.

Abstract: Aspects of the present disclosure involve a system comprising a computer-readable storage medium storing at least one program and a method for transforming a motion style of an avatar from a first style to a second style. The program and method include: retrieving, by a processor from a storage device, an avatar depicting motion in a first style; receiving user input selecting a second style; obtaining, based on the user input, a trained machine learning model that performs a non-linear transformation of motion from the first style to the second style; and applying the obtained trained machine learning model to the retrieved avatar to transform the avatar from depicting motion in the first style to depicting motion in the second style.

Abstract: An electrosurgical unit having power monitoring circuitry for reducing leakage current in an electrosurgical unit. The electrosurgical unit includes a power source configured to produce direct current, an RF waveform generator configured to convert the direct current into an RF signal, a voltage sensor configured to measure DC input voltage to the RF waveform generator, a current sensor configured to measure output current feedback, and a processor. The processor is configured to estimate output voltage feedback based at least upon the measured DC input voltage and the measured output current feedback, and output a control signal to control the DC input voltage to the RF waveform generator, the control signal based at least upon the estimated output voltage and the output current feedback.