Patents by Inventor Jessica M. Sido

Jessica M. Sido has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IL-23R antagonists to reprogram intratumoral T regulatory cells into effector cells
    Patent number: 12202904
    Abstract: Provided by the disclosure are compositions and methods for modulating differentiation of regulatory T cells. In some embodiments, methods include selectively decreasing IL-23R activity and/or IL-23R expression without significantly decreasing IL-12R? activity and/or IL-12R? expression.
    Type: Grant
    Filed: February 27, 2023
    Date of Patent: January 21, 2025
    Assignee: DANA-FARBER CANCER INSTITUTE, INC.
    Inventors: Harvey Cantor, Hye-Jung Kim, Jessica M. Sido
  • IL-23R ANTAGONISTS TO REPROGRAM INTRATUMORAL T REGULATORY CELLS INTO EFFECTOR CELLS
    Publication number: 20230406944
    Abstract: Provided by the disclosure are compositions and methods for modulating differentiation of regulatory T cells. In some embodiments, methods include selectively decreasing IL-23R activity and/or IL-23R expression without significantly decreasing IL-12RP activity and/or IL-12RP expression.
    Type: Application
    Filed: February 27, 2023
    Publication date: December 21, 2023
    Inventors: Harvey Cantor, Hye-Jung Kim, Jessica M. Sido
  • IL-23R antagonists to reprogram intratumoral T regulatory cells into effector cells
    Patent number: 11591403
    Abstract: Provided by the disclosure are compositions and methods for modulating differentiation of regulatory T cells. In some embodiments, methods include selectively decreasing IL-23R activity and/or IL-23R expression without significantly decreasing IL-12RP activity and/or IL-12RP expression.
    Type: Grant
    Filed: May 2, 2018
    Date of Patent: February 28, 2023
    Assignee: Dana-Farber Cancer Institute, Inc.
    Inventors: Harvey Cantor, Hye-Jung Kim, Jessica M. Sido
  • IL-23R ANTAGONISTS TO REPROGRAM INTRATUMORAL T REGULATORY CELLS INTO EFFECTOR CELLS
    Publication number: 20210040220
    Abstract: Provided by the disclosure are compositions and methods for modulating differentiation of regulatory T cells. In some embodiments, methods include selectively decreasing IL-23R activity and/or IL-23R expression without significantly decreasing IL-12RP activity and/or IL-12RP expression.
    Type: Application
    Filed: May 2, 2018
    Publication date: February 11, 2021
    Applicant: Dana-Farber Cancer Institute, Inc.
    Inventors: Harvey Cantor, Hye-Jung Kim, Jessica M. Sido
  • IL-23R ANTAGONISTS TO REPROGRAM INTRATUMORAL T REGULATORY CELLS INTO EFFECTOR CELLS
    Publication number: 20200055945
    Abstract: Provided by the disclosure are compositions and methods for modulating differentiation of regulatory T cells. In some embodiments, methods include selectively decreasing IL-23R activity and/or IL-23R expression without significantly decreasing IL-12RP activity and/or IL-12RP expression.
    Type: Application
    Filed: May 2, 2018
    Publication date: February 20, 2020
    Applicant: Dana-Farber Cancer Institute, Inc.
    Inventors: Harvey Cantor, Hye-Jung Kim, Jessica M. Sido