Abstract: Methodologies in which GAG/collagen mixtures are homogenized into slurries, lyophilized, and dried, have been producing solid matrix products that have favorable tackiness for use in breast reconstruction surgery.

Abstract: Based on dimensions and configurations of a dermal wound on a patient, a carrier is custom-made, preferably by 3D printing, to include a cavity that is duplicative of the specific wound. When the custom-made carrier is used to contain slurry, and the slurry-containing carrier undergoes processing steps (such as freeze-drying in a lyophilization chamber), a matrix is formed that, when removed from the carrier and put into the wound of the patient for whom the carrier was custom-made, fills the wound volume.