Patents by Inventor Jetze Botma

Jetze Botma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11186861
    Abstract: This invention pertains to the general field of microbiology, and more specifically to transfer, inoculation and/or streaking of micro-organisms, e.g. for the purpose of obtaining individual colonies. Provided is a method for streaking a microbial sample onto a solid carrier, comprising the steps of: a) contacting at least one ferromagnetic particle with a solid carrier, followed or preceded by providing the particle with at least part of said sample, and b) applying a magnetic field gradient to allow for magnetically controlled motion of said particle on said surface, such that at least part of the sample is streaked onto the solid carrier. Also provided is an apparatus for carrying out such method in an (semi-)automated fashion.
    Type: Grant
    Filed: August 1, 2018
    Date of Patent: November 30, 2021
    Assignee: BD KIESTRA B.V.
    Inventors: Trienko Marten Van Der Kaap, Martijn Kleefstra, Ingela Marie Sofie Edlund Tjernberg, Jetze Botma
  • Publication number: 20210055318
    Abstract: A method and apparatus for locating and selecting a colony of microorganisms on a culture dish and identifying microorganisms in said selected colony using MALDI. The method comprises the automated steps of locating and selecting a colony of microorganisms on a culture dish; obtaining a sample of said selected colony of microorganisms; depositing at least some of said sample of said selected colony of microorganisms on a target plate; and transferring said target plate with said sample in an apparatus for performing MALDI for identification of said sample of said selected colony of microorganisms. A sample of a colony of microorganisms is automatically deposited on a depositing spot such that the sample covers at most approximately half of said one of the depositing spots of the target plate.
    Type: Application
    Filed: November 10, 2020
    Publication date: February 25, 2021
    Applicant: BD KIESTRA B.V.
    Inventors: Jetze Botma, Martijn Kleefstra, Tino Walter Van der Zee
  • Patent number: 10859588
    Abstract: A method and apparatus for locating and selecting a colony of microorganisms on a culture dish and identifying microorganisms in said selected colony using MALDI. The method comprises the automated steps of locating and selecting a colony of microorganisms on a culture dish; obtaining a sample of said selected colony of microorganisms; depositing at least some of said sample of said selected colony of microorganisms on a target plate; and transferring said target plate with said sample in an apparatus for performing MALDI for identification of said sample of said selected colony of microorganisms. A sample of a colony of microorganisms is automatically deposited on a depositing spot such that the sample covers at most approximately half of said one of the depositing spots of the target plate.
    Type: Grant
    Filed: October 30, 2019
    Date of Patent: December 8, 2020
    Assignee: BD KIESTRA B.V.
    Inventors: Jetze Botma, Martijn Kleefstra, Tino Walter Van der Zee
  • Publication number: 20200064361
    Abstract: A method and apparatus for locating and selecting a colony of microorganisms on a culture dish and identifying microorganisms in said selected colony using MALDI. The method comprises the automated steps of locating and selecting a colony of microorganisms on a culture dish; obtaining a sample of said selected colony of microorganisms; depositing at least some of said sample of said selected colony of microorganisms on a target plate; and transferring said target plate with said sample in an apparatus for performing MALDI for identification of said sample of said selected colony of microorganisms. A sample of a colony of microorganisms is automatically deposited on a depositing spot such that the sample covers at most approximately half of said one of the depositing spots of the target plate.
    Type: Application
    Filed: October 30, 2019
    Publication date: February 27, 2020
    Applicant: BD KIESTRA B.V.
    Inventors: Jetze Botma, Martijn Kleefstra, Tino Walter Van der Zee
  • Patent number: 10495655
    Abstract: A method and apparatus for locating and selecting a colony of microorganisms on a culture dish and identifying microorganisms in said selected colony using MALDI. The method comprises the automated steps of locating and selecting a colony of microorganisms on a culture dish; obtaining a sample of said selected colony of microorganisms; depositing at least some of said sample of said selected colony of microorganisms on a target plate; and transferring said target plate with said sample in an apparatus for performing MALDI for identification of said sample of said selected colony of microorganisms. A sample of a colony of microorganisms is automatically deposited on a depositing spot such that the sample covers at most approximately half of said one of the depositing spots of the target plate.
    Type: Grant
    Filed: August 8, 2018
    Date of Patent: December 3, 2019
    Assignee: BD KIESTRA B.V.
