Patents by Inventor Jessica Liu

Jessica Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel 3-spirocyclic indolyl derivatives useful as ORL-1 receptor modulators
    Publication number: 20070112016
    Abstract: The present invention is directed to novel 3-spirocyclic indolyl derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the ORL-1 receptor.
    Type: Application
    Filed: May 25, 2006
    Publication date: May 17, 2007
    Inventors: Kathleen Battista, Gilles Bignan, Peter Connolly, Jessica Liu, Steven Middleton, Michael Orsini
  • Substituted isoindole-1,3-diones
    Publication number: 20070093500
    Abstract: The present invention relates to substituted isoindole-1,3-dione compounds of Formula (I) and pharmaceutically acceptable forms thereof, as ?1a/?1d adrenoreceptor modulators for the treatment of benign prostatic hypertrophy and lower urinary tract symptoms. The present invention also relates to pharmaceutical compositions comprising said new compounds, new processes to prepare these new compounds and new uses as a medicine as well as methods of treatment.
    Type: Application
    Filed: June 12, 2006
    Publication date: April 26, 2007
    Inventors: George Chiu, Peter Connolly, Jessica Liu, Steven Middleton, Virginia Pulito, Shengjian Li
  • Cyclohexyldiamines as selective alpha 1a/1d adrenoreceptor antagonists for the treatment of benign prostatic hypertrophy and lower urinary tract symptoms
    Publication number: 20060173015
    Abstract: The present invention relates to compounds of Formula (I) or a pharmaceutically acceptable form thereof, as dual selective ?1a/?1d adrenoreceptor antagonists for the treatment of benign prostatic hypertrophy and lower urinary tract symptoms. The present invention also relates to pharmaceutical compositions comprising said new compounds, new processes to prepare these new compounds and new uses as a medicine as well as method of treatments.
    Type: Application
    Filed: October 28, 2005
    Publication date: August 3, 2006
    Inventors: George Chiu, Shengjian Li, Peter Connolly, Virginia Pulito, Jessica Liu, Steven Middleton
  • Procedure for the simultaneous quantitative and qualitative analysis of both flavonoid glycosides and steroidal glycosides
    Patent number: 6635490
    Abstract: A single rapid procedure for the quantitative and qualitative analysis of flavonoid glycosides and steroidal glycosides, in natural products, has been developed. The material is extracted with aqueous solutions of polar organic solvents in an ultrasonic bath. Interfering compounds are removed by pre-purification procedures prior to instrumental analysis by High Pressure Liquid Chromatography with Negative Ion Electrospray Mass Spectrometric Detection and on-line Diode Array Ultraviolet-Visible Spectroscopy. The analysis of flavonoid and steroidal glycosidic compounds in HOSTA leaves served as a model system.
    Type: Grant
    Filed: May 25, 2000
    Date of Patent: October 21, 2003
    Assignee: Noble Laboratories
    Inventors: Kejian Fu, Maciej A. Kaminski, Jessica Liu
  • Methods of treating cancer using flavonoid glycosides and steroidal glycosides
    Publication number: 20020082223
    Abstract: The invention relates to the use of flavonoid glycosides and steroidal glycosides from Hosta or their derivatives as functional ingredients in functional food, OTC and pharmaceutical composition to prevent or treat cancer. The invention further includes methods for making and methods for using the invention.
    Type: Application
    Filed: April 23, 2001
    Publication date: June 27, 2002
    Inventors: Kejian Fu, Jessica Liu, Dong Xie