Abstract: A catheter having a perfusion section encapsulated by a porous membrane. The catheter can include a shaft to accommodate a radiation source. A spiraled balloon can be positioned about the shaft for centering within a body lumen. Additionally, a longitudinal balloon or mechanical expansion can be provided about the shaft for positioning within a body lumen. A radiotherapy system can be included with a radiation source and a catheter having a perfusion section encapsulated by a porous membrane. A method is provided where a catheter with a perfusion section encapsulated by a porous membrane is advanced through a body lumen. The body lumen is treated by the catheter while a body fluid is perfused past the perfusion section.

Abstract: A multi-lumen balloon for use in a fluted balloon centering catheter and method for providing the same. The multi-lumen balloon maintains a radiation source at the center of a cardiovascular artery, has improved blood perfusion capability, and has improved balloon refolding characteristics. The method of fabricating a multi-lumen balloon designed for a radiation centering catheter uses an improved extrusion process that allows the manufacture of the multi-lumen balloon sub-assembly to be done separately from the catheter shaft assembly.