Patents by Inventor Jessica Kelts

Jessica Kelts has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Protein labeling with cyanobenzothiazole conjugates
    Patent number: 9932365
    Abstract: The invention provides compounds and methods for site-specifically labeling proteins with cyanobenzothiazole derivatives of formula I. For example, the invention provides methods for labeling the N-terminus of a protein that terminates with a cysteine residue. The invention also provides methods for isolating an N-terminally labeled protein and methods for detecting an N-terminally labeled protein.
    Type: Grant
    Filed: June 15, 2017
    Date of Patent: April 3, 2018
    Assignee: PROMEGA CORPORATION
    Inventors: Jessica Kelts, Poncho Meisenheimer, John Shultz
  • PROTEIN LABELING WITH CYANOBENZOTHIAZOLE CONJUGATES
    Publication number: 20170283456
    Abstract: The invention provides compounds and methods for site-specifically labeling proteins with cyanobenzothiazole derivatives of formula I. For example, the invention provides methods for labeling the N-terminus of a protein that terminates with a cysteine residue. The invention also provides methods for isolating an N-terminally labeled protein and methods for detecting an N-terminally labeled protein.
    Type: Application
    Filed: June 15, 2017
    Publication date: October 5, 2017
    Inventors: Jessica Kelts, Poncho Meisenheimer, John Shultz
  • Protein labeling with cyanobenzothiazole conjugates
    Patent number: 9689868
    Abstract: The invention provides compounds and methods for site-specifically labeling proteins with cyanobenzothiazole derivatives of formula I. For example, the invention provides methods for labeling the N-terminus of a protein that terminates with a cysteine residue. The invention also provides methods for isolating an N-terminally labeled protein and methods for detecting an N-terminally labeled protein.
    Type: Grant
    Filed: September 30, 2016
    Date of Patent: June 27, 2017
    Assignee: PROMEGA CORPORATION
    Inventors: Jessica Kelts, Poncho Meisenheimer, John Shultz
  • PROTEIN LABELING WITH CYANOBENZOTHIAZOLE CONJUGATES
    Publication number: 20170016888
    Abstract: The invention provides compounds and methods for site-specifically labeling proteins with cyanobenzothiazole derivatives of formula I. For example, the invention provides methods for labeling the N-terminus of a protein that terminates with a cysteine residue. The invention also provides methods for isolating an N-terminally labeled protein and methods for detecting an N-terminally labeled protein.
    Type: Application
    Filed: September 30, 2016
    Publication date: January 19, 2017
    Inventors: Jessica Kelts, Poncho Meisenheimer, John Shultz
  • Bioluminescent assays using cyanobenzothiazole compounds
    Patent number: 8592172
    Abstract: The invention provides methods that employ derivatives of 2-cyano-6-hydroxy- or 2-cyano-6-amino-benzothiazole, for example, in a bioluminogenic reaction. The invention further provides methods for detecting or determining the presence of molecules and/or enzymes, the modulator activity of such molecules, and/or the activity of such enzymes. The methods are adaptable to high-throughput format.
    Type: Grant
    Filed: March 11, 2011
    Date of Patent: November 26, 2013
    Assignee: Promega Corporation
    Inventors: Jessica Kelts, Poncho Meisenheimer, John Shultz, James J. Cali, Dongping Ma
  • BIOLUMINESCENT ASSAYS USING CYANOBENZOTHIAZOLE COMPOUNDS
    Publication number: 20110223625
    Abstract: The invention provides methods that employ derivatives of 2-cyano-6-hydroxy- or 2-cyano-6-amino-benzothiazole, for example, in a bioluminogenic reaction. The invention further provides methods for detecting or determining the presence of molecules and/or enzymes, the modulator activity of such molecules, and/or the activity of such enzymes. The methods are adaptable to high-throughput format.
    Type: Application
    Filed: March 11, 2011
    Publication date: September 15, 2011
    Applicant: PROMEGA CORPORATION
    Inventors: Jessica Kelts, Poncho Meisenheimer, John Shultz, James J. Cali, Dongping Ma