Patents by Inventor Jessica M. McDaniel

Jessica M. McDaniel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CD28 expression during lenalidomide immune modulation
    Patent number: 10241113
    Abstract: Disclosed are compositions and methods for predicting responsiveness of a subject to treatment with lenalidomide (LEN) by assaying a sample from the subject for surface expression of CD28 on T-cells. Also provided is a method of treating a subject for cancer that involves assaying a sample from the subject for surface expression of CD28 on T-cells and then treating them with LEN if they do not have reduced CD28 surface expression on the T-cells. Also provided is a method for promoting responsiveness of a subject to LEN by administering to the subject a composition that promotes expression of CD28 on the surface of T-cells.
    Type: Grant
    Filed: October 10, 2013
    Date of Patent: March 26, 2019
    Assignee: H. Lee Moffitt Cancer Center and Research Institute, Inc.
    Inventors: Pearlie Burnette, Jessica M. McDaniel
  • CD28 EXPRESSION DURING LENALIDOMIDE IMMUNE MODULATION
    Publication number: 20150276741
    Abstract: Disclosed are compositions and methods for predicting responsiveness of a subject to treatment with lenalidomide (LEN) by assaying a sample from the subject for surface expression of CD28 on T-cells. Also provided is a method of treating a subject for cancer that involves assaying a sample from the subject for surface expression of CD28 on T-cells and then treating them with LEN if they do not have reduced CD28 surface expression on the T-cells. Also provided is a method for promoting responsiveness of a subject to LEN by administering to the subject a composition that promotes expression of CD28 on the surface of T-cells.
    Type: Application
    Filed: October 10, 2013
    Publication date: October 1, 2015
    Inventors: Pearlie Burnette, Jessica M. McDaniel