    Inventors: Jetze Botma, Martijn Kleefstra, Tino Walter Van der Zee
  • Publication number: 20180364264
    Abstract: A method and apparatus for locating and selecting a colony of microorganisms on a culture dish and identifying microorganisms in said selected colony using MALDI. The method comprises the automated steps of locating and selecting a colony of microorganisms on a culture dish; obtaining a sample of said selected colony of microorganisms; depositing at least some of said sample of said selected colony of microorganisms on a target plate; and transferring said target plate with said sample in an apparatus for performing MALDI for identification of said sample of said selected colony of microorganisms. A sample of a colony of microorganisms is automatically deposited on a depositing spot such that the sample covers at most approximately half of said one of the depositing spots of the target plate.
    Type: Application
    Filed: August 8, 2018
    Publication date: December 20, 2018
    Applicant: BD KIESTRA B.V.
    Inventors: Jetze Botma, Martijn Kleefstra, Tino Walter Van der Zee
  • Publication number: 20180340205
    Abstract: This invention pertains to the general field of microbiology, and more specifically to transfer, inoculation and/or streaking of micro-organisms, e.g. for the purpose of obtaining individual colonies. Provided is a method for streaking a microbial sample onto a solid carrier, comprising the steps of: a) contacting at least one ferromagnetic particle with a solid carrier, followed or preceded by providing the particle with at least part of said sample, and b) applying a magnetic field gradient to allow for magnetically controlled motion of said particle on said surface, such that at least part of the sample is streaked onto the solid carrier. Also provided is an apparatus for carrying out such method in an (semi-)automated fashion.
    Type: Application
    Filed: August 1, 2018
    Publication date: November 29, 2018
    Applicant: BD KIESTRA B.V.
    Inventors: Trienko Marten Van Der Kaap, Martijn Kleefstra, lngela Marie Sofie Edlund Tjernberg, Jetze Botma
  • Patent number: 10073105
    Abstract: A method and apparatus for locating and selecting a colony of microorganisms on a culture dish and identifying microorganisms in said selected colony using MALDI. The method comprises the automated steps of locating and selecting a colony of microorganisms on a culture dish; obtaining a sample of said selected colony of microorganisms; depositing at least some of said sample of said selected colony of microorganisms on a target plate; and transferring said target plate with said sample in an apparatus for performing MALDI for identification of said sample of said selected colony of microorganisms. A sample of a colony of microorganisms is automatically deposited on a depositing spot such that the sample covers at most approximately half of said one of the depositing spots of the target plate.
    Type: Grant
    Filed: July 28, 2017
    Date of Patent: September 11, 2018
    Assignee: BD Kiestra B.V.
    Inventors: Jetze Botma, Martijn Kleefstra, Tino Walter Van der Zee
  • Patent number: 10072281
    Abstract: This invention pertains to the general field of microbiology, and more specifically to transfer, inoculation and/or streaking of micro-organisms, e.g. for the purpose of obtaining individual colonies. Provided is a method for transferring a microbial sample from a first carrier to a second carrier, comprising the steps of: a) contacting at least one ferromagnetic particle with at least part of the sample associated with the first carrier, wherein the particle is a composite bead having a surface roughness (Ra) in the range of 0.1 to 25 ?m, a diameter between 2 to 88 mm and a density below 7 g/cm3, and b) applying a magnetic field gradient to allow for magnetically controlled motion of said particle to said second carrier, such that at least part of the sample is streaked onto the second carrier. Also provided is an apparatus for inoculating petri dishes with the sample according to the method and also inoculating slides and/or tubes with a portion of the sample.
    Type: Grant
    Filed: August 18, 2015
    Date of Patent: September 11, 2018
    Assignee: BD Kiestra B.V.
    Inventors: Trienko Marten Van Der Kaap, Martijn Kleefstra, Ingela Marie Sofie Edlund Tjernberg, Jetze Botma
  • Publication number: 20170336426
    Abstract: A method and apparatus for locating and selecting a colony of microorganisms on a culture dish and identifying microorganisms in said selected colony using MALDI. The method comprises the automated steps of locating and selecting a colony of microorganisms on a culture dish; obtaining a sample of said selected colony of microorganisms; depositing at least some of said sample of said selected colony of microorganisms on a target plate; and transferring said target plate with said sample in an apparatus for performing MALDI for identification of said sample of said selected colony of microorganisms. A sample of a colony of microorganisms is automatically deposited on a depositing spot such that the sample covers at most approximately half of said one of the depositing spots of the target plate.
