Patents by Inventor Jessica Pax

Jessica Pax has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF MANUFACTURING A HIGH MOLECULAR WEIGHT HEPARIN COMPOUND
    Publication number: 20230321137
    Abstract: A method of manufacturing a high molecular weight heparin (HMWH) compound is disclosed. The method comprises dissolving heparin to form a heparin solution and fractionating the heparin solution via tangential flow filtration (TFF) using a membrane with a molecular weight cut off (MWCO) between about 8 kDa and about 12 kDa. The TFF yields a retentate comprising fractionated heparin with a weight average molecular weight of about 20 kDa or greater, i.e., a high molecular weight heparin compound. A substantial proportion of heparin chains in the fractionated heparin may have a high molecular weight, e.g., 50% of the heparin chains or greater may have a molecular weight of 20 kDa or greater.
    Type: Application
    Filed: June 12, 2023
    Publication date: October 12, 2023
    Applicant: NexEos Diagnostics, Inc.
    Inventors: Li FU, Zhenyu WANG, Jessica PAX
  • Methods of manufacturing a high molecular weight heparin compound
    Patent number: 11712447
    Abstract: A method of manufacturing a high molecular weight heparin (HMWH) compound is disclosed. The method comprises dissolving heparin to form a heparin solution and fractionating the heparin solution via tangential flow filtration (TFF) using a membrane with a molecular weight cut off (MWCO) between about 8 kDa and about 12 kDa. The TFF yields a retentate comprising fractionated heparin with a weight average molecular weight of about 20 kDa or greater, i.e., a high molecular weight heparin compound. A substantial proportion of heparin chains in the fractionated heparin may have a high molecular weight, e.g., 50% of the heparin chains or greater may have a molecular weight of 20 kDa or greater.
    Type: Grant
    Filed: May 12, 2022
    Date of Patent: August 1, 2023
    Assignee: NexEos Diagnostics, Inc.
    Inventors: Li Fu, Zhenyu Wang, Jessica Pax
  • METHODS OF MANUFACTURING A HIGH MOLECULAR WEIGHT HEPARIN COMPOUND
    Publication number: 20220362283
    Abstract: A method of manufacturing a high molecular weight heparin (HMWH) compound is disclosed. The method comprises dissolving heparin to form a heparin solution and fractionating the heparin solution via tangential flow filtration (TFF) using a membrane with a molecular weight cut off (MWCO) between about 8 kDa and about 12 kDa. The TFF yields a retentate comprising fractionated heparin with a weight average molecular weight of about 20 kDa or greater, i.e., a high molecular weight heparin compound. A substantial proportion of heparin chains in the fractionated heparin may have a high molecular weight, e.g., 50% of the heparin chains or greater may have a molecular weight of 20 kDa or greater.
    Type: Application
    Filed: May 12, 2022
    Publication date: November 17, 2022
    Applicant: NexEos Diagnostics, Inc.
    Inventors: Li Fu, Zhenyu Wang, Jessica Pax