Patents by Inventor Jessica McGrath

Jessica McGrath has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of thermophilic nucleases for degrading nucleic acids
    Patent number: 10385308
    Abstract: The present invention relates to the use of a thermophilic nuclease for degrading nucleic acids in vivo and/or in situ, wherein the thermophilic nuclease is heterologous to the host cell and is produced by the host rather than being added exogenously. The present invention further relates to a genetically modified cell which was produced according to the above method. The present invention is particularly beneficial in inactivating the biological activity of recombinant DNA in biomass or biomass-derived products.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: August 20, 2019
    Assignee: DSM IP Assets B.V.
    Inventors: Joshua Trueheart, Jessica McGrath
  • Engineering resistance to aliphatic alcohols
    Patent number: 8906666
    Abstract: The present disclosure provides improved systems for the biological production of aliphatic alcohol compounds. In particular, the present disclosure provides biological systems that show improved resistance to aliphatic alcohol toxicity; in some embodiments, such improved resistance allows for increased levels of aliphatic alcohol production. In one aspect, the present disclosure provides engineered microorganisms that both produce an aliphatic alcohol compound and show resistance to that compound as measured by an ability to grow to predetermined levels in the presence of a given concentration of the compound.
    Type: Grant
    Filed: May 22, 2009
    Date of Patent: December 9, 2014
    Assignee: Butamax Advanced Biofuels LLC
    Inventors: Keith Alsaker, Daniel Grenfell-Lee, Michael Hudson, Adam Lawrence, Jessica McGrath, David Young
  • ENGINEERING RESISTANCE TO ALIPHATIC ALCOHOLS
    Publication number: 20120058541
    Abstract: The present disclosure provides improved systems for the biological production of certain aliphatic alcohol compounds. In particular, the present disclosure provides biological systems that show improved resistance to aliphatic alcohol toxicity; in sonic embodiments, such improved resistance allows for increased levels of aliphatic alcohol production. Accordingly, the present disclosure provides, inter alia, engineered microorganisms that both produce an aliphatic alcohol compound and show resistance to that compound as measured by an ability to grow to predetermined levels in the presence of a given concentration of the compound.
    Type: Application
    Filed: August 22, 2011
    Publication date: March 8, 2012
    Applicant: BUTAMAX(TM) ADVANCED BIOFUELS LLC
    Inventors: Keith Alsaker, Daniel Grenfell-Lee, Michael Hudson, Adam Lawrence, Jessica McGrath, David Young
  • ENGINEERING RESISTANCE TO ALIPHATIC ALCOHOLS
    Publication number: 20120040440
    Abstract: The present disclosure provides improved systems for the biological production of aliphatic alcohol compounds. In particular, the present disclosure provides biological systems that show improved resistance to aliphatic alcohol toxicity; in some embodiments, such improved resistance allows for increased levels of aliphatic alcohol production. In one aspect, the present disclosure provides engineered microorganisms that both produce an aliphatic alcohol compound and show resistance to that compound as measured by an ability to grow to predetermined levels in the presence of a given concentration of the compound.
    Type: Application
    Filed: May 22, 2009
    Publication date: February 16, 2012
    Inventors: Keith Alsaker, Daniel Grenfell-Lee, Michael Hudson, Adam Lawrence, Jessica McGrath, David Young