Patents by Inventor Jesus G. Valenzuela

Jesus G. Valenzuela has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • polypeptides and methods of use
    Patent number: 10314900
    Abstract: Substantially purified salivary Lu. longipalpis polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the Lu. longipalpis polynucleotides are also disclosed. In one embodiment, a method is disclosed for inducing an immune response to sand fly saliva. In other embodiments, methods for treating, diagnosing, or preventing Leishmaniasis are disclosed.
    Type: Grant
    Filed: January 9, 2018
    Date of Patent: June 11, 2019
    Assignees: The United States of America, as represted by the Secretary, Department of Health and Human Services, Fundaçao Oswaldo Cruz (FIOCRUZ)
    Inventors: Jesus G. Valenzuela, Jose M. C. Ribeiro, Aldina Barral, Manoel Barral Netto, Claudia I. Brodskyn, Regis Gomes
  • LUTZOMYIA LONGIPALPIS POLYPEPTIDES AND METHODS OF USE
    Publication number: 20180147269
    Abstract: Substantially purified salivary Lu. longipalpis polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the Lu. longipalpis polynucleotides are also disclosed. In one embodiment, a method is disclosed for inducing an immune response to sand fly saliva. In other embodiments, methods for treating, diagnosing, or preventing Leishmaniasis are disclosed.
    Type: Application
    Filed: January 9, 2018
    Publication date: May 31, 2018
    Applicants: The Government of the United States of America as represented by the Secretary of the Department of, Fundaçao Oswaldo Cruz (FIOCRUZ)
    Inventors: Jesus G. Valenzuela, Jose M.C. Ribeiro, Aldina Barral, Manoel Barral Netto, Claudia I. Brodskyn, Regis Gomes
  • polypeptides and methods of use
    Patent number: 9884100
    Abstract: Substantially purified salivary Lu. longipalpis polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the Lu. longipalpis polynucleotides are also disclosed. In one embodiment, a method is disclosed for inducing an immune response to sand fly saliva. In other embodiments, methods for treating, diagnosing, or preventing Leishishmaniasis are disclosed.
    Type: Grant
    Filed: June 7, 2016
    Date of Patent: February 6, 2018
    Assignees: The United States of America as represented by the Secretary of the Department of Health and Human Services, Fundacão Oswaldo Cruz (FIOCRUZ)
    Inventors: Jesus G. Valenzuela, Jose M. C. Ribeiro, Aldina Barral, Manoel Barral Netto, Claudia I. Brodskyn, Regis Gomes
  • LUTZOMYIA LONGIPALPIS POLYPEPTIDES AND METHODS OF USE
    Publication number: 20160279211
    Abstract: Substantially purified salivary Lu. longipalpis polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the Lu. longipalpis polynucleotides are also disclosed. In one embodiment, a method is disclosed for inducing an immune response to sand fly saliva. In other embodiments, methods for treating, diagnosing, or preventing Leishishmaniasis are disclosed.
    Type: Application
    Filed: June 7, 2016
    Publication date: September 29, 2016
    Applicants: The Government of the U.S.A. as represented by the Secretary of the Department of Health and Human S, Fundaçao Oswaldo Cruz (FIOCRUZ)
    Inventors: Jesus G. Valenzuela, Jose M.C. Ribeiro, Aldina Barral, Manoel Barral Netto, Claudia I. Brodskyn, Regis Gomes
  • polypeptides and methods of use
    Patent number: 9382302
    Abstract: Substantially purified salivary Lu. longipalpis polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the Lu. longipalpis polynucleotides are also disclosed. In one embodiment, a method is disclosed for inducing an immune response to sand fly saliva. In other embodiments, methods for treating, diagnosing, or preventing Leishmaniasis are disclosed.
    Type: Grant
    Filed: July 17, 2015
    Date of Patent: July 5, 2016
    Assignees: The United States of America as represented by the Secretary of the Department of Health and Human Services, Fundação Oswaldo Cruz (FIOCRUZ)
    Inventors: Jesus G. Valenzuela, Jose M. C. Ribeiro, Aldina Barral, Manoel Barral Netto, Claudia I. Brodskyn, Regis Gomes
  • LUTZOMYIA LONGIPALPIS POLYPEPTIDES AND METHODS OF USE
    Publication number: 20150315254
    Abstract: Substantially purified salivary Lu. longipalpis polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the Lu. longipalpis polynucleotides are also disclosed. In one embodiment, a method is disclosed for inducing an immune response to sand fly saliva. In other embodiments, methods for treating, diagnosing, or preventing Leishmaniasis are disclosed.
