Patents by Inventor Jesus Avila De Grado

Jesus Avila De Grado has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical Compositions for the Treatment of Neurodegenerative Disorders
    Publication number: 20080206356
    Abstract: Pharmaceutical compositions comprising an effective amount of a tungsten (VI) compound, preferably of a tungstate salt, and more preferably of sodium tungstate (Na2WO4), are useful for the prophylactic and/or therapeutical treatment of neurodegenerative disorders in a mammal, including a human, in particular, for the prophylactic and/or therapeutical treatment of Alzheimer's disease or schizophrenia. The effect of sodium tungstate dihydrate on the phosphorylation of tau in a model of rat insulin resistance and in a model of type-1 diabetes has been assessed. The therapeutic treatment of tauopathies that derives from this invention involves several advantages: it targets a GSK3; specificity since it reduces the abnormal hyperphosphorylation of a neural specific protein, tau, efficacy, lack of toxicity, and low price.
    Type: Application
    Filed: July 28, 2006
    Publication date: August 28, 2008
    Applicants: UNIVERSIDAD DE BARCELONA, CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
    Inventors: Joan Josep Guinovart Cirera, Jesus Avila De Grado, Jorge Dominguez Reyes, Ramon Gomis De Barbara, Alberto Gomez Ramos, Delia Zafra Lopez, Helena Corominola Ocana
  • GSK-3? expressed in a transgenic mouse
    Patent number: 7265259
    Abstract: A transgenic animal in which GSK-3? protein is over-expressed is useful as a model for neurodegenerative disease.
    Type: Grant
    Filed: May 18, 2001
    Date of Patent: September 4, 2007
    Assignees: Consejo Superior de Investigaciones Clentificas, Universidad Autonoma de Madrid (UAM)
    Inventors: Félix Hernandez Perez, Jesús Avila De Grado, José Javier Lucas Lozano
  • Model for neurodegenerative disease
    Publication number: 20030177510
    Abstract: A transgenic animal in which GSK-3&bgr; protein is over-expressed is useful as a model for neurodegenerative disease.
    Type: Application
    Filed: May 19, 2003
    Publication date: September 18, 2003
    Inventors: Felix Hernandez Perez, Jesus Avila De Grado, Jose Javier Lucas Lozano