Abstract: Pharmaceutical composition comprising growth-hormone releasing peptide 6 (GHRP-6), tartrate buffer at pH 5.0-6.0, and trehalose as stabilizing agent, as well as the use of said composition for the manufacture of a medicament. The invention also provides a kit of parts comprising said pharmaceutical composition and a method of treatment of an individual in need thereof, which entails the administration of a therapeutically effective amount of the pharmaceutical composition comprising of GHRP-6, tartrate buffer at pH 5.0-6.0 and trehalose.

Abstract: This invention describes ways of obtaining nano-particulated adjuvants formed by different synthetic variants of GM3 ganglioside. Depending on the fine structure of the fatty acid in the ceramide of the synthetic GM3, said adjuvants are able to stimulate specifically and in a specialized way the humoral or cellular immune response against accompanying antigens. Particularly, this invention provides immunogenic vaccine compositions that comprise peptides, polypeptides or proteins and the aforementioned nanoparticles, which are formed through the dispersion of hydrophobic proteins of the outer membrane complex (OMC) of Neisseria meningitidis in solutions containing fully synthetic variants of the GM3 ganglioside.

Abstract: Systems and methods for generation and use of vendor management platform architectures are disclosed. A compliance component may be utilized to receive user input data indicating supply contracts between a client and a vendor. The user input data may be utilized to determine insurable obligations associated with the supply contract and provide indications as to whether or not the vendor is compliant with the insurable obligation required by the supply contract. An exposure assessment component may be utilized to determine an exposure score associated with a client account and/or a vendor account based on various compliance factors, spending amounts, and/or properties associated with at least one of goods and/or services that a vendor will supply to a client.

Abstract: The invention relates to an immunogenic or vaccine composition comprising an inactivated bacterium from the species Brachyspira hyodysenteriae, to a method for producing said composition and to the medical use of this composition for inducing an immune response against a bacterium from the species Brachyspira hyodysenteriae or for protecting against an infection caused by a bacterium from the species Brachyspira hyodysenteriae. Further, the invention relates to a method for selecting a bacterium from the species Brachyspira hyodysenteriae useful for manufacturing a vaccine against swine dysentery.

Abstract: A Proton Computer Tomography (pCT) system comprising: a position tracker, able to reconstruct the proton trajectory within the body; an energy detector, able to reconstruct the proton energy; wherein, the position tracker is made up of four Depleted Monolithic Active Pixel Sensors (DMAPS) placed in pairs at either side of a phantom, and the energy detector is a Super Thin Range Telescope located downstream comprising a plastic-scintillator made of layers of thin polystyrene bars oriented in alternate axis, perpendicular to the proton beam.

Abstract: An assembly for a vehicle includes a seatbelt buckle, a seatbelt retractor, and webbing retractably extendable from the seatbelt retractor and releasably engageable with the seatbelt buckle. The webbing is extendable from the seatbelt retractor from a fully retracted position toward an extended position. The assembly includes a vibration motor on the seatbelt buckle. The assembly includes a computer having a processor and memory including instructions executable by the processor to activate the vibration motor in response to movement of the webbing from the fully retracted position toward an extended position. The vibration motor provides haptic guidance to an occupant to engage the clip with the seatbelt buckle.

Abstract: Systems and methods for generation and use of vendor management platform architectures are disclosed. A compliance component may be utilized to receive user input data indicating supply contracts between a client and a vendor. The user input data may be utilized to determine insurable obligations associated with the supply contract and provide indications as to whether or not the vendor is compliant with the insurable obligation required by the supply contract. An exposure assessment component may be utilized to determine an exposure score associated with a client account and/or a vendor account based on various compliance factors, spending amounts, and/or properties associated with at least one of goods and/or services that a vendor will supply to a client.

Abstract: Systems and methods for generation and use of vendor management platform architectures are disclosed. A compliance component may be utilized to receive user input data indicating supply contracts between a client and a vendor. The user input data may be utilized to determine insurable obligations associated with the supply contract and provide indications as to whether or not the vendor is compliant with the insurable obligation required by the supply contract. An exposure assessment component may be utilized to determine an exposure score associated with a client account and/or a vendor account based on various compliance factors, spending amounts, and/or properties associated with at least one of goods and/or services that a vendor will supply to a client.

Abstract: The present disclosure provides an all-solid-state electrochemical battery that includes a positive electrode, a negative electrode, and a solid-state electrolyte layer disposed between and separating the positive electrode and the negative electrode. The positive electrode includes a positive electroactive material and a solid-state electrolyte material. The solid-state electrolyte material may be represented by Li3AB6, where A is selected from the group consisting of: yttrium (Y), indium (In), scandium (Sc), erbium (Er), and combinations thereof, and B is selected from the group consisting of: chloride (Cl), bromide (Br), ClxBr(x?1) (where 0<x<1), and combinations thereof. In certain variations, the positive electroactive material includes a nickel-rich electroactive material, and the solid state electrolyte layer includes a sulfide-based electrolyte material. The solid-state electrolyte layer can also include the solid-state electrolyte material may be represented by Li3AB6.