    Type: Application
    Filed: July 17, 2015
    Publication date: November 5, 2015
    Applicants: The Government of the United States of America as represented by the Secretary of the Department of, Fundacao Oswaldo Cruz (FIOCRUZ)
    Inventors: Jesus G. Valenzuela, Jose M.C. Ribeiro, Aldina Barral, Manoel Barral Netto, Claudia I. Brodskyn, Regis Gomes
  • polypeptides and methods of use
    Patent number: 9120867
    Abstract: Substantially purified salivary Lu. longipalpis polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the Lu. longipalpis polynucleotides are also disclosed. In one embodiment, a method is disclosed for inducing an immune response to sand fly saliva. In other embodiments, methods for treating, diagnosing, or preventing Leishmaniasis are disclosed.
    Type: Grant
    Filed: December 5, 2013
    Date of Patent: September 1, 2015
    Assignees: The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: Jesus G. Valenzuela, Jose M. C. Ribeiro, Aldina Barral, Manoel Netto, Claudia I. Brodskyn, Regis Gomes
  • LUTZOMYIA LONGIPALPIS POLYPEPTIDES AND METHODS OF USE
    Publication number: 20140093531
    Abstract: Substantially purified salivary Lu. longipalpis polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the Lu. longipalpis polynucleotides are also disclosed. In one embodiment, a method is disclosed for inducing an immune response to sand fly saliva. In other embodiments, methods for treating, diagnosing, or preventing Leishmaniasis are disclosed.
    Type: Application
    Filed: December 5, 2013
    Publication date: April 3, 2014
    Applicants: Fundacao Oswaldo Cruz (FIOCRUZ), The Government of the United States of America as represented by the Secretary of the Department of
    Inventors: Jesus G. Valenzuela, Jose M.C. Ribeiro, Aldina Barral, Manoel Netto, Claudia I. Brodskyn, Regis Gomes
  • Lutzomyia longipalpis polypeptides and methods of use
    Patent number: 8628780
    Abstract: Substantially purified salivary Lu. longipalpis polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the Lu. longipalpis polynucleotides are also disclosed. In one embodiment, a method is disclosed for inducing an immune response to sand fly saliva. In other embodiments, methods for treating, diagnosing, or preventing Leishmaniasis are disclosed.
    Type: Grant
    Filed: January 7, 2009
    Date of Patent: January 14, 2014
    Assignees: The United States of America as represented by the Secretary of the Department of Health and Human Services, Fundação Oswaldo Cruz (FIOCRUZ)
    Inventors: Jesus G. Valenzuela, Jose M. C. Ribeiro, Aldina Barral, Manoel Netto, Claudia Brodskyn, Regis Gomes
  • Anti-arthropod vector vaccines, methods of selecting and uses thereof
    Patent number: 8629260
    Abstract: The present disclosure provides methods of selecting and uses of anti-arthropod vector vaccines to prevent Leishmaniasis. The present disclosure also provides compositions for vaccines to prevent Leishmaniasis.
    Type: Grant
    Filed: December 11, 2012
    Date of Patent: January 14, 2014
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: Jesus G. Valenzuela, Yasmine Belkaid, Shaden Kamhawi, David Sacks, Jose M.C. Ribeiro
  • vaccine using sand fly salivary immunogen
    Patent number: 8603808
    Abstract: The present invention provides vectors that contain and express in vivo or in vitro sand fly Lu. longipalpis salivary antigens that elicit an immune response in animal or human against Leishmania, vaccine compositions comprising said vectors and/or Lu. longipalpis salivary polypeptides, methods of vaccination against Leishmania, and kits for use with such methods and compositions.
    Type: Grant
    Filed: May 6, 2009
    Date of Patent: December 10, 2013
    Assignees: Merial Limited, The United States of America As Represented by The Secretary of the Department of Health and Human Services
    Inventors: Laurent Bernard Fischer, Jesus G. Valenzuela, Jose Ribeiro, Shaden Kamhawi
  • Anti-arthropod vector vaccines, methods of selecting and uses thereof
    Patent number: 8343499
    Abstract: The present invention provides methods of selecting and uses of anti-arthropod vector vaccines to prevent Leishmaniasis. The present invention also provides compositions for vaccines to prevent Leishmaniasis.
    Type: Grant
    Filed: May 6, 2011
    Date of Patent: January 1, 2013
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: Jesus G. Valenzuela, Yasmine Belkaid, Shaden Kamhawi, David Sacks, Jose M. C. Ribeiro
  • ANTI-ARTHROPOD VECTOR VACCINES, METHODS OF SELECTING AND USES THEREOF
    Publication number: 20110212134
    Abstract: The present invention provides methods of selecting and uses of anti-arthropod vector vaccines to prevent Leishmaniasis. The present invention also provides compositions for vaccines to prevent Leishmaniasis.
