Patents by Inventor Jheng-Sian LI

Jheng-Sian LI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LIPID COMPOUND OR A DERIVATIVE THEREOF AND PHARMACEUTICAL COMPOSITION EMPLOYING THE SAME
    Publication number: 20240189243
    Abstract: A lipid compound or a derivative thereof and a pharmaceutical composition employing the same are provided. The lipid compound has a structure represented by Formula (I): wherein Z1, Z2, Z3 and Z4 are as disclosed in the specification.
    Type: Application
    Filed: November 13, 2023
    Publication date: June 13, 2024
    Applicant: Industrial Technology Research Institute
    Inventors: Felice Cheng, Ping-Fu Cheng, Jenn-Tsang Hwang, Chih-Wei Fu, Ku-Feng Lin, Ya-Ling Chiu, Jheng-Sian Li, Kang-Li Wang, Siou-Han Chang, Chia-Yu Fan
  • IMMUNOSTIMULATORY LIPOPLEX, PHARMACEUTICAL COMPOSITION INCLUDING IMMUNOSTIMULATORY LIPOPLEX, AND USES THEREOF
    Publication number: 20220202952
    Abstract: An immunostimulatory lipoplex is provided. The immunostimulatory lipoplex includes a liposome and at least one immunostimulatory nucleic acid drug, and the immunostimulatory nucleic acid drug is complexed with the liposome The liposome includes 40 to 85 mol % of cationic lipid, 10 to 50 mol % of cholesterol, and 0.001 to 20 mol % of modified polyethylene glycol lipid.
    Type: Application
    Filed: December 23, 2021
    Publication date: June 30, 2022
    Applicant: Industrial Technology Research Institute
    Inventors: Neng-Chang YU, Felice CHENG, Chih-Peng LIU, Ming-Hsi WU, Shih-Ta CHEN, Chia-Mu TU, Li-Wen CHANG, Jheng-Sian LI, Meng-Ping SHE, Hsiang-Ching WANG
  • Antibody-drug conjugate (ADC) and method for forming the same
    Patent number: 10618935
    Abstract: An antibody-drug conjugate (ADC) of formula (I) or a pharmaceutically acceptable salt or solvate thereof is provided. In formula (I), p is an integer ranging from 1 to 26, A is an antibody, and -(L-D) is a linker-drug unit. L is a linker unit having a glycopeptide, and D is a drug unit. The antibody is conjugated to the linker unit through a cysteine residue of the antibody. A method for forming an antibody-drug conjugate (ADC) is also provided.
    Type: Grant
    Filed: November 2, 2016
    Date of Patent: April 14, 2020
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Yi-Ju Ko, Jheng-Sian Li, Maggie Lu, On Lee, Ping-Fu Cheng, Chun-Min Liu
  • ANTIBODY-DRUG CONJUGATE (ADC) AND METHOD FOR FORMING THE SAME
    Publication number: 20170119902
    Abstract: An antibody-drug conjugate (ADC) of formula (I) or a pharmaceutically acceptable salt or solvate thereof is provided. In formula (I), p is an integer ranging from 1 to 26, A is an antibody, and -(L-D) is a linker-drug unit. L is a linker unit having a glycopeptide, and D is a drug unit. The antibody is conjugated to the linker unit through a cysteine residue of the antibody. A method for forming an antibody-drug conjugate (ADC) is also provided.
    Type: Application
    Filed: November 2, 2016
    Publication date: May 4, 2017
    Applicant: Industrial Technology Research Institute
    Inventors: Yi-Ju KO, Jheng-Sian LI, Maggie LU, On LEE, Ping-Fu CHENG, Chun-Min LIU