Abstract: A biopsy device includes a body portion, a cannula, a cutter, and a tissue stop having a proximal face. The cannula has a transverse aperture that is defined in part by a proximal edge and a distal edge. The cutter is movable to a distal position to sever tissue protruding through the transverse aperture. A tip at the distal end of the cannula has a sharp edge that extends proximally to a longitudinal position that is proximal to the longitudinal position of the distal edge of the transverse aperture. The sharp edge of the tip extends to a longitudinal position that is proximal to the longitudinal position of the distal cutting edge of the cutter when the cutter is at the distal position. The sharp edge of the tip extends to a longitudinal position that is proximal to the longitudinal position of the proximal face of the tissue stop.

Abstract: A biopsy marker delivery device are described. The delivery device can include a relatively flexible hollow tube, a pushing member such as a push rod disposed for sliding with the tube, and at least one marker disposed in the tube. The push rod can include a surface feature effective for reducing the contact area of the push rod with the internal surface of the hollow tube. The surface feature can be effective for reducing binding of the push rod within the hollow tube when the tube and rod are subject to bending.

Abstract: A biopsy system comprises a control module, a localization assembly, a biopsy device, and a targeting cube. The biopsy device comprises a probe and other components, which selectively couple with a targeting cube that is configured to selectively couple with a grid plate having apertures for receiving the targeting cube. The targeting cube comprises a body defined by faces. The targeting cube further comprises guide holes that originate and terminate at the faces and pass through the body of the targeting cube to provide passageways through the targeting cube. The faces of the targeting cube comprise a tapered profile from a proximal end to a distal end. The tapered profile of the targeting cube may be created by the faces themselves or by protruding elements from the faces. The body of the targeting cube and/or the protruding elements may be at least partially comprised of an elastomeric material.

Abstract: A biopsy system comprises a control module, a localization assembly, a biopsy device, and a targeting cube. The biopsy device comprises a probe and other components, which selectively couple with a targeting cube that is configured to selectively couple with a grid plate having apertures for receiving the targeting cube. The targeting cube comprises a body defined by faces, and guide holes that originate and terminate at the faces and pass through the body of the targeting cube to provide passageways through the targeting cube. The body of the targeting cube is at least partially comprised of elastomeric material to allow for adjustment of the orientation of the passageways. The body of the targeting cube is further comprised of malleable members that flank the passageways and allow for angulation of an instrument, such as by maintaining an adjusted orientation of a passageway into which the instrument is inserted.

Abstract: A biopsy system comprises a control module, a localization assembly, a biopsy device, and a targeting cube. The biopsy device comprises a holster portion and a probe. The probe and/or other associated components are configured to selectively couple with a targeting cube that is configured to selectively couple with a grid plate having apertures for receiving the targeting cube. The targeting cube comprises a body defined by faces. The targeting cube further comprises guide holes that originate and terminate at the faces and pass through the body of the targeting cube to provide a passageway through the targeting cube. The body of the targeting cube is at least partially comprised of elastomeric material to allow for compression of the body. The elastomeric material may thus provide a secure fit with a wide range of grid plates having openings of various shapes and sizes.

Abstract: A biopsy system comprises a control module, a localization assembly, a biopsy device, and a targeting cube. The biopsy device comprises a holster portion and a probe. The probe and/or other associated components are configured to selectively couple with a targeting cube that is configured to selectively couple with a grid plate having apertures for receiving the targeting cube. The targeting cube comprises a body defined by faces. The targeting cube further comprises guide holes that originate and terminate at the faces and pass through the body of the targeting cube to provide passageways through the targeting cube. The intersections of the faces of the targeting cube comprise edges that are comprised of elastomeric material. The elastomeric edges allow for compression and may thus provide a secure fit with a wide range of grid plates having openings of various shapes and sizes.

Abstract: A biopsy system comprises a control module, a localization assembly, a biopsy device, and a targeting cube. The biopsy device comprises a holster portion and a probe. The probe and/or other associated components are configured to selectively couple with a targeting cube, where the targeting cube is configured to selectively couple with a grid plate having apertures for receiving the targeting cube. The targeting cube comprises a body defined by faces. The targeting cube further comprises guide holes that originate and terminate at the faces and pass through the body of the targeting cube to provide passageways through the targeting cube. The targeting cube further comprises at least one hinged member positioned along the outer portion of the targeting cube and interfacing with an aperture in the grid plate. The hinged member may provide a tapered profile to the targeting cube and may further comprise an elastomeric portion.

Abstract: A support assembly is configured to support a biopsy device. The biopsy device has a probe portion coupled with a holster portion. The probe portion may have an integral or removable needle. The holster portion has a mounting recess and a pair of distally extending mounting arms. The support assembly comprises a cradle and a mount. The cradle has a rail that complements the mounting recess of the holster portion. The mount is configured to move longitudinally along the rail. The mount has a pair of recesses that complement the pair of distally extending mounting arms of the holster portion. A cannula support member may be located at the distal end of the cradle. The cradle, mount, and cannula support may collectively support and stabilize the biopsy device in a rigid fashion. The cradle may be coupled with a targeting assembly such as a grid or pedestal.

Abstract: A biopsy device comprises a targeting set assembly, a probe assembly, and a holster assembly, which are detachable from one another. The targeting set assembly comprises a needle assembly, which comprises a connecting member. The probe assembly comprises components configured to selectively attach to the connecting member of the needle assembly. In some versions, the connecting member comprises a recess, and the probe assembly comprises a protrusion configured to selectively engage the recess. The protrusion may be provided on a rocking member or on a resilient arm. The rocking member or resilient arm may bias the protrusion to enter the recess. The connection of the probe assembly to needle assembly provides a device for use during a biopsy procedure. The connection of the probe assembly to needle assembly may further permit rotation of the needle assembly for indexing.