    Type: Application
    Filed: July 28, 2017
    Publication date: November 23, 2017
    Applicant: BD KIESTRA B.V
    Inventors: Jetze Botma, Martijn Kleefstra, Tino Walter Van der Zee
  • Patent number: 9753045
    Abstract: A method and apparatus for locating and selecting a colony of microorganisms on a culture dish and identifying microorganisms in said selected colony using MALDI. The method comprises the automated steps of locating and selecting a colony of microorganisms on a culture dish; obtaining a sample of said selected colony of microorganisms; depositing at least some of said sample of said selected colony of microorganisms on a target plate; and transferring said target plate with said sample in an apparatus for performing MALDI for identification of said sample of said selected colony of microorganisms. A sample of a colony of microorganisms is automatically deposited on a depositing spot such that the sample covers at most approximately half of said one of the depositing spots of the target plate.
    Type: Grant
    Filed: December 19, 2016
    Date of Patent: September 5, 2017
    Assignee: BD KIESTRA B.V.
    Inventors: Jetze Botma, Martijn Kleefstra, Tino Walter Van Der Zee
  • Patent number: 9677044
    Abstract: In a method for picking up cell material from a culture dish a picking tool is displaced towards the cell material. Contact between the tool and the cell material is determined by carrying out capacitive measurements. After contact the tool is removed from the cell material. In an assembly for performing said method a support made of electrically conducting material supports the dish. A measurement device determines the start electrical capacity of the system composed of picking tool and support in a starting position of the tool, and determines the electrical capacity of the system when lowering the tool towards the dish. The measurement device provides signals representing the electrical capacity to a controller, which comprises a comparator for performing a comparison of the electrical capacity during lowering of the tool with the start electrical capacity. The controller controls the positioning of the tool at least based on this comparison.
    Type: Grant
    Filed: September 28, 2012
    Date of Patent: June 13, 2017
    Assignee: BD Keistra B.V.
    Inventors: Jetze Botma, Martijn Kleefstra, Martijn Xander Berntsen, Tino Walter Van Der Zee
  • Publication number: 20170097368
    Abstract: A method and apparatus for locating and selecting a colony of microorganisms on a culture dish and identifying microorganisms in said selected colony using MALDI. The method comprises the automated steps of locating and selecting a colony of microorganisms on a culture dish; obtaining a sample of said selected colony of microorganisms; depositing at least some of said sample of said selected colony of microorganisms on a target plate; and transferring said target plate with said sample in an apparatus for performing MALDI for identification of said sample of said selected colony of microorganisms. A sample of a colony of microorganisms is automatically deposited on a depositing spot such that the sample covers at most approximately half of said one of the depositing spots of the target plate.
    Type: Application
    Filed: December 19, 2016
    Publication date: April 6, 2017
    Applicant: BD Kiestra B.V.
    Inventors: Jetze Botma, Martijn Kleefstra, Tino Walter Van Der Zee
  • Patent number: 9556495
    Abstract: A method and apparatus for locating and selecting a colony of microorganisms on a culture dish and identifying microorganisms in said selected colony using MALDI. The method comprises the automated steps of locating and selecting a colony of microorganisms on a culture dish; obtaining a sample of said selected colony of microorganisms; depositing at least some of said sample of said selected colony of microorganisms on a target plate; and transferring said target plate with said sample in an apparatus for performing MALDI for identification of said sample of said selected colony of microorganisms. A sample of a colony of microorganisms is automatically deposited on a depositing spot such that the sample covers at most approximately half of said one of the depositing spots of the target plate.
    Type: Grant
    Filed: April 2, 2013
    Date of Patent: January 31, 2017
    Assignee: BD Kiestra B.V.
    Inventors: Jetze Botma, Martijn Kleefstra, Tino Walter Van Der Zee
  • Patent number: 9557343
    Abstract: Disc dispensing device for dispensing discs impregnated with antibiotics onto a culture dish. The device comprises a stationary support on which a magazine is removably mounted. The magazine holds a plurality of tubular containers each containing a stack of discs to be dispensed. A moving means moves one disc from a bottom end of a tubular container to a pick-up position. From the pick-up position a transfer means picks up said one disc and transfers it to the culture dish where it is dispensed. The removable culture dish is supported by a moveable carriage which is mounted on the stationary support. The carriage is moveable relative to the magazine from a starting position to an operating position and vice versa. Control means control the operation of the device. The plurality of tubular containers is rotatable around a magazine centre under control of the control means.
    Type: Grant
    Filed: March 27, 2015
    Date of Patent: January 31, 2017
    Assignee: BD Kiestra B.V.