Abstract: In cellular or other wireless networks, relay communication devices can be introduced to support an indirect network connection for remote communication devices in out-of-coverage (OoC) areas to thereby extend access device coverage and increase available data capacity for communication devices that may not be in optimal coverage of an access device. For directly connected communication devices, mechanisms for bit rate recommendation, bit rate query and desired bit rate indication are defined. However, these existing mechanisms do not work for communication devices indirectly connected via a relay communication device. It is therefore proposed to determine a new data rate recommendation and/or limit for one or more downstream communication devices at least partly based on an identity of a logical channel indicated in a received recommendation and/or limit.

Abstract: Described herein are methods and compositions for nerve delivery molecules that carry imaging cargo or therapeutic cargo to the neurons or nerves.

Abstract: The present invention relates to a system that limits resources (e.g. reduces energy consumption and/or peak-to average power ratio) of a wireless communication device by limiting communication resources for the communication device from a network function of the cellular core network.

Abstract: The present invention relates to a system (100) for operating a user device (110) with personalized identity module profiles in which identity module profiles are automatically downloaded from a subscription manager (130) onto a user device (110) upon identification of the user (120) of the user device (110), in a secure manner. The system (100) especially comprises a service system (140) for identifying the user corresponding to the derived user identity, and a subscription manager (130) for preparing personalized identity module profiles requested by the service system (140) and sending the prepared personalized identity module profiles to the user device (110).

Abstract: This document relates to methods and materials for assessing and/or treating mammals (e.g., humans) having endometrial cancer. For example, methods and materials for identifying endometrial cancers likely to respond to a particular cancer treatment (e.g., a platinum based cancer therapy) are provided. This document also relates to materials and methods for using one or more cancer treatments to treat a mammal (e.g., a human) identified as likely to respond to a particular cancer treatment.

Abstract: The invention relates to a method for producing a non-oxide ceramic powder comprising a nitride, a carbide, a boride or at least one MAX phase with the general composition Mn+1AXn, where M=at least one element from the group of transition elements (Sc, Ti, V, Cr, Zr, Nb, Mo, Hf and Ta), A=at least one A group element from the group (Si, Al, Ga, Ge, As, Cd, In, Sn, Tl and Pb), X=carbon (C) and/or nitrogen (N) and/or boron (B), and n=1, 2 or 3. According to the invention, corresponding quantities of elementary starting materials or other precursors are mixed with at least one metal halide salt (NZ), compressed (pellet), and heated for synthesis with a metal halide salt (NZ). The compressed pellet is first enveloped with another metal halide salt, compressed again, arranged in a salt bath and heated therewith until the melting temperature of the salt is exceeded. Optionally, melted silicate can be added, which prevents the salt from evaporating at high temperatures.

Abstract: Disclosed herein is a selective delivery molecule comprising: (a) an acidic sequence (portion A) which is effective to inhibit or prevent the uptake into cells or tissue retention, (b) a molecular transport or tissue retention sequence (portion B), and (c) a linker between portion A and portion B, and (d) cargo moieties (portion DA and DB).

Abstract: A locking mechanism for the folding chassis of electric cutting machines. The chassis (1) comprises: a supporting base (11), a tilting arm (12), and an end arm (13) bearing wheels (14) that are collapsible with respect to a principal arm (10) between a folded and an unfolded position of the chassis. The locking mechanism (2) is installed on the tilting arm (12) and comprises: a locking clip (21) capable of being turned manually between an operative position for the locking of the chassis (1) wherein it is coupled with a number of locking rods (112, 113), and an unlocked position of the chassis (1); a manually displaceable trigger for the retaining of the locking clip in the operational position or the free position; and an elastic element that tends to displace the locking clip (21) and the trigger (22) towards the unlocked position of the chassis (1).

Abstract: Systems and methods for optimizing processing of loan applications are disclosed. A system may include one or more memory devices storing instructions and one or more processors configured to execute the instructions. The instructions may instruct the system to analyze training data to build a predictive model. The instructions may also instruct the system to apply the predictive model to a loan application to determine a first probability of an institution funding the loan application if the institution proactively engages a loan-arranging entity of the loan application and a second probability of the institution funding the loan application if the institution reactively engages the loan-arranging entity. The instructions may further instruct the system to reporting the first and second probabilities to a user through a user interface.

Abstract: The propulsion system for vessels comprises at least one suction sail (3), comprising the suction sail (3) a suction system (10) and a driving unit (8) for driving the rotation of said at least one suction sail (3), in which at least one suction sail (3) also comprises a plurality of sensors (12, 13, 14, 15) connected to a control unit (9), whose control unit determines the operation of the suction system (10) and the transmission unit (8). It permits to provide a propulsion system for vessels that permits to optimize their performance using suction sails.

Abstract: System that enables urine testing in a home environment. A user may apply a urine sample to a card containing multiple tests, and capture an image of the card using a phone; an analysis system executing on the phone or in the cloud may analyze the image and determine test results. The test card and analysis system may compensate for variability in lighting conditions and time of exposure to the urine sample, which are difficult to control in a home environment. The test card may contain fiducial markers of known colors; the analysis system may adjust colors in the captured image based on appearance of these markers. Color adjustments may also compensate for nonuniform lighting across the card. The card may also contain time indicators that change appearance over time after urine is applied, and the analysis system may use these indicators to calculate the time of exposure.