Abstract: A biopsy system includes a first external device, a second external device and a control module interface. The control module interface is in electrical communication with both the first and second external devices, and the control module interface is in mechanical communication with the second external device. The control module interface is configured to be positioned remotely from at least one of the first and second external devices. The control module interface comprises a motor, operational electronics, a shaft connector assembly, an electrical connector and a cabinet configured to house the motor and operational electronics. The motor is in mechanical communication with the second external device via a mechanical cable. The operational electronics are configured to permit control of the motor and a motorized component of the second external device. In some embodiments, the mechanical cable comprises a flexible shaft cable, such as a speedometer cable.

Abstract: A biopsy device comprises a targeting set assembly, a probe assembly, and a holster assembly, which are detachable from one another. The targeting set assembly comprises a needle assembly having a tissue piercing tip and tissue receiving aperture. The needle assembly further comprises a needle portion, a needle hub, and a connecting member. The connecting member permits attachment of the needle assembly to the probe assembly. The needle portion may include one or more ceramic inserts, and further is provided with a dual lumen structure. The needle hub comprises features to permit access to the dual lumen structure of the needle portion, while managing fluid and vacuum within the device.

Abstract: A cradle assembly is configured to support a biopsy device. The cradle assembly comprises first support member and a second support member. A biopsy device may be supported by either the first support member or the second support member. A movement restriction member is operable to restrict the longitudinal distance to which a biopsy device may be advanced relative to the cradle assembly. The movement restriction member may comprise a needle mount, a cannula mount, and/or a z-stop. For instance, a z-stop may be positioned to limit the distance to which a cannula mount may be slid along a rail of the cradle. A screw gear may be used to make fine adjustments to the longitudinal position of the z-stop. A needle mount or cannula mount may also include a ratcheting mechanism to restrict proximal motion of the needle mount or cannula mount along a rail of the cradle.

Abstract: A biopsy device comprises a probe and a holster. The probe has a distally extending needle and a central thumbwheel coupled with the needle. The needle has a transverse tissue receiving aperture. A cutter is translatable relative to the needle to sever tissue protruding through the aperture. The central thumbwheel is manually operable to rotate the needle to reorient the angular position of the aperture about the longitudinal axis defined by the needle. The central thumbwheel is positioned coaxially with the longitudinal axis. An elongate sleeve unitarily couples the needle with the central thumbwheel. A cable driven mechanism in the holster drives the cutter. A rotatable tissue sample holder is coupled with the probe, and has chambers configured to receive tissue samples communicated proximally through a lumen defined by the cutter. A piezoelectric motor in the holster drives the tissue sample holder.

Abstract: A biopsy device targeting set includes a vertical member, a carriage that is vertically movable along the vertical member, and a cradle coupled with the carriage. The cradle has a pair of substantially perpendicular mounting arms. Each mounting arm has a recess that may receive a rail of the carriage, such that the cradle may be mounted to the same rail in different orientations. Each mounting arm also has a biopsy device mounting feature, which may be a recess or a rail. The biopsy device mounting feature is configured to engage with a complementary feature of a biopsy device, such that a biopsy device may be mounted to either mounting arm. A z-stop feature is operable to selectively restrict longitudinal motion along either or both of the biopsy device mounting features. The targeting set may be used with a biopsy device in an MRI environment.

Abstract: Biopsy devices and methods useful with Positron Emission Tomography (PET) and Breast Specific Gamma Imaging (BSGI) are disclosed. A biopsy device including a flexible tube having a side aperture, and a PET or BSGI imageable material disposed within the flexible tube is disclosed. A biopsy method is disclosed that includes advancing a flexible tube having a PET or BSGI imageable material distally through the biopsy device. Various other embodiments and applications are disclosed.

Abstract: Biopsy devices and methods useful with Positron Emission Tomography (PET) and Breast Specific Gamma Imaging (BSGI) are disclosed. A biopsy device including a flexible tube having a side aperture, and a PET or BSGI imageable material disposed within the flexible tube is disclosed. A biopsy method is disclosed that includes advancing a flexible tube having a PET or BSGI imageable material distally through the biopsy device. Various other embodiments and applications are disclosed.

Abstract: Biopsy devices and methods useful with Positron Emission Tomography (PET) and Breast Specific Gamma Imaging (BSGI) are disclosed. A biopsy device including a flexible tube having a side aperture, and a PET or BSGI imageable material disposed within the flexible tube is disclosed. A biopsy method is disclosed that includes advancing a flexible tube having a PET or BSGI imageable material distally through the biopsy device. Various other embodiments and applications are disclosed.

Abstract: A biopsy probe includes a body portion, a cannula, a tip, and a cutter. The cannula extends relative to the body portion. The cannula has a first lumen configured to receive a cutter and a transverse aperture configured to receive tissue. The cutter is disposed in the first lumen of the cannula, and is configured to translate relative to the cannula. The tip is located on the distal end of the cannula. An opening is formed through the tip. A second lumen extends through the cannula, and is in fluid communication with the opening formed in the tip. Substances or liquids such as medicine may be dispensed to a biopsy site or other location within the body of a patient via the second lumen and the opening in the tip. The second lumen may be fluidly isolated from the first lumen and any other lumen in the cannula.