    Type: Application
    Filed: May 6, 2011
    Publication date: September 1, 2011
    Inventors: Jesus G. Valenzuela, Yasmine Belkaid, Shaden Kamhawi, David Sacks, Jose M.C. Ribeiro
  • Anti-arthropod vector vaccines, methods of selecting and uses thereof
    Patent number: 7964576
    Abstract: The present invention provides methods of selecting and uses of anti-arthropod vector vaccines to prevent Leishmaniasis. The present invention also provides compositions for vaccines to prevent Leishmaniasis.
    Type: Grant
    Filed: April 9, 2008
    Date of Patent: June 21, 2011
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: Jesus G. Valenzuela, Yasmine Belkaid, Shaden Kamhawi, David Sacks, Jose M. C. Ribeiro
  • Methods for Detection and Prevention of Tick Infestation and Pathogen Transmission
    Publication number: 20100278752
    Abstract: The invention generally features methods for the prevention and detection of a tick infestation. The present invention also features methods for decreasing the ability of a tick to feed on a subject.
    Type: Application
    Filed: July 25, 2008
    Publication date: November 4, 2010
    Applicant: Rhode Island Board of Governors for Higher Education
    Inventors: Michail Kotsyfakis, Jose M.C. Ribeiro, Jesus G. Valenzuela, John F. Andersen, Jennifer M. Anderson, Shahid Karim, Thomas N. Mather
  • P. ARIASI POLYPEPTIDES, P. PERNICIOSUS POLYPEPTIDES AND METHODS OF USE
    Publication number: 20100196381
    Abstract: Substantially purified salivary P. ariasi and P. perniciosus polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the P. ariasi and P. perniciosus polynucleotides are also disclosed. In one embodiment, a method is disclosed for inducing an immune response to sand fly saliva. In other embodiments, methods for treating or preventing Leishmaniasis are disclosed.
    Type: Application
    Filed: April 13, 2010
    Publication date: August 5, 2010
    Inventors: Jesus G. Valenzuela, Jose M.C. Ribiero, Shaden Kamhawi, Yasmine Belkaid, Laurent Fischer, Jean-Christophe Audonnet, Francis Milward
  • polypeptides, polypeptides and methods of use
    Patent number: 7741437
    Abstract: Substantially purified salivary P. ariasi and P. perniciosus polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the P. ariasi and P. perniciosus polynucleotides are also disclosed. In one embodiment, a method is disclosed for inducing an immune response to sand fly saliva. In other embodiments, methods for treating or preventing Leishmaniasis are disclosed.
    Type: Grant
    Filed: September 18, 2003
    Date of Patent: June 22, 2010
    Assignees: The United States of America as represented by the Department of Health and Human Services, Merial Limited
    Inventors: Jesus G. Valenzuela, Jose M. C. Ribiero, Shaden Kamhawi, Yasmine Belkaid, Laurent Fischer, Jean-Christophe Audonnet, Francis Milward
  • LEISHMANIA VACCINE USING SAND FLY SALIVARY IMMUNOGEN
    Publication number: 20090324649
    Abstract: The present invention provides vectors that contain and express in vivo or in vitro sand fly Lu. longipalpis salivary antigens that elicit an immune response in animal or human against Leishmania, vaccine compositions comprising said vectors and/or Lu. longipalpis salivary polypeptides, methods of vaccination against Leishmania, and kits for use with such methods and compositions.
    Type: Application
    Filed: May 6, 2009
    Publication date: December 31, 2009
    Inventors: Laurent Bernard Fischer, Jesus G. Valenzuela, Jose Ribeiro, Shaden Kamhawi
  • LUTZOMYIA LONGIPALPIS POLYPEPTIDES AND METHODS OF USE
    Publication number: 20090117139
    Abstract: Substantially purified salivary Lu. longipalpis polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the Lu. longipalpis polynucleotides are also disclosed. In one embodiment, a method is disclosed for inducing an immune response to sand fly saliva. In other embodiments, methods for treating, diagnosing, or preventing Leishmaniasis are disclosed.
    Type: Application
    Filed: January 7, 2009
    Publication date: May 7, 2009
    Inventors: Jesus G. Valenzuela, Jose M.C. Ribeiro, Aldina Barral, Manoel Netto, Claudia Brodskyn, Regis Gomes
  • Anti-arthropod vector vaccines, methods of selecting and uses thereof
    Publication number: 20090053255
    Abstract: The present invention provides methods of selecting and uses of anti-arthropod vector vaccines to prevent Leishmaniasis. The present invention also provides compositions for vaccines to prevent Leishmaniasis.
    Type: Application
    Filed: April 9, 2008
    Publication date: February 26, 2009
    Inventors: Jesus G. Valenzuela, Yasmine Belkaid, Shaden Kamhawi, David Sacks, Jose M.C. Ribeiro