    Inventors: Jetze Botma, Martijn Kleefstra, Trienko Marten Van Der Kaap, Martijn Xander Berntsen, Jan Bart Van Der Vijver
  • Publication number: 20160032351
    Abstract: This invention pertains to the general field of microbiology, and more specifically to transfer, inoculation and/or streaking of micro-organisms, e.g. for the purpose of obtaining individual colonies. Provided is a method for transferring a microbial sample from a first carrier to a second carrier, comprising the steps of: a) contacting at least one ferromagnetic particle with at least part of the sample associated with the first carrier, wherein the particle is a composite bead having a surface roughness (Ra) in the range of 0.1 to 25 ?m, a diameter between 2 to 88 mm and a density below 7 g/cm3, and b) applying a magnetic field gradient to allow for magnetically controlled motion of said particle to said second carrier, such that at least part of the sample is streaked onto the second carrier. Also provided is an apparatus for inoculating petri dishes with the sample according to the method and also inoculating slides and/or tubes with a portion of the sample.
    Type: Application
    Filed: August 18, 2015
    Publication date: February 4, 2016
    Inventors: Trienko Marten Van Der Kaap, Martijn Kleefstra, Ingela Marie Sofie Edlund Tjernberg, Jetze Botma
  • Patent number: 9121005
    Abstract: This invention pertains to the general field of microbiology, and more specifically to transfer, inoculation and/or streaking of micro-organisms, e.g. for the purpose of obtaining individual colonies. Provided is a method for streaking a microbial sample onto a solid carrier, comprising the steps of: a) contacting at least one ferromagnetic particle with a solid carrier, followed or preceded by providing the particle with at least part of said sample, and b) applying a magnetic field gradient to allow for magnetically controlled motion of said particle on said surface, such that at least part of the sample is streaked onto the solid carrier. Also provided is an apparatus for carrying out such method in an (semi-)automated fashion.
    Type: Grant
    Filed: November 4, 2008
    Date of Patent: September 1, 2015
    Assignee: BD Kiestra B.V.
    Inventors: Trienko Marten van der Kaap, Martijn Kleefstra, Ingeta Marie Sofie Edlund Tjernberg, Jetze Botma
  • Publication number: 20150198622
    Abstract: Disc dispensing device for dispensing discs impregnated with antibiotics onto a culture dish. The device comprises a stationary support on which a magazine is removably mounted. The magazine holds a plurality of tubular containers each containing a stack of discs to be dispensed. A moving means moves one disc from a bottom end of a tubular container to a pick-up position. From the pick-up position a transfer means picks up said one disc and transfers it to the culture dish where it is dispensed. The removable culture dish is supported by a moveable carriage which is mounted on the stationary support. The carriage is moveable relative to the magazine from a starting position to an operating position and vice versa. Control means control the operation of the device. The plurality of tubular containers is rotatable around a magazine centre under control of the control means.
    Type: Application
    Filed: March 27, 2015
    Publication date: July 16, 2015
    Applicant: BD Kiestra B.V.
    Inventors: Jetze Botma, Martijn Kleefstra, Trienko Marten Van Der Kaap, Martijn Xander Berntsen, Jan Bart Van Der Vijver
  • Patent number: 8996163
    Abstract: Disc dispensing device for dispensing discs impregnated with antibiotics onto a culture dish. The device comprises a stationary support on which a magazine is removably mounted. The magazine holds a plurality of tubular containers each containing a stack of discs to be dispensed. A moving means moves one disc from a bottom end of a tubular container to a pick-up position. From the pick-up position a transfer means picks up said one disc and transfers it to the culture dish where it is dispensed. The removable culture dish is supported by a moveable carriage which is mounted on the stationary support. The carriage is moveable relative to the magazine from a starting position to an operating position and vice versa. Control means control the operation of the device. The plurality of tubular containers is rotatable around a magazine center under control of the control means.
    Type: Grant
    Filed: April 27, 2012
    Date of Patent: March 31, 2015
    Assignee: BD Kiestra B.V.
    Inventors: Jetze Botma, Martijn Kleefstra, Trienko Marten van der Kaap, Martijn Xander Berntsen, Jan Bart van der Vijver
  • Publication number: 20150086971
    Abstract: A method and apparatus for locating and selecting a colony of microorganisms on a culture dish and identifying microorganisms in said selected colony using MALDI. The method comprises the automated steps of locating and selecting a colony of microorganisms on a culture dish; obtaining a sample of said selected colony of microorganisms; depositing at least some of said sample of said selected colony of microorganisms on a target plate; and transferring said target plate with said sample in an apparatus for performing MALDI for identification of said sample of said selected colony of microorganisms. A sample of a colony of microorganisms is automatically deposited on a depositing spot such that the sample covers at most approximately half of said one of the depositing spots of the target plate.
    Type: Application
    Filed: April 2, 2013
    Publication date: March 26, 2015
    Applicant: BD Kiestra B.V.
    Inventors: Jetze Botma, Martijn Kleefstra, Tino Walter Van Der Zee