Patents by Inventor JHENG-GANG YANG

JHENG-GANG YANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibody-containing aqueous formulation and use thereof
    Patent number: 11427639
    Abstract: The present disclosure provides an antibody-containing aqueous formulation, comprising a therapeutically effective amount of an anti-interleukin-6 receptor antibody, a protein stabilizer, a surfactant, and a buffer. The buffer is an acetate buffer or a histidine buffer, and the antibody-containing aqueous formulation has a pH ranging from 4.5 to 6.5.
    Type: Grant
    Filed: April 1, 2019
    Date of Patent: August 30, 2022
    Inventors: Jheng-Gang Yang, Jiung-Liang Liu, Wen-Cheng Chang
  • AQUEOUS PHARMACEUTICAL FORMULATIONS
    Publication number: 20210393783
    Abstract: Provided are an aqueous pharmaceutical formulation comprising an antibody specific to the receptor of interleukin (IL)-6 (for example, Tocilizumab) and an effective amount of histidine for stabilizing the antibody. Said histidine is present in the aqueous pharmaceutical formulation at a concentration of 50 mM to 200 mM so as to achieve the stabilizing effect.
    Type: Application
    Filed: October 24, 2019
    Publication date: December 23, 2021
    Inventors: Jheng-Gang Yang, Wen-Cheng Chang, Jiung-Liang Liu
  • ANTIBODY-CONTAINING AQUEOUS FORMULATION AND USE THEREOF
    Publication number: 20190300615
    Abstract: The present disclosure provides an antibody-containing aqueous formulation, comprising a therapeutically effective amount of an anti-interleukin-6 receptor antibody, a protein stabilizer, a surfactant, and a buffer. The buffer is an acetate buffer or a histidine buffer, and the antibody-containing aqueous formulation has a pH ranging from 4.5 to 6.5.
    Type: Application
    Filed: April 1, 2019
    Publication date: October 3, 2019
    Inventors: JHENG-GANG YANG, JIUNG-LIANG LIU, WEN-CHENG CHANG